PDB entry 4wyp

View 4wyp on RCSB PDB site
Description: The crystal structure of the A109G mutant of RNase A in complex with 5'AMP
Class: hydrolase
Keywords: conformational dynamics, HYDROLASE
Deposited on 2014-11-17, released 2015-11-18
The last revision prior to the SCOPe 2.08 freeze date was dated 2019-12-25, with a file datestamp of 2019-12-20.
Experiment type: XRAY
Resolution: 1.5 Å
R-factor: N/A
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Gene: RNASE1, RNS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61823 (1-124)
      • engineered mutation (109)
    Domains in SCOPe 2.08: d4wypa_
  • Chain 'B':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Gene: RNASE1, RNS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61823 (1-124)
      • initiating methionine (0)
      • engineered mutation (109)
    Domains in SCOPe 2.08: d4wypb_
  • Heterogens: AMP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >4wypA (A:)
mketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcs
qknvackngqtncyqsystmsitdcretgsskypncaykttqankhiivgcegnpyvpvh
fdasv

    Sequence, based on observed residues (ATOM records): (download) 
    >4wypA (A:)
ketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcsq
knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivgcegnpyvpvhf
dasv

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >4wypB (B:)
mketaaakferqhmdsstsaasssnycnqmmksrnltkdrckpvntfvhesladvqavcs
qknvackngqtncyqsystmsitdcretgsskypncaykttqankhiivgcegnpyvpvh
fdasv