SCOPe 2.08: Protein: Coagulation factor VIIa

Lineage for Protein: Coagulation factor VIIa

Root: SCOPe 2.08
Class b: All beta proteins [48724] (180 folds)
Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
barrel, closed; n=6, S=8; greek-key
duplication: consists of two domains of the same fold
Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)
Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)
Protein Coagulation factor VIIa [50550] (1 species)

Species:

Human (Homo sapiens) [TaxId:9606] [50551] (90 PDB entries)
Uniprot P08709 213-466 ! Uniprot P08709 213-446
1. Domain for 1cvw:
  - Domain d1cvwh_: 1cvw H: [26293]
    Other proteins in same PDB: d1cvwl_
    complexed with 0ge, ca
2. Domain for 1dan:
  - Domain d1danh_: 1dan H: [26292]
    Other proteins in same PDB: d1dan.1, d1danl1, d1danl2, d1danl3, d1danu1
    complexed with 0z6, bgc, ca, cac, cl, fuc
3. Domains for 1dva:
  1. Domain d1dvah_: 1dva H: [26296]
    Other proteins in same PDB: d1dval1, d1dval2, d1dvam1, d1dvam2
    complexed with 0z6, ca, cac, fuc, ful, glc
  2. Domain d1dvai_: 1dva I: [26297]
    Other proteins in same PDB: d1dval1, d1dval2, d1dvam1, d1dvam2
    complexed with 0z6, ca, cac, fuc, ful, glc
4. Domain for 1fak:
  - Domain d1fakh_: 1fak H: [26294]
    Other proteins in same PDB: d1faki_, d1fakl1, d1fakl2, d1fakl3, d1fakt1, d1fakt2
    complexed with ca, fuc, glc; mutant
5. Domain for 1j9c:
  - Domain d1j9ch_: 1j9c H: [103841]
    Other proteins in same PDB: d1j9cl1, d1j9cl2, d1j9ct1, d1j9ct2
    complexed with 0z6, ca, ful, glc, nag
6. Domain for 1jbu:
  - Domain d1jbuh_: 1jbu H: [62856]
    Other proteins in same PDB: d1jbul_
    complexed with ben, so4
7. Domain for 1kli:
  - Domain d1klih_: 1kli H: [77435]
    Other proteins in same PDB: d1klil_
    complexed with ben, ca, gol, so4
8. Domain for 1klj:
  - Domain d1kljh_: 1klj H: [77437]
    Other proteins in same PDB: d1kljl_
    complexed with ca, edo
9. Domain for 1o5d:
  - Domain d1o5dh_: 1o5d H: [103880]
    Other proteins in same PDB: d1o5dl1, d1o5dl2, d1o5dt1, d1o5dt2
    complexed with cr9
10. Domain for 1qfk:
  - Domain d1qfkh_: 1qfk H: [26295]
    Other proteins in same PDB: d1qfkl1, d1qfkl2
    complexed with 0z6, ca, fuc, glc
11. Domain for 1ygc:
  - Domain d1ygch_: 1ygc H: [123142]
    Other proteins in same PDB: d1ygcl_
    automated match to d1cvwh_
    complexed with 905, ca, so4
12. Domain for 1z6j:
  - Domain d1z6jh_: 1z6j H: [124523]
    Other proteins in same PDB: d1z6jl1, d1z6jl2, d1z6jl3, d1z6jt1, d1z6jt2
    automated match to d1cvwh_
    complexed with ca, mg, py3
13. Domain for 2a2q:
  - Domain d2a2qh_: 2a2q H: [126052]
    Other proteins in same PDB: d2a2ql1, d2a2ql2, d2a2ql3, d2a2qt1, d2a2qt2
    automated match to d1cvwh_
    complexed with ca, cl, fuc, glc, mg, na, pbz, zn
14. Domain for 2aei:
  - Domain d2aeih_: 2aei H: [126631]
    Other proteins in same PDB: d2aeil1, d2aeil2, d2aeil3, d2aeit1, d2aeit2
    automated match to d1cvwh_
    complexed with 03r, ca, cac
15. Domain for 2b7d:
  - Domain d2b7dh_: 2b7d H: [128033]
    Other proteins in same PDB: d2b7dl1, d2b7dl2, d2b7dt1, d2b7dt2
    automated match to d1cvwh_
    complexed with c1b
16. Domain for 2b8o:
  - Domain d2b8oh_: 2b8o H: [128095]
    Other proteins in same PDB: d2b8ol1, d2b8ol2, d2b8ol3, d2b8ot1, d2b8ot2
    automated match to d1cvwh_
    complexed with 0gj, ca, cl, fuc, glc, mg, na, zn
17. Domain for 2c4f:
  - Domain d2c4fh1: 2c4f H:16-257 [129805]
    Other proteins in same PDB: d2c4fl1, d2c4fl2, d2c4fl3, d2c4fu1
    automatically matched to d1cvwh_
    complexed with ca, fuc, gil, glc, nag
18. Domain for 2f9b:
  - Domain d2f9bh_: 2f9b H: [133155]
    Other proteins in same PDB: d2f9bl1, d2f9bl2, d2f9bt1, d2f9bt2
    automated match to d1cvwh_
    complexed with n1h
19. Domain for 2fir:
  - Domain d2firh_: 2fir H: [133531]
    Other proteins in same PDB: d2firl1, d2firl2, d2firl3, d2firt1, d2firt2
    automated match to d1cvwh_
    complexed with 0g7, ca, cl, fuc, glc, mg, na, zn
20. Domain for 2flb:
  - Domain d2flbh_: 2flb H: [133710]
    Other proteins in same PDB: d2flbl1, d2flbl2, d2flbt1, d2flbt2
    automated match to d1cvwh_
    complexed with 6nh
21. Domain for 2flr:
  - Domain d2flrh_: 2flr H: [133747]
    Other proteins in same PDB: d2flrl1, d2flrl2, d2flrt1, d2flrt2
    automated match to d1cvwh_
    complexed with 7nh
22. Domain for 2pmm:
  - Domain d2pmmh_: 2pmm H: [408172]
    Other proteins in same PDB: d2pmml1, d2pmml2
    automated match to d1cvwh_
    complexed with ca, ch2, fuc, glc
23. Domain for 2puq:
  - Domain d2puqh_: 2puq H: [139751]
    Other proteins in same PDB: d2puql1, d2puql2
    automated match to d1cvwh_
    complexed with bgc, ca, fuc
24. Domain for 2zp0:
  - Domain d2zp0h_: 2zp0 H: [154744]
    Other proteins in same PDB: d2zp0l1, d2zp0l2, d2zp0l3, d2zp0t1, d2zp0t2
    automated match to d1cvwh_
    complexed with bgc, ca, fuc, pi0
25. Domain for 2zwl:
  - Domain d2zwlh_: 2zwl H: [171562]
    Other proteins in same PDB: d2zwll1, d2zwll2, d2zwll3
    automated match to d1cvwh_
    complexed with 567, bgc, ca, fuc
26. Domain for 2zzu:
  - Domain d2zzuh_: 2zzu H: [171617]
    Other proteins in same PDB: d2zzul1, d2zzul2, d2zzul3
    automated match to d1cvwh_
    complexed with 359, bgc, ca, fuc
27. Domain for 3ela:
  - Domain d3elah_: 3ela H: [175051]
    Other proteins in same PDB: d3elal1, d3elal2
    automated match to d1cvwh_
    complexed with 0z6, ca, fuc, glc; mutant
28. Domain for 3th2:
  - Domain d3th2h_: 3th2 H: [192144]
    Other proteins in same PDB: d3th2l1, d3th2l2, d3th2l3, d3th2t1, d3th2t2
    automated match to d1klih_
    complexed with ben, bgc, ca, cl, fuc, mg, na
29. Domain for 3th3:
  - Domain d3th3h_: 3th3 H: [192145]
    Other proteins in same PDB: d3th3l1, d3th3l2, d3th3t1, d3th3t2
    automated match to d1klih_
    complexed with 0ge, bgc, ca, cl, fuc
30. Domain for 3th4:
  - Domain d3th4h_: 3th4 H: [192146]
    Other proteins in same PDB: d3th4l1, d3th4l2, d3th4l3, d3th4t1, d3th4t2
    automated match to d1klih_
    complexed with 0ge, bgc, ca, cl, fuc, mg, na
31. Domain for 4ish:
  - Domain d4ishh_: 4ish H: [192911]
    Other proteins in same PDB: d4ishl_
    automated match to d1klih_
    complexed with 1ge, ca
32. Domain for 4isi:
  - Domain d4isih_: 4isi H: [192896]
    Other proteins in same PDB: d4isil_
    automated match to d1klih_
    complexed with 1gg, ca
33. Domain for 4jyu:
  - Domain d4jyuh_: 4jyu H: [227558]
    Other proteins in same PDB: d4jyul_
    automated match to d1klih_
    complexed with 1ok, ca, gol, so4
34. Domain for 4jyv:
  - Domain d4jyvh_: 4jyv H: [227555]
    Other proteins in same PDB: d4jyvl_
    automated match to d1klih_
    complexed with 1oj, ca, gol, so4
35. Domain for 4jzd:
  - Domain d4jzdh_: 4jzd H: [227609]
    Other proteins in same PDB: d4jzdl_
    automated match to d1klih_
    complexed with 1nj, ca, gol, so4
36. Domain for 4jze:
  - Domain d4jzeh_: 4jze H: [227608]
    Other proteins in same PDB: d4jzel_
    automated match to d1klih_
    complexed with 1nk, ca, gol, so4
37. Domain for 4jzf:
  - Domain d4jzfh_: 4jzf H: [227611]
    Other proteins in same PDB: d4jzfl_
    automated match to d1klih_
    complexed with 1nl, ca, gol, so4
38. Domain for 4na9:
  - Domain d4na9h_: 4na9 H: [236814]
    Other proteins in same PDB: d4na9l_
    automated match to d1klih_
    complexed with 1t7, ca
39. Domain for 4ng9:
  - Domain d4ng9h_: 4ng9 H: [235904]
    Other proteins in same PDB: d4ng9l_
    automated match to d1klih_
    complexed with 2ke, ca, gol, so4
40. Domain for 4nga:
  - Domain d4ngah_: 4nga H: [235903]
    Other proteins in same PDB: d4ngal_
    automated match to d1klih_
    complexed with 2kf, ca, gol, so4
41. Domain for 4x8s:
  - Domain d4x8sh_: 4x8s H: [270831]
    Other proteins in same PDB: d4x8sl_
    automated match to d1klih_
    complexed with 3z7, ca, gol, so4
42. Domain for 4x8t:
  - Domain d4x8th_: 4x8t H: [270834]
    Other proteins in same PDB: d4x8tl_
    automated match to d1klih_
    complexed with 3z8, ca, gol, so4
43. Domain for 4x8u:
  - Domain d4x8uh_: 4x8u H: [270833]
    Other proteins in same PDB: d4x8ul_
    automated match to d1klih_
    complexed with 3zb, ca, gol, so4
44. Domain for 4x8v:
  - Domain d4x8vh_: 4x8v H: [270832]
    Other proteins in same PDB: d4x8vl_
    automated match to d1klih_
    complexed with 3z9, ca, gol, so4
45. Domain for 4ylq:
  - Domain d4ylqh_: 4ylq H: [280180]
    Other proteins in same PDB: d4ylql1, d4ylql2, d4ylql3, d4ylqt1, d4ylqt2
    automated match to d4jzeh_
    complexed with 0z7, ca, fuc, pol, tma
46. Domain for 4yt6:
  - Domain d4yt6h_: 4yt6 H: [272083]
    Other proteins in same PDB: d4yt6l_
    automated match to d1klih_
    complexed with 4jy, ca, gol, so4
47. Domain for 4yt7:
  - Domain d4yt7h_: 4yt7 H: [272084]
    Other proteins in same PDB: d4yt7l_
    automated match to d1klih_
    complexed with 4k1, ca, gol, so4
48. Domain for 4z6a:
  - Domain d4z6ah_: 4z6a H: [280181]
    Other proteins in same PDB: d4z6al1, d4z6al2
    automated match to d4jzeh_
    complexed with 0z6, bgc, ca, cit, fuc
49. Domain for 4zma:
  - Domain d4zmah_: 4zma H: [280194]
    Other proteins in same PDB: d4zmal1, d4zmal2, d4zmal3, d4zmat1, d4zmat2
    automated match to d4jzeh_
    complexed with 0z6, bgc, ca, cac, fuc
50. Domain for 4zxx:
  - Domain d4zxxh_: 4zxx H: [275320]
    Other proteins in same PDB: d4zxxl_
    automated match to d1klih_
    complexed with 4t0, ca, so4
51. Domain for 4zxy:
  - Domain d4zxyh_: 4zxy H: [275321]
    Other proteins in same PDB: d4zxyl_
    automated match to d1klih_
    complexed with 4t1, ca, gol, so4
52. Domain for 5i46:
  - Domain d5i46h_: 5i46 H: [318810]
    Other proteins in same PDB: d5i46l_
    automated match to d1klih_
    complexed with 67o, ca, mes, so4
53. Domain for 5l2y:
  - Domain d5l2yh_: 5l2y H: [323436]
    Other proteins in same PDB: d5l2yl_
    automated match to d1klih_
    complexed with 70d, ca, gol, so4
54. Domain for 5l2z:
  - Domain d5l2zh_: 5l2z H: [323491]
    Other proteins in same PDB: d5l2zl_
    automated match to d1klih_
    complexed with 70c, ca, gol, so4
55. Domain for 5l30:
  - Domain d5l30h_: 5l30 H: [323430]
    Other proteins in same PDB: d5l30l_
    automated match to d1klih_
    complexed with 70a, ca, gol, so4
56. Domain for 5pa8:
  - Domain d5pa8c_: 5pa8 C: [335701]
    Other proteins in same PDB: d5pa8a_
    automated match to d1klih_
    complexed with ca, cl, gol, hai, so4
57. Domain for 5pa9:
  - Domain d5pa9c_: 5pa9 C: [335804]
    Other proteins in same PDB: d5pa9a_
    automated match to d1klih_
    complexed with abn, ca, cl, gol, so4
58. Domain for 5paa:
  - Domain d5paac_: 5paa C: [335763]
    Other proteins in same PDB: d5paaa_
    automated match to d1klih_
    complexed with amc, ca, cl, gol, so4
59. Domain for 5pab:
  - Domain d5pabh_: 5pab H: [335805]
    Other proteins in same PDB: d5pabl_
    automated match to d1klih_
    complexed with 7xd, ca, cl, gol, so4
60. Domain for 5pac:
  - Domain d5pacb_: 5pac B: [335755]
    Other proteins in same PDB: d5paca_
    automated match to d1klih_
    complexed with 7y7, ca, cl, gol, so4
61. Domain for 5pae:
  - Domain d5paeb_: 5pae B: [335782]
    Other proteins in same PDB: d5paea_
    automated match to d1klih_
    complexed with 7ya, ca, gol, so4
62. Domain for 5paf:
  - Domain d5pafb_: 5paf B: [335709]
    Other proteins in same PDB: d5pafa_
    automated match to d1klih_
    complexed with 7lr, ca, cl, gol, so4, tfa
63. Domain for 5pag:
  - Domain d5pagb_: 5pag B: [335798]
    Other proteins in same PDB: d5paga_
    automated match to d1klih_
    complexed with 7yj, ca, cl, gol, so4
64. Domain for 5pai:
  - Domain d5paib_: 5pai B: [335734]
    Other proteins in same PDB: d5paia_
    automated match to d1klih_
    complexed with 7ym, ca, cl, gol, so4
65. Domain for 5paj:
  - Domain d5pajb_: 5paj B: [335695]
    Other proteins in same PDB: d5paja_
    automated match to d1klih_
    complexed with 7xj, ca, cl, so4
66. Domain for 5pak:
  - Domain d5pakc_: 5pak C: [335799]
    Other proteins in same PDB: d5paka_
    automated match to d1klih_
    complexed with 7yp, ca, so4
67. Domain for 5pam:
  - Domain d5pamb_: 5pam B: [335803]
    Other proteins in same PDB: d5pama_
    automated match to d1klih_
    complexed with 7z1, ca, cl, gol, so4
68. Domain for 5pan:
  - Domain d5panb_: 5pan B: [335764]
    Other proteins in same PDB: d5pana_
    automated match to d1klih_
    complexed with 7z4, ca, cl, gol, so4
69. Domain for 5pao:
  - Domain d5paoc_: 5pao C: [335699]
    Other proteins in same PDB: d5paoa_
    automated match to d1klih_
    complexed with 7z7, ca, cl, gol, so4
70. Domain for 5paq:
  - Domain d5paqb_: 5paq B: [335727]
    Other proteins in same PDB: d5paqa_
    automated match to d1klih_
    complexed with 7za, ca, cl, gol, so4
71. Domain for 5par:
  - Domain d5parc_: 5par C: [335754]
    Other proteins in same PDB: d5para_
    automated match to d1klih_
    complexed with ax7, ca, cl, gol, so4
72. Domain for 5pas:
  - Domain d5pasc_: 5pas C: [335820]
    Other proteins in same PDB: d5pasa_
    automated match to d1klih_
    complexed with 7zd, ca, cl, gol, so4
73. Domain for 5pat:
  - Domain d5patb_: 5pat B: [335749]
    Other proteins in same PDB: d5pata_
    automated match to d1klih_
    complexed with 7zg, so4
74. Domain for 5pau:
  - Domain d5pauc_: 5pau C: [335826]
    Other proteins in same PDB: d5paua_
    automated match to d1klih_
    complexed with 7zj, ca, cl, gol, so4
75. Domain for 5pav:
  - Domain d5pavc_: 5pav C: [335730]
    Other proteins in same PDB: d5pava_
    automated match to d1klih_
    complexed with 7zm, ca, cl, gol, so4
76. Domain for 5paw:
  - Domain d5pawb_: 5paw B: [335815]
    Other proteins in same PDB: d5pawa_
    automated match to d1klih_
    complexed with 7xm, ca, cl, so4
77. Domain for 5pax:
  - Domain d5paxc_: 5pax C: [335723]
    Other proteins in same PDB: d5paxa_
    automated match to d1klih_
    complexed with 7zp, ca, cl, gol, so4
78. Domain for 5pay:
  - Domain d5payc_: 5pay C: [335783]
    Other proteins in same PDB: d5paya_
    automated match to d1klih_
    complexed with 7zy, ca, cl, gol, so4
79. Domain for 5pb0:
  - Domain d5pb0b_: 5pb0 B: [335802]
    Other proteins in same PDB: d5pb0a_
    automated match to d1klih_
    complexed with 7lx, ca, cl, gol, so4
80. Domain for 5pb1:
  - Domain d5pb1d_: 5pb1 D: [335738]
    Other proteins in same PDB: d5pb1a_
    automated match to d1klih_
    complexed with bam, ca, gol, so4
81. Domain for 5pb2:
  - Domain d5pb2c_: 5pb2 C: [335810]
    Other proteins in same PDB: d5pb2a_
    automated match to d1klih_
    complexed with 9rp, ca, cl, gol, so4
82. Domain for 5pb3:
  - Domain d5pb3c_: 5pb3 C: [335785]
    Other proteins in same PDB: d5pb3a_
    automated match to d1klih_
    complexed with 9s1, ca, cl, gol, so4
83. Domain for 5pb4:
  - Domain d5pb4c_: 5pb4 C: [335809]
    Other proteins in same PDB: d5pb4a_
    automated match to d1klih_
    complexed with 9rs, ca, cl, gol, so4
84. Domain for 5pb5:
  - Domain d5pb5b_: 5pb5 B: [335788]
    Other proteins in same PDB: d5pb5a_
    automated match to d1klih_
    complexed with 9ry, ca, cl, gol, so4
85. Domain for 5pb6:
  - Domain d5pb6c_: 5pb6 C: [335800]
    Other proteins in same PDB: d5pb6a_
    automated match to d1klih_
    complexed with 9rv, ca, cl, gol, so4
86. Domain for 5tqe:
  - Domain d5tqeh_: 5tqe H: [329313]
    Other proteins in same PDB: d5tqel_
    automated match to d1klih_
    complexed with 7kq, ca, gol, so4
87. Domain for 5tqf:
  - Domain d5tqfh_: 5tqf H: [329344]
    Other proteins in same PDB: d5tqfl_
    automated match to d1klih_
    complexed with 7kr, ca, gol, so4
88. Domain for 5tqg:
  - Domain d5tqgh_: 5tqg H: [329317]
    Other proteins in same PDB: d5tqgl_
    automated match to d1klih_
    complexed with 7ks, ca, gol, so4
89. Domain for 5u6j:
  - Domain d5u6jh_: 5u6j H: [334275]
    Other proteins in same PDB: d5u6jl_
    automated match to d1klih_
    complexed with 82j, ca, gol, so4
90. Domain for 6r2w:
  - Domain d6r2wh_: 6r2w H: [378117]
    Other proteins in same PDB: d6r2wl1, d6r2wl2, d6r2wl3, d6r2wt1, d6r2wt2
    automated match to d4z6ah_
    complexed with 0z7, ca, fuc, tma

More info for Protein Coagulation factor VIIa from b.47.1.2: Eukaryotic proteases

Timeline for Protein Coagulation factor VIIa from b.47.1.2: Eukaryotic proteases:

Protein Coagulation factor VIIa from b.47.1.2: Eukaryotic proteases first appeared (with stable ids) in SCOP 1.55
Protein Coagulation factor VIIa from b.47.1.2: Eukaryotic proteases appears in SCOPe 2.07