Lineage for d4zxxh_ (4zxx H:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2055629Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
    barrel, closed; n=6, S=8; greek-key
    duplication: consists of two domains of the same fold
  4. 2055630Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families) (S)
  5. 2055877Family b.47.1.2: Eukaryotic proteases [50514] (49 protein domains)
  6. 2056099Protein Coagulation factor VIIa [50550] (1 species)
  7. 2056100Species Human (Homo sapiens) [TaxId:9606] [50551] (88 PDB entries)
    Uniprot P08709 213-466 ! Uniprot P08709 213-446
  8. 2056149Domain d4zxxh_: 4zxx H: [275320]
    Other proteins in same PDB: d4zxxl_
    automated match to d1klih_
    complexed with 4t0, ca, so4

Details for d4zxxh_

PDB Entry: 4zxx (more details), 2.6 Å

PDB Description: factor viia in complex with the inhibitor n-{3-[(2r)-1-{(2r)-2-[(1- aminoisoquinolin-6-yl)amino]-2-phenylacetyl}pyrrolidin-2-yl]-4- (propan-2-ylsulfonyl)phenyl}acetamide
PDB Compounds: (H:) Coagulation factor VIIA heavy chain

SCOPe Domain Sequences for d4zxxh_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4zxxh_ b.47.1.2 (H:) Coagulation factor VIIa {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4zxxh_:

Click to download the PDB-style file with coordinates for d4zxxh_.
(The format of our PDB-style files is described here.)

Timeline for d4zxxh_: