Lineage for d4oq3c_ (4oq3 C:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1996222Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 1996223Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 1996224Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 1996231Protein MDM2 [47594] (2 species)
  7. 1996249Species Human (Homo sapiens) [TaxId:9606] [47596] (51 PDB entries)
  8. 1996324Domain d4oq3c_: 4oq3 C: [263324]
    automated match to d3jzra_
    complexed with 2v8

Details for d4oq3c_

PDB Entry: 4oq3 (more details), 2.3 Å

PDB Description: Tetra-substituted imidazoles as a new class of inhibitors of the p53-MDM2 interaction
PDB Compounds: (C:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d4oq3c_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4oq3c_ a.42.1.1 (C:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4oq3c_:

Click to download the PDB-style file with coordinates for d4oq3c_.
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Timeline for d4oq3c_: