Lineage for d4x8sh_ (4x8s H:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056099Protein Coagulation factor VIIa [50550] (1 species)
  7. 2056100Species Human (Homo sapiens) [TaxId:9606] [50551] (88 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 2056135Domain d4x8sh_: 4x8s H: [270831]
    Other proteins in same PDB: d4x8sl_
    automated match to d1klih_
    complexed with 3z7, ca, gol, so4

Details for d4x8sh_

PDB Entry: 4x8s (more details), 2.1 Å

PDB Description: factor viia in complex with the inhibitor 4-bromo-2-methoxyphenol
PDB Compounds: (H:) Factor VIIa (Heavy Chain)

SCOPe Domain Sequences for d4x8sh_:

Sequence, based on SEQRES records: (download)

>d4x8sh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records): (download)

>d4x8sh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrpniteymfcagysdgsk
dsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrseprp
gvllrapfp

SCOPe Domain Coordinates for d4x8sh_:

Click to download the PDB-style file with coordinates for d4x8sh_.
(The format of our PDB-style files is described here.)

Timeline for d4x8sh_: