Lineage for d1t4fm_ (1t4f M:)

  1. Root: SCOPe 2.08
  2. Class a: All alpha proteins [46456] (290 folds)
  3. Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. Family a.42.1.1: SWIB/MDM2 domain [47593] (5 proteins)
    Pfam PF02201
  6. Protein MDM2 [47594] (2 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [47596] (76 PDB entries)
  8. Domain d1t4fm_: 1t4f M: [119144]
    automated match to d1rv1a_
    complexed with so4

Details for d1t4fm_

PDB Entry: 1t4f (more details), 1.9 Å

PDB Description: Structure of human MDM2 in complex with an optimized p53 peptide
PDB Compounds: (M:) ubiquitin-protein ligase e3 mdm2

SCOPe Domain Sequences for d1t4fm_:

Sequence; same for both SEQRES and ATOM records: (download)

>d1t4fm_ a.42.1.1 (M:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}
eqetlvrpkplllkllksvgaqkdtytmkevlfylgqyimtkrlydekqqhivycsndll
gdlfgvpsfsvkehrkiytmiyrnlvvv

SCOPe Domain Coordinates for d1t4fm_ are not available.

Timeline for d1t4fm_: