PDB entry 7k2u

View 7k2u on RCSB PDB site
Description: dhodh in complex with ligand 13
Class: oxidoreductase
Keywords: dihydroorotate dehydrogenase, dhodh, oxidoreductase, inhibitor
Deposited on 2020-09-09, released 2020-10-21
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-10-21, with a file datestamp of 2020-10-16.
Experiment type: XRAY
Resolution: 1.73 Å
R-factor: N/A
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DHODH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d7k2ua_
  • Heterogens: VU7, FMN, ORO, ACT, SO4, GOL, PGE, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >7k2uA (A:)
gamatgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghk
frnpvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinry
gfnshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgplad
ylvvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdked
iasvvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgr
vpiigvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvt
daigadhrr

    Sequence, based on observed residues (ATOM records): (download) 
    >7k2uA (A:)
atgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrn
pvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfn
shglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylv
vnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedias
vvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpi
igvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdai
gadhrr