Lineage for Family c.1.4.1: FMN-linked oxidoreductases

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2414849Superfamily c.1.4: FMN-linked oxidoreductases [51395] (2 families) (S)
  5. 2414850Family c.1.4.1: FMN-linked oxidoreductases [51396] (19 protein domains)

Protein Domains:

  1. 2414851(S)-3-O-geranylgeranylglyceryl phosphate synthase [141765] (1 species)
  2. 241485712-oxophytodienoate reductase (OPR, OYE homolog) [63896] (3 species)
    1. 2414858Species Thale cress (Arabidopsis thaliana), OPR1 [TaxId:3702] [102040] (1 PDB entry)
      At1G76680
    2. 2414860Species Thale cress (Arabidopsis thaliana), OPR3 [TaxId:3702] [102041] (2 PDB entries)
    3. 2414865Species Tomato (Lycopersicon esculentum), OPR1 [TaxId:4081] [63897] (4 PDB entries)
  3. 24148742,4-dienoyl-CoA reductase, N-terminal domain [102042] (1 species)
  4. 2414877Alpha subunit of glutamate synthase, central and FMN domains [69381] (2 species)
    Central domain (residues 423-780) may be a rudiment form of the FMN domain
    1. 2414878Species Azospirillum brasilense [TaxId:192] [69382] (2 PDB entries)
    2. 2414887Species Synechocystis sp. [TaxId:1143] [75055] (5 PDB entries)
  5. 2414895Dihydroorotate dehydrogenase [51397] (8 species)
    1. 2414896Species Escherichia coli [TaxId:562] [82239] (1 PDB entry)
    2. 2414901Species Human (Homo sapiens) [TaxId:9606] [51400] (52 PDB entries)
    3. 2414945Species Lactococcus lactis, isozyme A [TaxId:1358] [51398] (9 PDB entries)
    4. 2414964Species Lactococcus lactis, isozyme B [TaxId:1358] [51399] (3 PDB entries)
      PyrD subunit
    5. 2414968Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [141759] (1 PDB entry)
      Uniprot Q08210 158-566
      homolog, mitochonrial
    6. 2414970Species Norway rat (Rattus norvegicus) [TaxId:10116] [102039] (2 PDB entries)
    7. 2414974Species Trypanosoma cruzi [TaxId:353153] [254868] (49 PDB entries)
    8. 2415073Species Trypanosome (Trypanosoma brucei) [TaxId:5691] [141758] (1 PDB entry)
      Uniprot Q57U83 2-313
  6. 2415075Dihydropyrimidine dehydrogenase, domain 4 [51410] (1 species)
  7. 2415097Flavocytochrome b2, C-terminal domain [51408] (1 species)
  8. 2415121Glycolate oxidase [51404] (1 species)
  9. 2415128Hydroxyacid oxidase [141761] (1 species)
  10. 2415131Isopentenyl-diphosphate delta-isomerase [89454] (3 species)
    1. 2415132Species Bacillus subtilis [TaxId:1423] [89455] (2 PDB entries)
    2. 2415137Species Thermus thermophilus HB8 [TaxId:300852] [159377] (1 PDB entry)
    3. 2415142Species Thermus thermophilus [TaxId:274] [141760] (1 PDB entry)
      Uniprot Q53W52 23-332
  11. 2415145Membrane-associated (S)-mandelate dehydrogenase [63898] (1 species)
  12. 2415150Morphinone reductase [75053] (1 species)
  13. 2415155NADPH dehydrogenase NamA [141763] (1 species)
    OYE homolog
  14. 2415165Old yellow enzyme (OYE) [51401] (2 species)
    1. 2415166Species Lager yeast (Saccharomyces pastorianus) [TaxId:27292] [51402] (20 PDB entries)
    2. 2415187Species Yeast (Candida albicans) [TaxId:5476] [51403] (2 PDB entries)
  15. 2415190PcrB protein homolog YerE [102046] (2 species)
    provisional classification; it is not known whether this protein binds FMN or not
    1. 2415191Species Bacillus subtilis [TaxId:1423] [102047] (5 PDB entries)
    2. 2415202Species Staphylococcus aureus [TaxId:418127] [194170] (2 PDB entries)
  16. 2415207Pentaerythritol tetranirate reductase [63900] (1 species)
  17. 2415239Putative flavin oxidoreducatase TM0096 [102044] (1 species)
    Dihydrouridine synthase (Dus) homologue; contains extra C-terminal alpha-helical domain
  18. 2415242Trimethylamine dehydrogenase, N-terminal domain [51406] (1 species)
    two other domains are alpha/beta Rossmann-like fold and beta/beta/alpha fold
  19. 2415254automated matches [190228] (19 species)
    not a true protein
    1. 2415255Species Geobacillus kaustophilus [TaxId:235909] [257133] (2 PDB entries)
    2. 2415260Species Human (Homo sapiens) [TaxId:9606] [187000] (8 PDB entries)
    3. 2415269Species Kluyveromyces marxianus [TaxId:4911] [311442] (2 PDB entries)
    4. 2415278Species Lactococcus lactis [TaxId:1358] [186992] (3 PDB entries)
    5. 2415285Species Lactococcus lactis [TaxId:1360] [338684] (1 PDB entry)
    6. 2415288Species Leishmania braziliensis [TaxId:5660] [272759] (1 PDB entry)
    7. 2415291Species Leishmania donovani [TaxId:5661] [188354] (1 PDB entry)
    8. 2415296Species Leishmania major [TaxId:347515] [255968] (3 PDB entries)
    9. 2415303Species Leishmania major [TaxId:5664] [255853] (6 PDB entries)
    10. 2415316Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [256645] (7 PDB entries)
    11. 2415328Species Norway rat (Rattus norvegicus) [TaxId:10116] [195883] (2 PDB entries)
    12. 2415333Species Plasmodium falciparum [TaxId:36329] [189697] (5 PDB entries)
    13. 2415339Species Pseudomonas putida [TaxId:303] [225091] (5 PDB entries)
    14. 2415344Species Solanum lycopersicum [TaxId:4081] [187823] (5 PDB entries)
    15. 2415355Species Thale cress (Arabidopsis thaliana) [TaxId:3702] [187180] (2 PDB entries)
    16. 2415359Species Thermus thermophilus [TaxId:274] [254915] (1 PDB entry)
    17. 2415364Species Trypanosoma cruzi [TaxId:353153] [324150] (2 PDB entries)
    18. 2415369Species Trypanosoma cruzi [TaxId:5693] [187324] (7 PDB entries)
    19. 3047766Species Saccharomyces cerevisiae [TaxId:559292] [347828] (2 PDB entries)

More info for Family c.1.4.1: FMN-linked oxidoreductases

Timeline for Family c.1.4.1: FMN-linked oxidoreductases: