SCOPe 2.08: Domain d2c4fh1: 2c4f H:16-257

Lineage for d2c4fh1 (2c4f H:16-257)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (90 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d2c4fh1: 2c4f H:16-257 [129805]
   Other proteins in same PDB: d2c4fl1, d2c4fl2, d2c4fl3, d2c4fu1
   automatically matched to d1cvwh_
   complexed with ca, fuc, gil, glc, nag

Details for d2c4fh1

PDB Entry: 2c4f, 1.72 Å

PDB Description: crystal structure of factor vii.stf complexed with pd0297121

PDB Compounds: (H:) coagulation factor vii precursor

SCOPe Domain Sequences for d2c4fh1:

Sequence; same for both SEQRES and ATOM records:

>d2c4fh1 b.47.1.2 (H:16-257) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Timeline for d2c4fh1:

• d2c4fh1 first appeared in SCOP 1.73
  
• d2c4fh1 appears in SCOPe 2.07