Lineage for d4oq3d_ (4oq3 D:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321461Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2321462Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2321463Family a.42.1.1: SWIB/MDM2 domain [47593] (5 proteins)
    Pfam PF02201
  6. 2321470Protein MDM2 [47594] (2 species)
  7. 2321488Species Human (Homo sapiens) [TaxId:9606] [47596] (69 PDB entries)
  8. 2321600Domain d4oq3d_: 4oq3 D: [263325]
    automated match to d3jzra_
    complexed with 2v8

Details for d4oq3d_

PDB Entry: 4oq3 (more details), 2.3 Å

PDB Description: tetra-substituted imidazoles as a new class of inhibitors of the p53- mdm2 interaction
PDB Compounds: (D:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d4oq3d_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4oq3d_ a.42.1.1 (D:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4oq3d_:

Click to download the PDB-style file with coordinates for d4oq3d_.
(The format of our PDB-style files is described here.)

Timeline for d4oq3d_: