PDB entry 4jts

View 4jts on RCSB PDB site
Description: Crystal structure of human dihydroorotate dehydrogenase (DHODH) with 072
Class: oxidoreductase
Keywords: DHODH, oxidoreductase, FMN binding, mitochondria inner membrane
Deposited on 2013-03-24, released 2014-03-26
The last revision prior to the SCOPe 2.07 freeze date was dated 2014-03-26, with a file datestamp of 2014-03-21.
Experiment type: XRAY
Resolution: 2.21 Å
R-factor: 0.157
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DHODH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d4jtsa_
  • Heterogens: FMN, ORO, SO4, ACT, JTS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >4jtsA (A:)
    mghhhhhhhhhhssghiddddkhmatgderfyaehlmptlqglldpesahrlavrftslg
    llprarfqdsdmlevrvlghkfrnpvgiaagfdkhgeavdglykmgfgfveigsvtpkpq
    egnprprvfrlpedqavinrygfnshglsvvehrlrarqqkqakltedglplgvnlgknk
    tsvdaaedyaegvrvlgpladylvvnvsspntaglrslqgkaelrrlltkvlqerdglrr
    vhrpavlvkiapdltsqdkediasvvkelgidglivtnttvsrpaglqgalrsetgglsg
    kplrdlstqtiremyaltqgrvpiigvggvssgqdalekiragaslvqlytaltfwgppv
    vgkvkreleallkeqgfggvtdaigadhrr
    

    Sequence, based on observed residues (ATOM records): (download)
    >4jtsA (A:)
    tgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnp
    vgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfns
    hglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvv
    nvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasv
    vkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpii
    gvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaig
    adhrr