Lineage for Protein: Dihydroorotate dehydrogenase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080000Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2080001Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)
  6. 2080046Protein Dihydroorotate dehydrogenase [51397] (8 species)

Species:

  1. 2080047Escherichia coli [TaxId:562] [82239] (1 PDB entry)
  2. 2080052Human (Homo sapiens) [TaxId:9606] [51400] (43 PDB entries)
    1. Domain for 1d3g:
    2. Domain for 1d3h:
    3. Domain for 2b0m:
    4. Domain for 2fpt:
    5. Domain for 2fpv:
    6. Domain for 2fpy:
    7. Domain for 2fqi:
    8. Domain for 2prh:
    9. Domain for 2prl:
    10. Domain for 2prm:
    11. Domain for 3f1q:
    12. Domain for 3kvj:
    13. Domain for 3kvk:
    14. Domain for 3kvl:
    15. Domain for 3kvm:
    16. Domain for 3u2o:
    17. Domain for 3w7r:
    18. Domain for 3zws:
    19. Domain for 4igh:
    20. Domain for 4jgd:
    21. Domain for 4js3:
    22. Domain for 4jts:
    23. Domain for 4jtt:
    24. Domain for 4jtu:
    25. Domain for 4ls0:
    26. Domain for 4ls1:
    27. Domain for 4ls2:
    28. Domain for 4rk8:
    29. Domain for 4rka:
    30. Domain for 4rli:
    31. Domain for 4rr4:
    32. Domain for 4ylw:
    33. Domain for 4zl1:
    34. Domain for 4zmg:
    35. Domain for 5h2z:
    36. Domain for 5h73:
    37. Domain for 5hin:
    38. Domain for 5hqe:
    39. Domain for 5k9c:
    40. Domain for 5k9d:
    41. Domain for 5mut:
    42. Domain for 5mvc:
    43. Domain for 5mvd:
  3. 2080084Lactococcus lactis, isozyme A [TaxId:1358] [51398] (9 PDB entries)
    1. Domains for 1dor:
      1. 2080095Domain d1dora_: 1dor A: [28595]
        complexed with fmn
      2. 2080096Domain d1dorb_: 1dor B: [28596]
        complexed with fmn
    2. Domains for 1jqv:
      1. 2080099Domain d1jqva_: 1jqv A: [90900]
        complexed with acy, fmn, mg, oro; mutant
      2. 2080100Domain d1jqvb_: 1jqv B: [90901]
        complexed with acy, fmn, mg, oro; mutant
    3. Domains for 1jqx:
      1. 2080087Domain d1jqxa_: 1jqx A: [90902]
        complexed with fmn, gol, mg, oro; mutant
      2. 2080088Domain d1jqxb_: 1jqx B: [90903]
        complexed with fmn, gol, mg, oro; mutant
    4. Domains for 1jrb:
      1. 2080097Domain d1jrba_: 1jrb A: [90904]
        complexed with fmn, oro; mutant
      2. 2080098Domain d1jrbb_: 1jrb B: [90905]
        complexed with fmn, oro; mutant
    5. Domains for 1jrc:
      1. 2080091Domain d1jrca_: 1jrc A: [90906]
        complexed with fmn, oro; mutant
      2. 2080092Domain d1jrcb_: 1jrc B: [90907]
        complexed with fmn, oro; mutant
    6. Domains for 1jub:
      1. 2080085Domain d1juba_: 1jub A: [90908]
        complexed with fmn, gol, mg; mutant
      2. 2080086Domain d1jubb_: 1jub B: [90909]
        complexed with fmn, gol, mg; mutant
    7. Domains for 1jue:
      1. 2080089Domain d1juea_: 1jue A: [90910]
        complexed with acy, fmn, gol, mg
      2. 2080090Domain d1jueb_: 1jue B: [90911]
        complexed with acy, fmn, gol, mg
    8. Domains for 1ovd:
      1. 2080101Domain d1ovda_: 1ovd A: [93593]
        complexed with fmn, gol, mg, oro; mutant
      2. 2080102Domain d1ovdb_: 1ovd B: [93594]
        complexed with fmn, gol, mg, oro; mutant
    9. Domains for 2dor:
      1. 2080093Domain d2dora_: 2dor A: [28593]
        complexed with fmn, oro
      2. 2080094Domain d2dorb_: 2dor B: [28594]
        complexed with fmn, oro
  4. 2080103Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
    PyrD subunit
    1. Domain for 1ep1:
    2. Domain for 1ep2:
    3. Domain for 1ep3:
  5. 2080107Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141759] (1 PDB entry)
    Uniprot Q08210 158-566
    homolog, mitochonrial
  6. 2080109Norway rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
    1. Domains for 1uum:
      1. 2080110Domain d1uuma_: 1uum A: [100010]
        complexed with afi, bog, fmn, oro
      2. 2080111Domain d1uumb_: 1uum B: [100011]
        complexed with afi, bog, fmn, oro
    2. Domain for 1uuo:
  7. 2080113Trypanosoma cruzi [TaxId:353153] [254868] (49 PDB entries)
    1. Domains for 3w1a:
      1. 2080118Domain d3w1aa_: 3w1a A: [229028]
        automated match to d2e68b_
        complexed with fmn, fot, gol, nco
      2. 2080119Domain d3w1ab_: 3w1a B: [233882]
        automated match to d3w1aa_
        complexed with fmn, fot, gol, nco
    2. Domains for 3w1l:
      1. 2080166Domain d3w1la_: 3w1l A: [233884]
        automated match to d3w1aa_
        complexed with fmn, gol, hro, nco
      2. 2080167Domain d3w1lb_: 3w1l B: [233883]
        automated match to d3w1aa_
        complexed with fmn, gol, hro, nco
    3. Domains for 3w1m:
      1. 2080180Domain d3w1ma_: 3w1m A: [233885]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rro
      2. 2080181Domain d3w1mb_: 3w1m B: [233886]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rro
    4. Domains for 3w1n:
      1. 2080198Domain d3w1na_: 3w1n A: [233888]
        automated match to d3w1aa_
        complexed with fmn, gol, iro, nco
      2. 2080199Domain d3w1nb_: 3w1n B: [233887]
        automated match to d3w1aa_
        complexed with fmn, gol, iro, nco
    5. Domains for 3w1p:
      1. 2080194Domain d3w1pa_: 3w1p A: [233889]
        automated match to d3w1aa_
        complexed with ero, fmn, gol, nco
      2. 2080195Domain d3w1pb_: 3w1p B: [233892]
        automated match to d3w1aa_
        complexed with ero, fmn, gol, nco
    6. Domains for 3w1q:
      1. 2080176Domain d3w1qa_: 3w1q A: [233894]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, yro
      2. 2080177Domain d3w1qb_: 3w1q B: [233897]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, yro
    7. Domains for 3w1r:
      1. 2080148Domain d3w1ra_: 3w1r A: [233896]
        automated match to d3w1aa_
        complexed with fmn, gol, mro, nco
      2. 2080149Domain d3w1rb_: 3w1r B: [233898]
        automated match to d3w1aa_
        complexed with fmn, gol, mro, nco
    8. Domains for 3w1t:
      1. 2080158Domain d3w1ta_: 3w1t A: [233899]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, wro
      2. 2080159Domain d3w1tb_: 3w1t B: [233900]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, wro
    9. Domains for 3w1u:
      1. 2080178Domain d3w1ua_: 3w1u A: [233901]
        automated match to d3w1aa_
        complexed with fmn, gol, lro, nco
      2. 2080179Domain d3w1ub_: 3w1u B: [233902]
        automated match to d3w1aa_
        complexed with fmn, gol, lro, nco
    10. Domains for 3w1x:
      1. 2080120Domain d3w1xa_: 3w1x A: [233904]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, xro
      2. 2080121Domain d3w1xb_: 3w1x B: [233905]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, xro
    11. Domains for 3w22:
      1. 2080192Domain d3w22a_: 3w22 A: [233907]
        automated match to d3w1aa_
        complexed with 2ro, fmn, gol, nco
      2. 2080193Domain d3w22b_: 3w22 B: [233909]
        automated match to d3w1aa_
        complexed with 2ro, fmn, gol, nco
    12. Domains for 3w23:
      1. 2080126Domain d3w23a_: 3w23 A: [233908]
        automated match to d3w1aa_
        complexed with 3ro, fmn, gol, nco
      2. 2080127Domain d3w23b_: 3w23 B: [233910]
        automated match to d3w1aa_
        complexed with 3ro, fmn, gol, nco
    13. Domains for 3w2j:
      1. 2080116Domain d3w2ja_: 3w2j A: [233911]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, qro
      2. 2080117Domain d3w2jb_: 3w2j B: [233912]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, qro
    14. Domains for 3w2k:
      1. 2080134Domain d3w2ka_: 3w2k A: [233913]
        automated match to d3w1aa_
        complexed with fmn, gol, kro, nco
      2. 2080135Domain d3w2kb_: 3w2k B: [233915]
        automated match to d3w1aa_
        complexed with fmn, gol, kro, nco
    15. Domains for 3w2l:
      1. 2080150Domain d3w2la_: 3w2l A: [233914]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, vro
      2. 2080151Domain d3w2lb_: 3w2l B: [233916]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, vro
    16. Domains for 3w2m:
      1. 2080142Domain d3w2ma_: 3w2m A: [233917]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, zro
      2. 2080143Domain d3w2mb_: 3w2m B: [233919]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, zro
    17. Domains for 3w2n:
      1. 2080184Domain d3w2na_: 3w2n A: [233920]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rod
      2. 2080185Domain d3w2nb_: 3w2n B: [233918]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rod
    18. Domains for 3w2u:
      1. 2080202Domain d3w2ua_: 3w2u A: [229734]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rou
      2. 2080203Domain d3w2ub_: 3w2u B: [229732]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, rou
    19. Domains for 3w3o:
      1. 2080186Domain d3w3oa_: 3w3o A: [230324]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, roe
      2. 2080187Domain d3w3ob_: 3w3o B: [230325]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, roe
    20. Domains for 3w6y:
      1. 2080208Domain d3w6ya_: 3w6y A: [237472]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w6y
      2. 2080209Domain d3w6yb_: 3w6y B: [237475]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w6y
    21. Domains for 3w70:
      1. 2080206Domain d3w70a_: 3w70 A: [237483]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w70
      2. 2080207Domain d3w70b_: 3w70 B: [237488]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w70
    22. Domains for 3w71:
      1. 2080160Domain d3w71a_: 3w71 A: [237502]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7a
      2. 2080161Domain d3w71b_: 3w71 B: [237498]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7a
    23. Domains for 3w72:
      1. 2080138Domain d3w72a_: 3w72 A: [237476]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7b
      2. 2080139Domain d3w72b_: 3w72 B: [237482]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7b
    24. Domains for 3w73:
      1. 2080170Domain d3w73a_: 3w73 A: [237493]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w73
      2. 2080171Domain d3w73b_: 3w73 B: [237497]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w73
    25. Domains for 3w74:
      1. 2080188Domain d3w74a_: 3w74 A: [237495]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w74
      2. 2080189Domain d3w74b_: 3w74 B: [237496]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w74
    26. Domains for 3w75:
      1. 2080124Domain d3w75a_: 3w75 A: [237477]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w75
      2. 2080125Domain d3w75b_: 3w75 B: [237473]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w75
    27. Domains for 3w76:
      1. 2080144Domain d3w76a_: 3w76 A: [237487]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w76
      2. 2080145Domain d3w76b_: 3w76 B: [237485]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w76
    28. Domains for 3w7c:
      1. 2080168Domain d3w7ca_: 3w7c A: [237486]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7c
      2. 2080169Domain d3w7cb_: 3w7c B: [237490]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7c
    29. Domains for 3w7d:
      1. 2080132Domain d3w7da_: 3w7d A: [237510]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7d
      2. 2080133Domain d3w7db_: 3w7d B: [237509]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7d
    30. Domains for 3w7e:
      1. 2080140Domain d3w7ea_: 3w7e A: [237479]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7f
      2. 2080141Domain d3w7eb_: 3w7e B: [237484]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7f
    31. Domains for 3w7g:
      1. 2080136Domain d3w7ga_: 3w7g A: [237500]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7g
      2. 2080137Domain d3w7gb_: 3w7g B: [237505]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7g
    32. Domains for 3w7h:
      1. 2080154Domain d3w7ha_: 3w7h A: [237515]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7h
      2. 2080155Domain d3w7hb_: 3w7h B: [237514]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7h
    33. Domains for 3w7i:
      1. 2080162Domain d3w7ia_: 3w7i A: [237489]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7i
      2. 2080163Domain d3w7ib_: 3w7i B: [237494]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7i
    34. Domains for 3w7j:
      1. 2080146Domain d3w7ja_: 3w7j A: [237480]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7j
      2. 2080147Domain d3w7jb_: 3w7j B: [237481]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7j
    35. Domains for 3w7k:
      1. 2080152Domain d3w7ka_: 3w7k A: [237513]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7k
      2. 2080153Domain d3w7kb_: 3w7k B: [237512]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7k
    36. Domains for 3w7l:
      1. 2080174Domain d3w7la_: 3w7l A: [237478]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7l
      2. 2080175Domain d3w7lb_: 3w7l B: [237474]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7l
    37. Domains for 3w7m:
      1. 2080200Domain d3w7ma_: 3w7m A: [237499]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7m
      2. 2080201Domain d3w7mb_: 3w7m B: [237503]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7m
    38. Domains for 3w7n:
      1. 2080204Domain d3w7na_: 3w7n A: [237491]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7n
      2. 2080205Domain d3w7nb_: 3w7n B: [237492]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7n
    39. Domains for 3w7o:
      1. 2080156Domain d3w7oa_: 3w7o A: [237506]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7o
      2. 2080157Domain d3w7ob_: 3w7o B: [237504]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7o
    40. Domains for 3w7p:
      1. 2080164Domain d3w7pa_: 3w7p A: [237508]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7p
      2. 2080165Domain d3w7pb_: 3w7p B: [237511]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7p
    41. Domains for 3w7q:
      1. 2080172Domain d3w7qa_: 3w7q A: [237507]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7q
      2. 2080173Domain d3w7qb_: 3w7q B: [237501]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w7q
    42. Domains for 3w83:
      1. 2080210Domain d3w83a_: 3w83 A: [238509]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w83
      2. 2080211Domain d3w83b_: 3w83 B: [238510]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w83
    43. Domains for 3w84:
      1. 2080196Domain d3w84a_: 3w84 A: [237734]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w8z
      2. 2080197Domain d3w84b_: 3w84 B: [237733]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w8z
    44. Domains for 3w85:
      1. 2080190Domain d3w85a_: 3w85 A: [237735]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w85
      2. 2080191Domain d3w85b_: 3w85 B: [237737]
        automated match to d3w1aa_
        complexed with fmn, gol, nco, w85
    45. Domains for 3w86:
      1. 2080130Domain d3w86a_: 3w86 A: [237736]
        automated match to d3w1aa_
        complexed with cac, edo, fmn, gol, nco, w86
      2. 2080131Domain d3w86b_: 3w86 B: [237732]
        automated match to d3w1aa_
        complexed with cac, edo, fmn, gol, nco, w86
    46. Domains for 3w87:
      1. 2080122Domain d3w87a1: 3w87 A:0-312 [238511]
        Other proteins in same PDB: d3w87a2, d3w87b2
        automated match to d3w88a_
        complexed with cac, edo, fmn, gol, nco, peg, w87
      2. 2080123Domain d3w87b1: 3w87 B:0-312 [238512]
        Other proteins in same PDB: d3w87a2, d3w87b2
        automated match to d3w88a_
        complexed with cac, edo, fmn, gol, nco, peg, w87
    47. Domains for 3w88:
      1. 2080114Domain d3w88a1: 3w88 A:0-312 [237739]
        Other proteins in same PDB: d3w88a2, d3w88b2
        automated match to d3c61a_
        complexed with cac, edo, fmn, gol, nco, peg, w88
      2. 2080115Domain d3w88b1: 3w88 B:0-312 [262353]
        Other proteins in same PDB: d3w88a2, d3w88b2
        automated match to d3w88a_
        complexed with cac, edo, fmn, gol, nco, peg, w88
    48. Domains for 4jd4:
      1. 2080128Domain d4jd4a_: 4jd4 A: [237164]
        automated match to d3w1aa_
        complexed with fmn, gol, jdm, nco
      2. 2080129Domain d4jd4b_: 4jd4 B: [237162]
        automated match to d3w1aa_
        complexed with fmn, gol, jdm, nco
    49. Domains for 4jdb:
      1. 2080182Domain d4jdba_: 4jdb A: [237166]
        automated match to d3w1aa_
        complexed with fmn, gol, jdb, nco
      2. 2080183Domain d4jdbb_: 4jdb B: [237163]
        automated match to d3w1aa_
        complexed with fmn, gol, jdb, nco
  8. 2080212Trypanosome (Trypanosoma brucei) [TaxId:5691] [141758] (1 PDB entry)
    Uniprot Q57U83 2-313

More info for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases

Timeline for Protein Dihydroorotate dehydrogenase from c.1.4.1: FMN-linked oxidoreductases: