Lineage for d6cjfa1 (6cjf A:33-396)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2414849Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2414850Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)
  6. 2414895Protein Dihydroorotate dehydrogenase [51397] (8 species)
  7. 2414901Species Human (Homo sapiens) [TaxId:9606] [51400] (52 PDB entries)
  8. 3052354Domain d6cjfa1: 6cjf A:33-396 [352416]
    Other proteins in same PDB: d6cjfa2, d6cjfb2
    automated match to d3kvma_
    complexed with f54, fmn, oro, zwi

Details for d6cjfa1

PDB Entry: 6cjf (more details), 1.63 Å

PDB Description: human dihydroorotate dehydrogenase bound to 4-quinoline carboxylic acid inhibitor 43
PDB Compounds: (A:) Dihydroorotate dehydrogenase (quinone), mitochondrial

SCOPe Domain Sequences for d6cjfa1:

Sequence, based on SEQRES records: (download)

>d6cjfa1 c.1.4.1 (A:33-396) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
dhrr

Sequence, based on observed residues (ATOM records): (download)

>d6cjfa1 c.1.4.1 (A:33-396) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllqdsdmlevrvlghkfrnpvgiaag
fdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshglsvv
ehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvgkae
lrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelgidglivtnttvsr
paglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggvssgqdalekirag
aslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr

SCOPe Domain Coordinates for d6cjfa1:

Click to download the PDB-style file with coordinates for d6cjfa1.
(The format of our PDB-style files is described here.)

Timeline for d6cjfa1:

  • d6cjfa1 appears in periodic updates to SCOPe 2.07 starting on 2018-05-24

View in 3D
Domains from same chain:
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d6cjfa2