Lineage for Family c.1.4.1: FMN-linked oxidoreductases

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2080000Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2080001Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)

Protein Domains:

  1. 2080002(S)-3-O-geranylgeranylglyceryl phosphate synthase [141765] (1 species)
  2. 208000812-oxophytodienoate reductase (OPR, OYE homolog) [63896] (3 species)
    1. 2080009Species Thale cress (Arabidopsis thaliana), OPR1 [TaxId:3702] [102040] (1 PDB entry)
      At1G76680
    2. 2080011Species Thale cress (Arabidopsis thaliana), OPR3 [TaxId:3702] [102041] (2 PDB entries)
    3. 2080016Species Tomato (Lycopersicon esculentum), OPR1 [TaxId:4081] [63897] (4 PDB entries)
  3. 20800252,4-dienoyl-CoA reductase, N-terminal domain [102042] (1 species)
  4. 2080028Alpha subunit of glutamate synthase, central and FMN domains [69381] (2 species)
    Central domain (residues 423-780) may be a rudiment form of the FMN domain
    1. 2080029Species Azospirillum brasilense [TaxId:192] [69382] (2 PDB entries)
    2. 2080038Species Synechocystis sp. [TaxId:1143] [75055] (5 PDB entries)
  5. 2080046Dihydroorotate dehydrogenase [51397] (8 species)
    1. 2080047Species Escherichia coli [TaxId:562] [82239] (1 PDB entry)
    2. 2080052Species Human (Homo sapiens) [TaxId:9606] [51400] (43 PDB entries)
    3. 2080084Species Lactococcus lactis, isozyme A [TaxId:1358] [51398] (9 PDB entries)
    4. 2080103Species Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
      PyrD subunit
    5. 2080107Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141759] (1 PDB entry)
      Uniprot Q08210 158-566
      homolog, mitochonrial
    6. 2080109Species Norway rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
    7. 2080113Species Trypanosoma cruzi [TaxId:353153] [254868] (49 PDB entries)
    8. 2080212Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [141758] (1 PDB entry)
      Uniprot Q57U83 2-313
  6. 2080214Dihydropyrimidine dehydrogenase, domain 4 [51410] (1 species)
  7. 2080236Flavocytochrome b2, C-terminal domain [51408] (1 species)
  8. 2080260Glycolate oxidase [51404] (1 species)
  9. 2080267Hydroxyacid oxidase [141761] (1 species)
  10. 2080270Isopentenyl-diphosphate delta-isomerase [89454] (3 species)
    1. 2080271Species Bacillus subtilis [TaxId:1423] [89455] (2 PDB entries)
    2. 2080276Species Thermus thermophilus HB8 [TaxId:300852] [159377] (1 PDB entry)
    3. 2080281Species Thermus thermophilus [TaxId:274] [141760] (1 PDB entry)
      Uniprot Q53W52 23-332
  11. 2080284Membrane-associated (S)-mandelate dehydrogenase [63898] (1 species)
  12. 2080289Morphinone reductase [75053] (1 species)
  13. 2080294NADPH dehydrogenase NamA [141763] (1 species)
    OYE homolog
  14. 2080304Old yellow enzyme (OYE) [51401] (2 species)
    1. 2080305Species Lager yeast (Saccharomyces pastorianus) [TaxId:27292] [51402] (20 PDB entries)
    2. 2080324Species Yeast (Candida albicans) [TaxId:5476] [51403] (2 PDB entries)
  15. 2080327PcrB protein homolog YerE [102046] (2 species)
    provisional classification; it is not known whether this protein binds FMN or not
    1. 2080328Species Bacillus subtilis [TaxId:1423] [102047] (5 PDB entries)
    2. 2080339Species Staphylococcus aureus [TaxId:418127] [194170] (2 PDB entries)
  16. 2080344Pentaerythritol tetranirate reductase [63900] (1 species)
  17. 2080374Putative flavin oxidoreducatase TM0096 [102044] (1 species)
    Dihydrouridine synthase (Dus) homologue; contains extra C-terminal alpha-helical domain
  18. 2080377Trimethylamine dehydrogenase, N-terminal domain [51406] (1 species)
    two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold
  19. 2080389automated matches [190228] (18 species)
    not a true protein
    1. 2080390Species Geobacillus kaustophilus [TaxId:235909] [257133] (2 PDB entries)
    2. 2080395Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)
    3. 2080404Species Kluyveromyces marxianus [TaxId:4911] [311442] (2 PDB entries)
    4. 2080413Species Lactococcus lactis [TaxId:1358] [186992] (3 PDB entries)
    5. 2080418Species Leishmania braziliensis [TaxId:5660] [272759] (1 PDB entry)
    6. 2080421Species Leishmania donovani [TaxId:5661] [188354] (1 PDB entry)
    7. 2080426Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)
    8. 2080433Species Leishmania major [TaxId:5664] [255853] (6 PDB entries)
    9. 2080446Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [256645] (7 PDB entries)
    10. 2080458Species Norway rat (Rattus norvegicus) [TaxId:10116] [195883] (2 PDB entries)
    11. 2080463Species Plasmodium falciparum [TaxId:36329] [189697] (5 PDB entries)
    12. 2080469Species Pseudomonas putida [TaxId:303] [225091] (4 PDB entries)
    13. 2080474Species Solanum lycopersicum [TaxId:4081] [187823] (5 PDB entries)
    14. 2080485Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [187180] (2 PDB entries)
    15. 2080489Species Thermus thermophilus [TaxId:274] [254915] (1 PDB entry)
    16. 2080494Species Trypanosoma cruzi [TaxId:5693] [187324] (7 PDB entries)
    17. 2280849Species Trypanosoma cruzi [TaxId:353153] [324150] (2 PDB entries)
    18. 2295383Species Lactococcus lactis [TaxId:1360] [338684] (1 PDB entry)

More info for Family c.1.4.1: FMN-linked oxidoreductases

Timeline for Family c.1.4.1: FMN-linked oxidoreductases: