Lineage for d3jzsa_ (3jzs A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2321461Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 2321462Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 2321463Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 2321470Protein MDM2 [47594] (2 species)
  7. 2321488Species Human (Homo sapiens) [TaxId:9606] [47596] (60 PDB entries)
  8. 2321497Domain d3jzsa_: 3jzs A: [178936]
    automated match to d1rv1a_
    complexed with edo

Details for d3jzsa_

PDB Entry: 3jzs (more details), 1.78 Å

PDB Description: Human MDM2 liganded with a 12mer peptide inhibitor (pDIQ)
PDB Compounds: (A:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d3jzsa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3jzsa_ a.42.1.1 (A:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}
tlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycsndllgdl
fgvpsfsvkehrkiytmiyrnlv

SCOPe Domain Coordinates for d3jzsa_:

Click to download the PDB-style file with coordinates for d3jzsa_.
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Timeline for d3jzsa_: