SCOPe 2.08: Domain d5l2yl_: 5l2y L:

Lineage for d5l2yl_ (5l2y L:)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.3: Knottins (small inhibitors, toxins, lectins) [57015] (19 superfamilies)
   disulfide-bound fold; contains beta-hairpin with two adjacent disulfides

4. Superfamily g.3.11: EGF/Laminin [57196] (8 families)

5. Family g.3.11.1: EGF-type module [57197] (23 proteins)

6. Protein Coagulation factor VIIa [57201] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57202] (97 PDB entries)
   Uniprot P08709 108-202 ! Uniprot P08709 107-202

8. Domain d5l2yl_: 5l2y L: [323451]
   Other proteins in same PDB: d5l2yh_
   automated match to d1cvwl_
   complexed with 70d, ca, gol, so4

Details for d5l2yl_

PDB Entry: 5l2y, 1.82 Å

PDB Description: factor viia in complex with the inhibitor 1-[(2r,15r)-2-[(1-amino-4- fluoroisoquinolin-6-yl)amino]-4,15,20-trimethyl-3,12-dioxo-13-oxa-4, 11-diazatricyclo[14.2.2.1~6,10~]henicosa-1(18),6,8,10(21),16,19- hexaen-7-yl] cyclobutane-1-carboxylic acid

PDB Compounds: (L:) Coagulation factor VII (light chain)

SCOPe Domain Sequences for d5l2yl_:

Sequence; same for both SEQRES and ATOM records:

>d5l2yl_ g.3.11.1 (L:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
icvnenggceqycsdhtgtkrscrchegyslladgvsctptveypcgkipilekr

Timeline for d5l2yl_:

• d5l2yl_ first appeared in SCOPe 2.06
  
• d5l2yl_ appears in SCOPe 2.07