PDB entry 6q9h

View 6q9h on RCSB PDB site
Description: HDM2 (17-111, WILD TYPE) COMPLEXED WITH COMPOUND 11 AT 2.0A; Structural states of Hdm2 and HdmX: X-ray elucidation of adaptations and binding interactions for different chemical compound classes
Class: ligase
Keywords: PPI with p53, inhibitor complex, cell cycle, LIGASE
Deposited on 2018-12-18, released 2019-05-15
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-07-24, with a file datestamp of 2019-07-19.
Experiment type: XRAY
Resolution: 2 Å
R-factor: N/A
AEROSPACI score: 0.31 (click here for full SPACI score report)

Chains and heterogens:

• Chain 'A':
  Compound: E3 ubiquitin-protein ligase Mdm2
  Species: Homo sapiens [TaxId:9606]
  Gene: MDM2
  Database cross-references and differences (RAF-indexed):
  • Uniprot Q00987
  Domains in SCOPe 2.08: d6q9ha_
• Heterogens: HRH, HOH

PDB Chain Sequences:

• Chain 'A':
  Sequence, based on SEQRES records: (download)
  

  >6q9hA (A:)
  gsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhiv
  ycsndllgdlfgvpsfsvkehrkiytmiyrnlvvvn
  

  
  Sequence, based on observed residues (ATOM records): (download)
  

  >6q9hA (A:)
  ipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycs
  ndllgdlfgvpsfsvkehrkiytmiyrnlvvv