SCOPe 2.08: Domain d1qfkh_: 1qfk H:

Lineage for d1qfkh_ (1qfk H:)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Coagulation factor VIIa [50550] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50551] (90 PDB entries)
   Uniprot P08709 213-466 ! Uniprot P08709 213-446

8. Domain d1qfkh_: 1qfk H: [26295]
   Other proteins in same PDB: d1qfkl1, d1qfkl2
   complexed with 0z6, ca, fuc, glc

Details for d1qfkh_

PDB Entry: 1qfk, 2.8 Å

PDB Description: structure of human factor viia and its implications for the triggering of blood coagulation

PDB Compounds: (H:) Coagulation factor VIIA heavy chain

SCOPe Domain Sequences for d1qfkh_:

Sequence, based on SEQRES records:

>d1qfkh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsrkvgdspniteymfcagy
sdgskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmr
seprpgvllrapfp

Sequence, based on observed residues (ATOM records):

>d1qfkh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}
ivggkvcpkgecpwqvlllvngaqlcggtlintiwvvsaahcfdkiknwrnliavlgehd
lsehdgdeqsrrvaqviipstyvpgttnhdiallrlhqpvvltdhvvplclpertfsert
lafvrfslvsgwgqlldrgatalelmvlnvprlmtqdclqqsvgdspniteymfcagysd
gskdsckgdsggphathyrgtwyltgivswgqgcatvghfgvytrvsqyiewlqklmrse
prpgvllrapfp

Timeline for d1qfkh_:

• d1qfkh_ first appeared (with stable ids) in SCOP 1.55
  
• d1qfkh_ appears in SCOPe 2.07