SCOPe 2.08: Domain d2aeil3: 2aei L:1-48

Lineage for d2aeil3 (2aei L:1-48)

1. Root: SCOPe 2.08

2. Class g: Small proteins [56992] (100 folds)

3. Fold g.32: GLA-domain [57629] (1 superfamily)
   Calcium ion-bound

4. Superfamily g.32.1: GLA-domain [57630] (2 families)
   gamma-carboxy-glutamic acid-rich domain

5. Family g.32.1.1: GLA-domain [57631] (7 proteins)
   heterogeneous fold; applies to domains that adopt a different fold than the exemplar domain but has similar sequence and number of secondary structures
   

6. Protein Coagulation factor VIIa [57632] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [57633] (19 PDB entries)

8. Domain d2aeil3: 2aei L:1-48 [126634]
   Other proteins in same PDB: d2aeih_, d2aeil1, d2aeil2, d2aeit1, d2aeit2
   automated match to d1danl3
   complexed with 03r, ca, cac

Details for d2aeil3

PDB Entry: 2aei, 2.52 Å

PDB Description: Crystal structure of a ternary complex of factor VIIa/tissue factor and 2-[[6-[3-(aminoiminomethyl)phenoxy]-3,5-difluro-4-[(1-methyl-3-phenylpropyl)amino]-2-pyridinyl]oxy]-benzoic acid

PDB Compounds: (L:) Coagulation factor VII

SCOPe Domain Sequences for d2aeil3:

Sequence; same for both SEQRES and ATOM records:

>d2aeil3 g.32.1.1 (L:1-48) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
anafleelrpgslereckeeqcsfeeareifkdaertklfwisysdgd

Timeline for d2aeil3:

• d2aeil3 first appeared in SCOP 1.73
  
• d2aeil3 appears in SCOPe 2.07