Lineage for d3zwsa_ (3zws A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080000Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2080001Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)
  6. 2080046Protein Dihydroorotate dehydrogenase [51397] (8 species)
  7. 2080052Species Human (Homo sapiens) [TaxId:9606] [51400] (43 PDB entries)
  8. 2080054Domain d3zwsa_: 3zws A: [218549]
    automated match to d1d3ga_
    complexed with act, avq, cl, fmn, oro, so4

Details for d3zwsa_

PDB Entry: 3zws (more details), 1.6 Å

PDB Description: Structure of Human Dihydroorotate Dehydrogenase with a Bound Inhibitor
PDB Compounds: (A:) Dihydroorotate dehydrogenase (quinone), mitochondrial

SCOPe Domain Sequences for d3zwsa_:

Sequence, based on SEQRES records: (download)

>d3zwsa_ c.1.4.1 (A:) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
hlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpvgiaagfdk
hgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvvehr
lrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntag
lrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidgl
ivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgq
dalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

Sequence, based on observed residues (ATOM records): (download)

>d3zwsa_ c.1.4.1 (A:) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
hlmptlqglldpesahrlavrftslgllarfqdsdmlevrvlghkfrnpvgiaagfdkhg
eavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvvehrlr
arqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvsspntaglr
slqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidgliv
tnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgqda
lekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

SCOPe Domain Coordinates for d3zwsa_:

Click to download the PDB-style file with coordinates for d3zwsa_.
(The format of our PDB-style files is described here.)

Timeline for d3zwsa_: