PDB entry 4odf

View 4odf on RCSB PDB site
Description: Co-Crystal Structure of MDM2 with Inhibitor Compound 47
Class: ligase/ligase inhibitor
Keywords: p53, protein-protein interaction, ligase-ligase inhibitor complex
Deposited on 2014-01-10, released 2014-04-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-11-22, with a file datestamp of 2017-11-17.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: E3 ubiquitin-protein ligase Mdm2
    Species: Homo sapiens [TaxId:9606]
    Gene: MDM2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4odfa_
  • Heterogens: 2U1, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4odfA (A:)
    msvptdgavttsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkr
    lydekqqhivycsndllgdlfgvpsfsvkehrkiytmiyrnlvvv
    

    Sequence, based on observed residues (ATOM records): (download)
    >4odfA (A:)
    gavttsqipaseqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekq
    qhivycsndllgdlfgvpsfsvkehrkiytmiyrnlvvv