Lineage for d2b0ma_ (2b0m A:)

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 proteins)
  6. Protein Dihydroorotate dehydrogenase [51397] (8 species)
  7. Species Human (Homo sapiens) [TaxId:9606] [51400] (69 PDB entries)
  8. Domain d2b0ma_: 2b0m A: [127644]
    automated match to d1d3ga_
    complexed with 201, fmn, oro

    has additional subdomain(s) that are not in the common domain
    has additional insertions and/or extensions that are not grouped together

Details for d2b0ma_

PDB Entry: 2b0m (more details), 2 Å

PDB Description: Human dihydroorotate dehydrogenase bound to a novel inhibitor
PDB Compounds: (A:) Dihydroorotate dehydrogenase, mitochondrial

SCOPe Domain Sequences for d2b0ma_:

Sequence, based on SEQRES records: (download)

>d2b0ma_ c.1.4.1 (A:) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
dhrr

Sequence, based on observed residues (ATOM records): (download)

>d2b0ma_ c.1.4.1 (A:) Dihydroorotate dehydrogenase {Human (Homo sapiens) [TaxId: 9606]}
gderfyaehlmptlqglldpesahrlavrftslgllpfqdsdmlevrvlghkfrnpvgia
agfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnshgls
vvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvnvss
pntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkel
gidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvgg
vssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhr
r

SCOPe Domain Coordinates for d2b0ma_ are not available.

Timeline for d2b0ma_: