PDB entry 3fl3

View 3fl3 on RCSB PDB site
Description: X-ray structure of the ligand free non covalent swapped form of the A19P/Q28L/K31C/S32C mutant of bovine pancreatic ribonuclease
Class: hydrolase
Keywords: 3D-domain swapping, bovine seminal ribonuclease, non-covalent dimer, antitumor activity, quaternary structure flexibility, protein mutations and evolution, Endonuclease, Glycation, Glycoprotein, Hydrolase, Nuclease, Secreted
Deposited on 2008-12-18, released 2009-03-24
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-07-04.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: N/A
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Gene: RNASE1, RNS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61823 (0-123)
      • engineered (27)
      • engineered (30-31)
    Domains in SCOPe 2.08: d3fl3a_
  • Chain 'B':
    Compound: ribonuclease pancreatic
    Species: Bos taurus [TaxId:9913]
    Gene: RNASE1, RNS1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P61823 (0-123)
      • engineered (18)
      • engineered (27)
      • engineered (30-31)
    Domains in SCOPe 2.08: d3fl3b_
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >3fl3A (A:)
ketaaakferqhmdsstspasssnycnlmmccrnltkdrckpvntfvhesladvqavcsq
knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhf
dasv

    Sequence, based on observed residues (ATOM records): (download) 
    >3fl3A (A:)
ketaaakferqhmdsstsssnycnlmmccrnltkdrckpvntfvhesladvqavcsqknv
ackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhfdas
v

  • Chain 'B':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >3fl3B (B:)
ketaaakferqhmdsstspasssnycnlmmccrnltkdrckpvntfvhesladvqavcsq
knvackngqtncyqsystmsitdcretgsskypncaykttqankhiivacegnpyvpvhf
dasv