PDB entry 1d3g

View 1d3g on RCSB PDB site
Description: human dihydroorotate dehydrogenase complexed with brequinar analog
Class: oxidoreductase
Keywords: protein-antiproliferative agent complex, oxidoreductase
Deposited on 1999-09-29, released 2000-09-13
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.168
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: dihydroorotate dehydrogenase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1d3ga_
  • Heterogens: SO4, ACT, BRE, FMN, ORO, DDQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1d3gA (A:)
    matgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfr
    npvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygf
    nshglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladyl
    vvnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedia
    svvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvp
    iigvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtda
    igadhrr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1d3gA (A:)
    matgderfyaehlmptlqglldpesahrlavrftslgllpfqdsdmlevrvlghkfrnpv
    giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
    glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
    vsspntaglgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvvkelg
    idglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiigvggv
    ssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaigadhrr