Lineage for d4qocc_ (4qoc C:)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1996222Fold a.42: SWIB/MDM2 domain [47591] (1 superfamily)
    core: 4 helices: open bundle; capped by two small 3-stranded beta-sheets
    duplication: consists of two structural repeats
  4. 1996223Superfamily a.42.1: SWIB/MDM2 domain [47592] (2 families) (S)
    binds to the transactivation domain of human p53
  5. 1996224Family a.42.1.1: SWIB/MDM2 domain [47593] (5 protein domains)
    Pfam PF02201
  6. 1996231Protein MDM2 [47594] (2 species)
  7. 1996249Species Human (Homo sapiens) [TaxId:9606] [47596] (58 PDB entries)
  8. 1996296Domain d4qocc_: 4qoc C: [272373]
    automated match to d1t4ea_
    complexed with 35t

Details for d4qocc_

PDB Entry: 4qoc (more details), 1.7 Å

PDB Description: crystal structure of compound 16 bound to mdm2(17-111), {(3r,5r,6s)-5- (3-chlorophenyl)-6-(4-chlorophenyl)-1-[(1s)-1-cyclopropyl-2- (pyrrolidin-1-ylsulfonyl)ethyl]-3-methyl-2-oxopiperidin-3-yl}acetic acid
PDB Compounds: (C:) E3 ubiquitin-protein ligase Mdm2

SCOPe Domain Sequences for d4qocc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4qocc_ a.42.1.1 (C:) MDM2 {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4qocc_:

Click to download the PDB-style file with coordinates for d4qocc_.
(The format of our PDB-style files is described here.)

Timeline for d4qocc_: