Lineage for Protein: Ribonuclease A (also ribonuclease B, S)

  1. Root: SCOPe 2.06
  2. 2152203Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2155703Fold d.5: RNase A-like [54075] (1 superfamily)
    contains long curved beta-sheet and 3 helices
  4. 2155704Superfamily d.5.1: RNase A-like [54076] (2 families) (S)
    can be classified as disulfide-rich
  5. 2155705Family d.5.1.1: Ribonuclease A-like [54077] (9 protein domains)
  6. 2155814Protein Ribonuclease A (also ribonuclease B, S) [54078] (3 species)

Species:

  1. 2155815Cow (Bos taurus) [TaxId:9913] [54079] (188 PDB entries)
    1. Domains for 1a2w:
      1. 2155976Domain d1a2wa_: 1a2w A: [37248]
        3d domain-swapped dimer
        complexed with cl, so4
      2. 2155977Domain d1a2wb_: 1a2w B: [37249]
        3d domain-swapped dimer
        complexed with cl, so4
    2. Domain for 1a5p:
    3. Domain for 1a5q:
    4. Domains for 1afk:
      1. 2155892Domain d1afka_: 1afk A: [37199]
        complexed with pap
      2. 2155893Domain d1afkb_: 1afk B: [37200]
        complexed with pap
    5. Domains for 1afl:
      1. 2155902Domain d1afla_: 1afl A: [37208]
        complexed with atr, cit
      2. 2155903Domain d1aflb_: 1afl B: [37209]
        complexed with atr, cit
    6. Domains for 1afu:
      1. 2155971Domain d1afua_: 1afu A: [37244]
      2. 2155972Domain d1afub_: 1afu B: [37245]
    7. Domain for 1aqp:
    8. Domain for 1bel:
    9. Domains for 1bzq:
      1. 2156041Domain d1bzqa_: 1bzq A: [37270]
        Other proteins in same PDB: d1bzqk_, d1bzql_, d1bzqm_, d1bzqn_
        protein/RNA complex; complexed with po4
      2. 2156042Domain d1bzqb_: 1bzq B: [37271]
        Other proteins in same PDB: d1bzqk_, d1bzql_, d1bzqm_, d1bzqn_
        protein/RNA complex; complexed with po4
      3. 2156043Domain d1bzqc_: 1bzq C: [37272]
        Other proteins in same PDB: d1bzqk_, d1bzql_, d1bzqm_, d1bzqn_
        protein/RNA complex; complexed with po4
      4. 2156044Domain d1bzqd_: 1bzq D: [37273]
        Other proteins in same PDB: d1bzqk_, d1bzql_, d1bzqm_, d1bzqn_
        protein/RNA complex; complexed with po4
    10. Domain for 1c0b:
    11. Domain for 1c0c:
    12. Domain for 1c8w:
    13. Domain for 1c9v:
    14. Domain for 1c9x:
    15. Domain for 1cjq:
    16. Domain for 1cjr:
    17. Domain for 1d5d:
    18. Domain for 1d5e:
    19. Domain for 1d5h:
    20. Domain for 1dfj:
    21. Domains for 1dy5:
      1. 2155816Domain d1dy5a_: 1dy5 A: [37163]
        deamidated derivative
        complexed with act, ipa, so4
      2. 2155817Domain d1dy5b_: 1dy5 B: [37164]
        deamidated derivative
        complexed with act, ipa, so4
    22. Domain for 1eic:
    23. Domain for 1eid:
    24. Domain for 1eie:
    25. Domains for 1eos:
      1. 2155957Domain d1eosa_: 1eos A: [37237]
        complexed with u2g
      2. 2155958Domain d1eosb_: 1eos B: [37238]
        complexed with u2g
    26. Domain for 1eow:
    27. Domains for 1f0v:
      1. 2155878Domain d1f0va_: 1f0v A: [37190]
        a new type of 3d domain swapping
        protein/DNA complex; complexed with gol, po4
      2. 2155879Domain d1f0vb_: 1f0v B: [37191]
        a new type of 3d domain swapping
        protein/DNA complex; complexed with gol, po4
      3. 2155880Domain d1f0vc_: 1f0v C: [37192]
        a new type of 3d domain swapping
        protein/DNA complex; complexed with gol, po4
      4. 2155881Domain d1f0vd_: 1f0v D: [37193]
        a new type of 3d domain swapping
        protein/DNA complex; complexed with gol, po4
    28. Domain for 1fev:
      • 2156008Domain d1fev.1: 1fev A:,B: [37254]
        chemical Ala 4 to Aib 'mutation'
        complexed with so4; mutant
    29. Domain for 1fs3:
    30. Domain for 1izp:
    31. Domain for 1izq:
    32. Domain for 1izr:
    33. Domain for 1j7z:
    34. Domain for 1j80:
    35. Domain for 1j81:
    36. Domain for 1j82:
    37. Domains for 1jn4:
      1. 2155963Domain d1jn4a_: 1jn4 A: [84179]
        complexed with 139
      2. 2155964Domain d1jn4b_: 1jn4 B: [84180]
        complexed with 139
    38. Domains for 1js0:
      1. 2155996Domain d1js0a_: 1js0 A: [71831]
        domain-swapped minor trimer
        complexed with so4
      2. 2155997Domain d1js0b_: 1js0 B: [71832]
        domain-swapped minor trimer
        complexed with so4
      3. 2155998Domain d1js0c_: 1js0 C: [71833]
        domain-swapped minor trimer
        complexed with so4
    39. Domains for 1jvt:
      1. 2155949Domain d1jvta_: 1jvt A: [71901]
      2. 2155950Domain d1jvtb_: 1jvt B: [71902]
    40. Domains for 1jvu:
      1. 2155922Domain d1jvua_: 1jvu A: [71903]
        complexed with c2p
      2. 2155923Domain d1jvub_: 1jvu B: [71904]
        complexed with c2p
    41. Domains for 1jvv:
      1. 2155992Domain d1jvva_: 1jvv A: [71905]
      2. 2155993Domain d1jvvb_: 1jvv B: [71906]
    42. Domain for 1kf2:
    43. Domain for 1kf3:
    44. Domain for 1kf4:
    45. Domain for 1kf5:
    46. Domain for 1kf7:
    47. Domain for 1kf8:
    48. Domain for 1kh8:
    49. Domains for 1lsq:
      1. 2155906Domain d1lsqa_: 1lsq A: [37211]
        ASN 67 replaced by a beta-aspartyl residue
        complexed with so4
      2. 2155907Domain d1lsqb_: 1lsq B: [37212]
        ASN 67 replaced by a beta-aspartyl residue
        complexed with so4
    50. Domains for 1o0f:
      1. 2155866Domain d1o0fa_: 1o0f A: [92395]
        protein/RNA complex; complexed with a3p
      2. 2155867Domain d1o0fb_: 1o0f B: [92396]
        protein/RNA complex; complexed with a3p
    51. Domains for 1o0h:
      1. 2155825Domain d1o0ha_: 1o0h A: [92397]
        complexed with adp
      2. 2155826Domain d1o0hb_: 1o0h B: [92398]
        complexed with adp
    52. Domains for 1o0m:
      1. 2155853Domain d1o0ma_: 1o0m A: [92399]
        complexed with u2p
      2. 2155854Domain d1o0mb_: 1o0m B: [92400]
        complexed with u2p
    53. Domains for 1o0n:
      1. 2155859Domain d1o0na_: 1o0n A: [92401]
        complexed with u3p
      2. 2155860Domain d1o0nb_: 1o0n B: [92402]
        complexed with u3p
    54. Domains for 1o0o:
      1. 2155827Domain d1o0oa_: 1o0o A: [92403]
        complexed with a2p
      2. 2155828Domain d1o0ob_: 1o0o B: [92404]
        complexed with a2p
    55. Domains for 1qhc:
      1. 2155912Domain d1qhca_: 1qhc A: [37215]
        complexed with pua
      2. 2155913Domain d1qhcb_: 1qhc B: [37216]
        complexed with pua
    56. Domain for 1rar:
    57. Domain for 1ras:
    58. Domain for 1rat:
    59. Domains for 1rbb:
      1. 2156039Domain d1rbba_: 1rbb A: [37268]
      2. 2156040Domain d1rbbb_: 1rbb B: [37269]
    60. Domain for 1rbc:
    61. Domain for 1rbd:
    62. Domain for 1rbe:
    63. Domain for 1rbf:
    64. Domain for 1rbg:
    65. Domain for 1rbh:
    66. Domain for 1rbi:
    67. Domain for 1rbj:
    68. Domain for 1rbn:
    69. Domain for 1rbw:
    70. Domain for 1rbx:
    71. Domain for 1rca:
    72. Domain for 1rcn:
    73. Domain for 1rha:
    74. Domain for 1rhb:
    75. Domain for 1rnc:
    76. Domain for 1rnd:
    77. Domain for 1rnm:
    78. Domain for 1rnn:
    79. Domain for 1rno:
    80. Domain for 1rnq:
    81. Domain for 1rnu:
    82. Domain for 1rnv:
    83. Domain for 1rnw:
    84. Domain for 1rnx:
    85. Domain for 1rny:
    86. Domain for 1rnz:
    87. Domain for 1rob:
    88. Domain for 1rpf:
    89. Domain for 1rpg:
    90. Domain for 1rph:
    91. Domain for 1rsm:
    92. Domain for 1rta:
    93. Domain for 1rtb:
    94. Domain for 1ruv:
    95. Domain for 1srn:
    96. Domain for 1ssa:
    97. Domain for 1ssb:
    98. Domain for 1ssc:
    99. Domains for 1xps:
      1. 2155896Domain d1xpsa_: 1xps A: [37202]
      2. 2155897Domain d1xpsb_: 1xps B: [37203]
    100. Domains for 1xpt:
      1. 2155930Domain d1xpta_: 1xpt A: [37219]
      2. 2155931Domain d1xptb_: 1xpt B: [37220]
    101. Domain for 1ymn:
    102. Domain for 1ymr:
    103. Domain for 1ymw:
    104. Domain for 1z3l:
    105. Domain for 1z3m:
    106. Domain for 1z3p:
    107. Domain for 2aas:
    108. Domain for 2apq:
    109. Domain for 2rat:
    110. Domain for 2rln:
    111. Domain for 2rns:
    112. Domain for 3dh5:
    113. Domain for 3dh6:
    114. Domain for 3di7:
    115. Domain for 3di8:
    116. Domain for 3di9:
    117. Domain for 3dib:
    118. Domain for 3dic:
    119. Domains for 3fkz:
      1. 2155974Domain d3fkza_: 3fkz A: [175863]
        automated match to d1a2wa_
        mutant
      2. 2155975Domain d3fkzb_: 3fkz B: [175864]
        automated match to d1kf2a_
        mutant
    120. Domains for 3fl0:
      1. 2155936Domain d3fl0a_: 3fl0 A: [175865]
        automated match to d1a2wa_
        complexed with cgp; mutant
      2. 2155937Domain d3fl0b_: 3fl0 B: [175866]
        automated match to d1a2wa_
        complexed with cgp; mutant
    121. Domains for 3fl1:
      1. 2155940Domain d3fl1a_: 3fl1 A: [175867]
        automated match to d1a2wa_
        complexed with cgp, so4, tre; mutant
      2. 2155941Domain d3fl1b_: 3fl1 B: [175868]
        automated match to d1a2wa_
        complexed with cgp, so4, tre; mutant
    122. Domains for 3fl3:
      1. 2155857Domain d3fl3a_: 3fl3 A: [175869]
        automated match to d1a2wa_
        complexed with tre; mutant
      2. 2155858Domain d3fl3b_: 3fl3 B: [175870]
        automated match to d1a2wa_
        complexed with tre; mutant
    123. Domain for 3ql1:
    124. Domains for 3ql2:
      1. 2155873Domain d3ql2a_: 3ql2 A: [200360]
        automated match to d3ql2b_
        complexed with so4
      2. 2155874Domain d3ql2b_: 3ql2 B: [195951]
        automated match to d1kf3a_
        complexed with so4
    125. Domain for 3rat:
    126. Domain for 3rh1:
    127. Domains for 3rid:
      1. 2155979Domain d3rida_: 3rid A: [215830]
        automated match to d3rh1a_
        complexed with cgp, po4
      2. 2155980Domain d3ridb_: 3rid B: [215831]
        automated match to d3rh1a_
        complexed with cgp, po4
      3. 2155981Domain d3ridc_: 3rid C: [215832]
        automated match to d3rh1a_
        complexed with cgp, po4
      4. 2155982Domain d3ridd_: 3rid D: [215833]
        automated match to d3rh1a_
        complexed with cgp, po4
    128. Domain for 3rn3:
    129. Domain for 3rsd:
    130. Domain for 3rsk:
    131. Domain for 3rsp:
    132. Domain for 3srn:
    133. Domain for 4ao1:
    134. Domains for 4g8v:
      1. 2155884Domain d4g8va_: 4g8v A: [192544]
        automated match to d1kf3a_
        complexed with 0ey
      2. 2155885Domain d4g8vb_: 4g8v B: [192547]
        automated match to d1kf3a_
        complexed with 0ey
    135. Domains for 4g8y:
      1. 2155917Domain d4g8ya_: 4g8y A: [192546]
        automated match to d1kf3a_
        complexed with 0ft
      2. 2155918Domain d4g8yb_: 4g8y B: [192543]
        automated match to d1kf3a_
        complexed with 0ft
    136. Domains for 4g90:
      1. 2155927Domain d4g90a_: 4g90 A: [192545]
        automated match to d1kf3a_
        complexed with 0g0
      2. 2155928Domain d4g90b_: 4g90 B: [192832]
        automated match to d1kf3a_
        complexed with 0g0
    137. Domain for 4j5z:
    138. Domain for 4j60:
    139. Domain for 4j61:
    140. Domain for 4j62:
    141. Domain for 4j63:
    142. Domain for 4j64:
    143. Domain for 4j65:
    144. Domain for 4j66:
    145. Domain for 4j67:
    146. Domain for 4j68:
    147. Domain for 4j69:
    148. Domain for 4j6a:
    149. Domains for 4l55:
      1. 2155942Domain d4l55a_: 4l55 A: [236441]
        automated match to d1kf3a_
        complexed with ru
      2. 2155943Domain d4l55b_: 4l55 B: [236440]
        automated match to d1kf3a_
        complexed with ru
    150. Domains for 4mxf:
      1. 2156027Domain d4mxfa_: 4mxf A: [230158]
        automated match to d1kf3a_
        protein/RNA complex; complexed with au
      2. 2156028Domain d4mxfb_: 4mxf B: [230157]
        automated match to d1kf3a_
        protein/RNA complex; complexed with au
    151. Domain for 4ooh:
    152. Domains for 4ot4:
      1. 2155987Domain d4ot4a_: 4ot4 A: [258046]
        automated match to d1kf3a_
        complexed with cpt
      2. 2155988Domain d4ot4b_: 4ot4 B: [258047]
        automated match to d1kf3a_
        complexed with cpt
    153. Domains for 4peq:
      1. 2156021Domain d4peqa_: 4peq A: [257494]
        Other proteins in same PDB: d4peqb_, d4peqd_
        automated match to d1kf3a_
      2. 2156022Domain d4peqc_: 4peq C: [257493]
        Other proteins in same PDB: d4peqb_, d4peqd_
        automated match to d1kf3a_
    154. Domain for 4pou:
    155. Domains for 4qh3:
      1. 2156018Domain d4qh3a_: 4qh3 A: [258362]
        automated match to d1kf3a_
        complexed with i83
      2. 2156019Domain d4qh3b_: 4qh3 B: [258363]
        automated match to d1kf3a_
        complexed with i83
    156. Domain for 4rat:
    157. Domain for 4rsd:
    158. Domain for 4rsk:
    159. Domain for 4rte:
    160. Domains for 4s0q:
      1. 2156031Domain d4s0qa_: 4s0q A: [279490]
        automated match to d1kf3a_
        protein/RNA complex; complexed with qpt
      2. 2156032Domain d4s0qb_: 4s0q B: [279489]
        automated match to d1kf3a_
        protein/RNA complex; complexed with qpt
    161. Domains for 4s18:
      1. 2156034Domain d4s18a_: 4s18 A: [279635]
        automated match to d1kf3a_
        complexed with 1pt
      2. 2156035Domain d4s18b_: 4s18 B: [279634]
        automated match to d1kf3a_
        complexed with 1pt
    162. Domain for 4srn:
    163. Domains for 4wyn:
      1. 2156006Domain d4wyna_: 4wyn A: [279505]
        automated match to d1kf3a_
        mutant
      2. 2156007Domain d4wynb_: 4wyn B: [279504]
        automated match to d1kf3a_
        mutant
    164. Domains for 4wyp:
      1. 2155933Domain d4wypa_: 4wyp A: [279506]
        automated match to d1kf3a_
        complexed with amp; mutant
      2. 2155934Domain d4wypb_: 4wyp B: [279509]
        automated match to d1kf3a_
        complexed with amp; mutant
    165. Domains for 4wyz:
      1. 2155909Domain d4wyza_: 4wyz A: [279502]
        automated match to d1kf3a_
        complexed with u3p; mutant
      2. 2155910Domain d4wyzb_: 4wyz B: [279507]
        automated match to d1kf3a_
        complexed with u3p; mutant
    166. Domain for 4zz4:
    167. Domain for 5d6u:
    168. Domain for 5d97:
    169. Domains for 5e5e:
      1. 2156025Domain d5e5ea_: 5e5e A: [279820]
        automated match to d1kf3a_
        complexed with dms, pt
      2. 2156026Domain d5e5eb_: 5e5e B: [279821]
        automated match to d1kf3a_
        complexed with dms, pt
    170. Domains for 5e5f:
      1. 2155990Domain d5e5fa_: 5e5f A: [279822]
        automated match to d1kf3a_
        complexed with act, au, so4
      2. 2155991Domain d5e5fb_: 5e5f B: [279825]
        automated match to d1kf3a_
        complexed with act, au, so4
    171. Domains for 5et4:
      1. 2283310Domain d5et4c_: 5et4 C: [326611]
        automated match to d1kf3a_
        complexed with c3p, mpd
      2. 2283382Domain d5et4b_: 5et4 B: [326683]
        automated match to d1kf3a_
        complexed with c3p, mpd
      3. 2283404Domain d5et4a_: 5et4 A: [326705]
        automated match to d1kf3a_
        complexed with c3p, mpd
      4. 2283466Domain d5et4d_: 5et4 D: [326767]
        automated match to d1kf3a_
        complexed with c3p, mpd
    172. Domains for 5jlg:
      1. 2277068Domain d5jlga_: 5jlg A: [320369]
        automated match to d1kf3a_
        complexed with 6l6, dms, ru
      2. 2277107Domain d5jlgb_: 5jlg B: [320408]
        automated match to d1kf3a_
        complexed with 6l6, dms, ru
    173. Domains for 5jmg:
      1. 2276826Domain d5jmgb_: 5jmg B: [320127]
        automated match to d1kf3a_
        complexed with cl, cmo, ir
      2. 2276853Domain d5jmga_: 5jmg A: [320154]
        automated match to d1kf3a_
        complexed with cl, cmo, ir
    174. Domains for 5jml:
      1. 2276818Domain d5jmlb_: 5jml B: [320119]
        automated match to d1kf3a_
        complexed with cl, cmo, ir, o
      2. 2276938Domain d5jmla_: 5jml A: [320239]
        automated match to d1kf3a_
        complexed with cl, cmo, ir, o
    175. Domain for 5na9:
    176. Domains for 5obc:
      1. 2293733Domain d5obcb_: 5obc B: [337034]
        automated match to d1kf3a_
        complexed with 9q8, po4, ru2
      2. 2293747Domain d5obca_: 5obc A: [337048]
        automated match to d1kf3a_
        complexed with 9q8, po4, ru2
    177. Domains for 5obd:
      1. 2293741Domain d5obdb_: 5obd B: [337042]
        automated match to d1kf3a_
        complexed with 9q8, po4
      2. 2293844Domain d5obda_: 5obd A: [337145]
        automated match to d1kf3a_
        complexed with 9q8, po4
    178. Domains for 5obe:
      1. 2293795Domain d5obeb_: 5obe B: [337096]
        automated match to d1kf3a_
        complexed with 9q8, po4, ru2
      2. 2293797Domain d5obea_: 5obe A: [337098]
        automated match to d1kf3a_
        complexed with 9q8, po4, ru2
    179. Domain for 5rat:
    180. Domain for 5rsa:
    181. Domain for 6rat:
    182. Domain for 6rsa:
    183. Domain for 7rat:
    184. Domain for 7rsa:
    185. Domain for 8rat:
    186. Domains for 8rsa:
      1. 2155899Domain d8rsaa_: 8rsa A: [37205]
        complexed with adt
      2. 2155900Domain d8rsab_: 8rsa B: [37206]
        complexed with adt
    187. Domain for 9rat:
    188. Domains for 9rsa:
      1. 2155919Domain d9rsaa_: 9rsa A: [37221]
        complexed with adu
      2. 2155920Domain d9rsab_: 9rsa B: [37222]
        complexed with adu
  2. 2156046Human (Homo sapiens), des1-7 [TaxId:9606] [54080] (8 PDB entries)
    1. Domains for 1dza:
      1. 2156061Domain d1dzaa_: 1dza A: [37275]
        designed cytotoxic mutant
      2. 2156062Domain d1dzab_: 1dza B: [37276]
        designed cytotoxic mutant
    2. Domain for 1e21:
    3. Domains for 1h8x:
      1. 2156052Domain d1h8xa_: 1h8x A: [65739]
        domain-swapped dimer
      2. 2156053Domain d1h8xb_: 1h8x B: [65740]
        domain-swapped dimer
    4. Domains for 1z7x:
      1. 2156049Domain d1z7xx_: 1z7x X: [124676]
        Other proteins in same PDB: d1z7xw_, d1z7xy_
        automated match to d1dzaa_
        complexed with cit
      2. 2156050Domain d1z7xz_: 1z7x Z: [124678]
        Other proteins in same PDB: d1z7xw_, d1z7xy_
        automated match to d1dzaa_
        complexed with cit
    5. Domain for 2k11:
    6. Domains for 2q4g:
      1. 2156047Domain d2q4gx_: 2q4g X: [139850]
        Other proteins in same PDB: d2q4gw_, d2q4gy_
        automated match to d1dzaa_
        complexed with cit
      2. 2156048Domain d2q4gz_: 2q4g Z: [139852]
        Other proteins in same PDB: d2q4gw_, d2q4gy_
        automated match to d1dzaa_
        complexed with cit
    7. Domains for 3f8g:
      1. 2156054Domain d3f8ga_: 3f8g A: [175568]
        automated match to d1dzaa_
        complexed with so4
      2. 2156055Domain d3f8gb_: 3f8g B: [175569]
        automated match to d1dzaa_
        complexed with so4
    8. Domains for 4kxh:
      1. 2156056Domain d4kxha_: 4kxh A: [228069]
        automated match to d2q4gx_
        complexed with cl, na, so4
      2. 2156057Domain d4kxhb_: 4kxh B: [235240]
        automated match to d4kxha_
        complexed with cl, na, so4
      3. 2156058Domain d4kxhc_: 4kxh C: [235241]
        automated match to d4kxha_
        complexed with cl, na, so4
      4. 2156059Domain d4kxhd_: 4kxh D: [228070]
        automated match to d2q4gx_
        complexed with cl, na, so4
  3. 2156063Norway rat (Rattus norvegicus) [TaxId:10116] [54081] (1 PDB entry)

More info for Protein Ribonuclease A (also ribonuclease B, S) from d.5.1.1: Ribonuclease A-like

Timeline for Protein Ribonuclease A (also ribonuclease B, S) from d.5.1.1: Ribonuclease A-like: