Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1996222Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 1996223Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 1996224Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 1996231Protein MDM2 [47594] (2 species)
  7. 1996249Species Human (Homo sapiens) [TaxId:9606] [47596] (58 PDB entries)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1rv1:
    1. 1996318Domain d1rv1a_: 1rv1 A: [97901]
      complexed with imz
    2. 1996319Domain d1rv1b_: 1rv1 B: [97902]
      complexed with imz
    3. 1996320Domain d1rv1c_: 1rv1 C: [97903]
      complexed with imz
  2. Domain(s) for 1t4e:
    1. 1996328Domain d1t4ea2: 1t4e A:17-111 [119142]
      Other proteins in same PDB: d1t4ea3, d1t4eb3
      automated match to d1rv1a_
      complexed with diz
    2. 1996329Domain d1t4eb2: 1t4e B:17-111 [119143]
      Other proteins in same PDB: d1t4ea3, d1t4eb3
      automated match to d1rv1a_
      complexed with diz
  3. Domain(s) for 1t4f:
  4. Domain(s) for 1ycr:
  5. Domain(s) for 2axi:
  6. Domain(s) for 2gv2:
  7. Domain(s) for 2lzg:
  8. Domain(s) for 2mps:
  9. Domain(s) for 3g03:
    1. 1996264Domain d3g03a_: 3g03 A: [176230]
      automated match to d1rv1a_
    2. 1996265Domain d3g03c_: 3g03 C: [176231]
      automated match to d1rv1a_
  10. Domain(s) for 3jzk:
  11. Domain(s) for 3jzr:
  12. Domain(s) for 3jzs:
  13. Domain(s) for 3lbk:
  14. Domain(s) for 3lbl:
    1. 1996254Domain d3lbla1: 3lbl A:18-110 [180164]
      Other proteins in same PDB: d3lbla2
      automated match to d1rv1a_
      complexed with mi6
    2. 1996255Domain d3lblc_: 3lbl C: [180165]
      Other proteins in same PDB: d3lbla2
      automated match to d1rv1a_
      complexed with mi6
    3. 1996256Domain d3lble_: 3lbl E: [180166]
      Other proteins in same PDB: d3lbla2
      automated match to d1rv1a_
      complexed with mi6
  15. Domain(s) for 3tj2:
    1. 1996306Domain d3tj2a_: 3tj2 A: [192477]
      automated match to d1t4ea_
      protein/DNA complex; complexed with k, tj2
    2. 1996307Domain d3tj2c_: 3tj2 C: [192476]
      automated match to d1t4ea_
      protein/DNA complex; complexed with k, tj2
  16. Domain(s) for 3tu1:
  17. Domain(s) for 3v3b:
    1. 1996301Domain d3v3ba_: 3v3b A: [186458]
      automated match to d1rv1a_
      protein/DNA complex; complexed with cl
    2. 1996302Domain d3v3bb_: 3v3b B: [186459]
      automated match to d1rv1a_
      protein/DNA complex; complexed with cl
  18. Domain(s) for 3vbg:
    1. 1996335Domain d3vbga_: 3vbg A: [195030]
      automated match to d1rv1a_
      complexed with 03m
    2. 1996336Domain d3vbgb_: 3vbg B: [201219]
      automated match to d1rv1a_
      complexed with 03m
    3. 1996337Domain d3vbgc_: 3vbg C: [195029]
      automated match to d1rv1a_
      complexed with 03m
    4. 1996338Domain d3vbgd_: 3vbg D: [195031]
      automated match to d1rv1a_
      complexed with 03m
  19. Domain(s) for 3vzv:
    1. 1996339Domain d3vzva_: 3vzv A: [201266]
      automated match to d3vzvb_
      complexed with vzv
    2. 1996340Domain d3vzvb_: 3vzv B: [193259]
      automated match to d1rv1a_
      complexed with vzv
  20. Domain(s) for 3w69:
    1. 1996304Domain d3w69a_: 3w69 A: [197281]
      automated match to d1rv1a_
      complexed with ltz, so4
    2. 1996305Domain d3w69b_: 3w69 B: [201283]
      automated match to d3vzvb_
      complexed with ltz, so4
  21. Domain(s) for 4dij:
    1. 1996261Domain d4dija_: 4dij A: [195473]
      automated match to d3jzra_
      complexed with blf
    2. 1996262Domain d4dijb_: 4dij B: [195472]
      automated match to d3jzra_
      complexed with blf
  22. Domain(s) for 4ere:
    1. 1996280Domain d4erea_: 4ere A: [192401]
      automated match to d1t4ea_
      complexed with 0r2, so4
    2. 1996281Domain d4ereb_: 4ere B: [192402]
      automated match to d1t4ea_
      complexed with 0r2, so4
  23. Domain(s) for 4erf:
    1. 1996292Domain d4erfa_: 4erf A: [192403]
      automated match to d1t4ea_
      complexed with 0r3
    2. 1996293Domain d4erfc_: 4erf C: [192404]
      automated match to d1t4ea_
      complexed with 0r3
    3. 1996294Domain d4erfe_: 4erf E: [192405]
      automated match to d1t4ea_
      complexed with 0r3
  24. Domain(s) for 4hbm:
    1. 1996272Domain d4hbma_: 4hbm A: [202405]
      automated match to d4hbme_
      complexed with 0y7
    2. 1996273Domain d4hbmb_: 4hbm B: [202406]
      automated match to d4hbme_
      complexed with 0y7
    3. 1996274Domain d4hbmc_: 4hbm C: [202407]
      automated match to d4hbme_
      complexed with 0y7
    4. 1996275Domain d4hbmd_: 4hbm D: [202408]
      automated match to d4hbme_
      complexed with 0y7
    5. 1996276Domain d4hbme_: 4hbm E: [193444]
      automated match to d3jzra_
      complexed with 0y7
    6. 1996277Domain d4hbmf_: 4hbm F: [202409]
      automated match to d4hbme_
      complexed with 0y7
    7. 1996278Domain d4hbmg_: 4hbm G: [202410]
      automated match to d4hbme_
      complexed with 0y7
    8. 1996279Domain d4hbmh_: 4hbm H: [202411]
      automated match to d4hbme_
      complexed with 0y7
  25. Domain(s) for 4hg7:
  26. Domain(s) for 4jv7:
  27. Domain(s) for 4jv9:
  28. Domain(s) for 4jve:
  29. Domain(s) for 4jvr:
    1. 1996266Domain d4jvra_: 4jvr A: [196976]
      automated match to d4ereb_
      complexed with 1mt
    2. 1996267Domain d4jvrc_: 4jvr C: [202809]
      automated match to d4jvra_
      complexed with 1mt
    3. 1996268Domain d4jvre_: 4jvr E: [202810]
      automated match to d4jvra_
      complexed with 1mt
  30. Domain(s) for 4jwr:
    1. 1996315Domain d4jwra_: 4jwr A: [197258]
      automated match to d4ereb_
      complexed with 1my
    2. 1996316Domain d4jwrb_: 4jwr B: [196977]
      automated match to d4ereb_
      complexed with 1my
    3. 1996317Domain d4jwrc_: 4jwr C: [202812]
      automated match to d4jwrb_
      complexed with 1my
  31. Domain(s) for 4mdn:
  32. Domain(s) for 4mdq:
  33. Domain(s) for 4oas:
    1. 1996269Domain d4oasa_: 4oas A: [237088]
      automated match to d1t4ea_
      complexed with 2sw, so4
    2. 1996270Domain d4oasc_: 4oas C: [237089]
      automated match to d1t4ea_
      complexed with 2sw, so4
    3. 1996271Domain d4oase_: 4oas E: [237087]
      automated match to d1t4ea_
      complexed with 2sw, so4
  34. Domain(s) for 4oba:
    1. 1996289Domain d4obaa_: 4oba A: [237866]
      automated match to d1t4ea_
      complexed with 2tw
    2. 1996290Domain d4obab_: 4oba B: [237867]
      automated match to d1t4ea_
      complexed with 2tw
    3. 1996291Domain d4obac_: 4oba C: [237868]
      automated match to d1t4ea_
      complexed with 2tw
  35. Domain(s) for 4occ:
    1. 1996285Domain d4occa_: 4occ A: [238273]
