PDB entry 3zws

View 3zws on RCSB PDB site
Description: Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor
Class: oxidoreductase
Keywords: oxidoreductase
Deposited on 2011-08-02, released 2012-06-27
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-07-11, with a file datestamp of 2012-07-06.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.16171
AEROSPACI score: 0.61 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d3zwsa_
  • Heterogens: FMN, ORO, SO4, CL, AVQ, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >3zwsA (A:)
    matgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfr
    npvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygf
    nshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladyl
    vvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedia
    svvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvp
    iigvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtda
    igadhrr
    

    Sequence, based on observed residues (ATOM records): (download)
    >3zwsA (A:)
    hlmptlqglldpesahrlavrftslgllarfqdsdmlevrvlghkfrnpvgiaagfdkhg
    eavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvvehrlr
    arqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntaglr
    slqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidgliv
    tnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgqda
    lekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr