PDB entry 5h73

View 5h73 on RCSB PDB site
Description: Crystal structure of human DHODH with 18F
Class: oxidoreductase/inhibitor
Keywords: Dihydroorotate dehydrogenase, OXIDOREDUCTASE-INHIBITOR complex
Deposited on 2016-11-16, released 2017-07-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-07-26, with a file datestamp of 2017-07-21.
Experiment type: XRAY
Resolution: 1.58 Å
R-factor: N/A
AEROSPACI score: 0.45 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DHODH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d5h73a_
  • Heterogens: 7L7, FMN, ORO, SO4, ACT, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >5h73A (A:)
    mghhhhhhhhhhssghiddddkhmatgderfyaehlmptlqglldpesahrlavrftslg
    llprarfqdsdmlevrvlghkfrnpvgiaagfdkhgeavdglykmgfgfveigsvtpkpq
    egnprprvfrlpedqavinrygfnshglsvvehrlrarqqkqakltedglplgvnlgknk
    tsvdaaedyaegvrvlgpladylvvnvsspntaglrslqgkaelrrlltkvlqerdglrr
    vhrpavlvkiapdltsqdkediasvvkelgidglivtnttvsrpaglqgalrsetgglsg
    kplrdlstqtiremyaltqgrvpiigvggvssgqdalekiragaslvqlytaltfwgppv
    vgkvkreleallkeqgfggvtdaigadhrr
    

    Sequence, based on observed residues (ATOM records): (download)
    >5h73A (A:)
    gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
    giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
    glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
    vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
    kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
    vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
    dhr