      automated match to d1t4ea_
      complexed with 2tz
    2. 1996286Domain d4occc_: 4occ C: [238272]
      automated match to d1t4ea_
      complexed with 2tz
    3. 1996287Domain d4occe_: 4occ E: [238274]
      automated match to d1t4ea_
      complexed with 2tz
  36. Domain(s) for 4ode:
  37. Domain(s) for 4odf:
  38. Domain(s) for 4ogn:
  39. Domain(s) for 4ogt:
  40. Domain(s) for 4ogv:
    1. 1996331Domain d4ogva_: 4ogv A: [238277]
      automated match to d4jwra_
      complexed with 2u7
    2. 1996332Domain d4ogvb_: 4ogv B: [238278]
      automated match to d4jwra_
      complexed with 2u7
    3. 1996333Domain d4ogvc_: 4ogv C: [238279]
      automated match to d4jwra_
      complexed with 2u7
  41. Domain(s) for 4oq3:
    1. 1996322Domain d4oq3a_: 4oq3 A: [257309]
      automated match to d3jzra_
      complexed with 2v8
    2. 1996323Domain d4oq3b_: 4oq3 B: [263323]
      automated match to d3jzra_
      complexed with 2v8
    3. 1996324Domain d4oq3c_: 4oq3 C: [263324]
      automated match to d3jzra_
      complexed with 2v8
    4. 1996325Domain d4oq3d_: 4oq3 D: [263325]
      automated match to d3jzra_
      complexed with 2v8
  42. Domain(s) for 4qo4:
  43. Domain(s) for 4qoc:
    1. 1996295Domain d4qoca_: 4qoc A: [272374]
      automated match to d1t4ea_
      complexed with 35t
    2. 1996296Domain d4qocc_: 4qoc C: [272373]
      automated match to d1t4ea_
      complexed with 35t
    3. 1996297Domain d4qoce_: 4qoc E: [272376]
      automated match to d1t4ea_
      complexed with 35t
    4. 1996298Domain d4qocg_: 4qoc G: [272371]
      automated match to d1t4ea_
      complexed with 35t
    5. 1996299Domain d4qoci_: 4qoc I: [272372]
      automated match to d1t4ea_
      complexed with 35t
    6. 1996300Domain d4qock_: 4qoc K: [272375]
      automated match to d1t4ea_
      complexed with 35t
  44. Domain(s) for 4wt2:
  45. Domain(s) for 4zfi:
    1. 2280995Domain d4zfib_: 4zfi B: [324296]
      automated match to d5hmia_
      complexed with 4nj
    2. 2281015Domain d4zfic_: 4zfi C: [324316]
      automated match to d5hmia_
      complexed with 4nj
    3. 2281020Domain d4zfid_: 4zfi D: [324321]
      automated match to d5hmia_
      complexed with 4nj
    4. 2281022Domain d4zfia_: 4zfi A: [324323]
      automated match to d5hmia_
      complexed with 4nj
  46. Domain(s) for 4zgk:
    1. 2280975Domain d4zgka1: 4zgk A:18-110 [324276]
      Other proteins in same PDB: d4zgka2
      automated match to d1ttva_
      complexed with 4nx
    2. 2280977Domain d4zgkb_: 4zgk B: [324278]
      Other proteins in same PDB: d4zgka2
      automated match to d1ttva_
      complexed with 4nx
  47. Domain(s) for 4zyc:
    1. 1996311Domain d4zyca_: 4zyc A: [275315]
      automated match to d3jzra_
      complexed with 4ss, so4
    2. 1996312Domain d4zycb_: 4zyc B: [275316]
      automated match to d3jzra_
      complexed with 4ss, so4
    3. 1996313Domain d4zycc_: 4zyc C: [275317]
      automated match to d3jzra_
      complexed with 4ss, so4
  48. Domain(s) for 4zyf:
  49. Domain(s) for 4zyi:
  50. Domain(s) for 5c5a:
    1. 2275621Domain d5c5aa_: 5c5a A: [318922]
      automated match to d4ereb_
      complexed with cl, iod, nut, so4
    2. 2275638Domain d5c5ab_: 5c5a B: [318939]
      automated match to d4ereb_
      complexed with cl, iod, nut, so4
  51. Domain(s) for 5hmh:
    1. 2271444Domain d5hmhb1: 5hmh B:21-116 [314747]
      Other proteins in same PDB: d5hmha2, d5hmhb2
      automated match to d1ttva_
    2. 2271480Domain d5hmha1: 5hmh A:21-113 [314781]
      Other proteins in same PDB: d5hmha2, d5hmhb2
      automated match to d1ttva_
      complexed with 62r, so4
  52. Domain(s) for 5hmi:
    1. 2271490Domain d5hmib1: 5hmi B:20-116 [314791]
      Other proteins in same PDB: d5hmib2
      automated match to d1ttva_
      complexed with 62t, so4
    2. 2271503Domain d5hmia_: 5hmi A: [314804]
      Other proteins in same PDB: d5hmib2
      automated match to d1ttva_
      complexed with 62t, so4
  53. Domain(s) for 5hmk:
    1. 2271484Domain d5hmkb_: 5hmk B: [314785]
      automated match to d1ttva_
      complexed with 62q
    2. 2271504Domain d5hmka_: 5hmk A: [314805]
      automated match to d1ttva_
      complexed with 62q
  54. Domain(s) for 5j7f:
    1. 2290784Domain d5j7fa_: 5j7f A: [334085]
      automated match to d2lzga_
      complexed with 6gg
    2. 2290786Domain d5j7fc_: 5j7f C: [334087]
      automated match to d2lzga_
      complexed with 6gg
    3. 2290788Domain d5j7fd_: 5j7f D: [334090]
      automated match to d2lzga_
      complexed with 6gg
    4. 2290921Domain d5j7fb_: 5j7f B: [334222]
      automated match to d2lzga_
      complexed with 6gg
  55. Domain(s) for 5j7g:
    1. 2290780Domain d5j7gb_: 5j7g B: [334081]
      Other proteins in same PDB: d5j7ga2
      automated match to d1ttva_
      complexed with 6gg
    2. 2290877Domain d5j7ga1: 5j7g A:18-110 [334178]
      Other proteins in same PDB: d5j7ga2
      automated match to d1ttva_
      complexed with 6gg
    3. 2290904Domain d5j7gd_: 5j7g D: [334205]
      Other proteins in same PDB: d5j7ga2
      automated match to d1ttva_
      complexed with 6gg
    4. 2290987Domain d5j7gc_: 5j7g C: [334288]
      Other proteins in same PDB: d5j7ga2
      automated match to d1ttva_
      complexed with 6gg
  56. Domain(s) for 5lav:
  57. Domain(s) for 5lay:
    1. 2281406Domain d5laye_: 5lay E: [324707]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
    2. 2281411Domain d5layf_: 5lay F: [324712]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
    3. 2281426Domain d5layc_: 5lay C: [324727]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
    4. 2281428Domain d5layd_: 5lay D: [324729]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
    5. 2281432Domain d5layb_: 5lay B: [324733]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
    6. 2281435Domain d5laya_: 5lay A: [324736]
      automated match to d4ereb_
      complexed with 6ss, gol, so4
  58. Domain(s) for 5trf:
    1. 2282788Domain d5trfb_: 5trf B: [326089]
      automated match to d2lzga_
      complexed with 7hc, gol, so4
    2. 2282808Domain d5trfd_: 5trf D: [326109]
      automated match to d2lzga_
      complexed with 7hc, gol, so4
    3. 2282822Domain d5trfe_: 5trf E: [326123]
      automated match to d2lzga_
      complexed with 7hc, gol, so4
    4. 2282870Domain d5trfa_: 5trf A: [326171]
      automated match to d2lzga_
      complexed with 7hc, gol, so4
    5. 2282877Domain d5trfc_: 5trf C: [326178]
      automated match to d2lzga_
      complexed with 7hc, gol, so4

More info for Species Human (Homo sapiens) [TaxId:9606] from a.42.1.1 MDM2

Timeline for Species Human (Homo sapiens) [TaxId:9606] from a.42.1.1 MDM2: