Lineage for d5hmib1 (5hmi B:20-116)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321461Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2321462Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2321463Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 2321470Protein MDM2 [47594] (2 species)
  7. 2321488Species Human (Homo sapiens) [TaxId:9606] [47596] (62 PDB entries)
  8. 2321544Domain d5hmib1: 5hmi B:20-116 [314791]
    Other proteins in same PDB: d5hmib2
    automated match to d1ttva_
    complexed with 62t, so4

Details for d5hmib1

PDB Entry: 5hmi (more details), 1.74 Å

PDB Description: hdm2 in complex with a 3,3-disubstituted piperidine
PDB Compounds: (B:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d5hmib1:

Sequence; same for both SEQRES and ATOM records: (download)

>d5hmib1 a.42.1.1 (B:20-116) MDM2 {Human (Homo sapiens) [TaxId: 9606]}
paseqetlvrpkplllkllksvgaqkdtytmkevlyylgqyimtkrlydekqqhivhcsn
dllgdlfgvpsfsvkehrkiytmiyrnlvvvnqqess

SCOPe Domain Coordinates for d5hmib1:

Click to download the PDB-style file with coordinates for d5hmib1.
(The format of our PDB-style files is described here.)

Timeline for d5hmib1:

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Domains from same chain:
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d5hmib2
View in 3D
Domains from other chains:
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d5hmia_