Lineage for d5c5aa_ (5c5a A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321461Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2321462Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2321463Family a.42.1.1: SWIB/MDM2 domain [47593] (5 proteins)
    Pfam PF02201
  6. 2321470Protein MDM2 [47594] (2 species)
  7. 2321488Species Human (Homo sapiens) [TaxId:9606] [47596] (69 PDB entries)
  8. 2321489Domain d5c5aa_: 5c5a A: [318922]
    automated match to d4ereb_
    complexed with cl, iod, nut, so4

Details for d5c5aa_

PDB Entry: 5c5a (more details), 1.15 Å

PDB Description: crystal structure of hdm2 in complex with nutlin-3a
PDB Compounds: (A:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d5c5aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5c5aa_ a.42.1.1 (A:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}
paseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycsn
dllgdlfgvpsfsvkehrkiytmiyrnlvvvn

SCOPe Domain Coordinates for d5c5aa_:

Click to download the PDB-style file with coordinates for d5c5aa_.
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Timeline for d5c5aa_: