PDB entry 6jmd

View 6jmd on RCSB PDB site
Description: Crystal structure of human DHODH in complex with inhibitor 1223
Class: oxidoreductase/oxidoreductase inhibitor
Keywords: DHODH, Inhibitor, Complex, OXIDOREDUCTASE, OXIDOREDUCTASE-OXIDOREDUCTASE INHIBITOR complex
Deposited on 2019-03-08, released 2020-03-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-09-30, with a file datestamp of 2020-09-25.
Experiment type: XRAY
Resolution: 1.78 Å
R-factor: N/A
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dihydroorotate dehydrogenase (quinone), mitochondrial
    Species: Homo sapiens [TaxId:9606]
    Gene: DHODH
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6jmda_
  • Heterogens: BVO, FMN, ORO, SO4, ACT, LDA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6jmdA (A:)
atgderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrn
pvgiaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfn
shglsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylv
vnvsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkedias
vvkelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpi
igvggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdai
gadhrr

    Sequence, based on observed residues (ATOM records): (download) 
    >6jmdA (A:)
gderfyaehlmptlqglldpesahrlavrftslgllprarfqdsdmlevrvlghkfrnpv
giaagfdkhgeavdglykmgfgfveigsvtpkpqegnprprvfrlpedqavinrygfnsh
glsvvehrlrarqqkqakltedglplgvnlgknktsvdaaedyaegvrvlgpladylvvn
vsspntaglrslqgkaelrrlltkvlqerdglrrvhrpavlvkiapdltsqdkediasvv
kelgidglivtnttvsrpaglqgalrsetgglsgkplrdlstqtiremyaltqgrvpiig
vggvssgqdalekiragaslvqlytaltfwgppvvgkvkreleallkeqgfggvtdaiga
dhr