Lineage for Protein: Cyclophilin (eukaryotic)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2064271Fold b.62: Cyclophilin-like [50890] (1 superfamily)
    barrel, closed; n=8, S=10; complex topology
  4. 2064272Superfamily b.62.1: Cyclophilin-like [50891] (5 families) (S)
  5. 2064273Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (13 protein domains)
    automatically mapped to Pfam PF00160
  6. 2064274Protein Cyclophilin (eukaryotic) [50893] (13 species)

Species:

  1. 2064275Aspergillus fumigatus [TaxId:5085] [141499] (1 PDB entry)
    Uniprot Q9Y7F6 8-178
  2. 2064277Baker's yeast (Saccharomyces cerevisiae), variant A [TaxId:4932] [101878] (1 PDB entry)
  3. 2064280Caenorhabditis elegans, isoform 3 [TaxId:6239] [50899] (3 PDB entries)
    1. Domain for 1dyw:
    2. Domain for 1e3b:
    3. Domain for 1e8k:
  4. 2064284Caenorhabditis elegans, isoform 5 [TaxId:6239] [82161] (1 PDB entry)
  5. 2064286Human (Homo sapiens), U4/U6 snRNP-specific cyclophilin snucyp-20 [TaxId:9606] [50896] (2 PDB entries)
    1. Domain for 1mzw:
      • 2064288Domain d1mzwa_: 1mzw A: [91503]
        complexed with a 30-residue peptide from U4/U6 snRNP 60kda protein, chain B
    2. Domain for 1qoi:
  6. 2064289Human (Homo sapiens), variant A [TaxId:9606] [50894] (113 PDB entries)
    Uniprot P05092
    1. Domains for 1ak4:
      1. 2064397Domain d1ak4a_: 1ak4 A: [27472]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
      2. 2064398Domain d1ak4b_: 1ak4 B: [27473]
        Other proteins in same PDB: d1ak4c_, d1ak4d_
    2. Domain for 1awq:
    3. Domains for 1awr:
      1. 2064388Domain d1awra_: 1awr A: [27464]
      2. 2064389Domain d1awrb_: 1awr B: [27465]
      3. 2064390Domain d1awrc_: 1awr C: [27466]
      4. 2064391Domain d1awrd_: 1awr D: [27467]
      5. 2064392Domain d1awre_: 1awr E: [27468]
      6. 2064393Domain d1awrf_: 1awr F: [27469]
    4. Domain for 1aws:
    5. Domains for 1awt:
      1. 2064400Domain d1awta_: 1awt A: [27481]
      2. 2064401Domain d1awtb_: 1awt B: [27482]
      3. 2064402Domain d1awtc_: 1awt C: [27483]
      4. 2064403Domain d1awtd_: 1awt D: [27484]
      5. 2064404Domain d1awte_: 1awt E: [27485]
      6. 2064405Domain d1awtf_: 1awt F: [27486]
    6. Domain for 1awu:
    7. Domains for 1awv:
      1. 2064410Domain d1awva_: 1awv A: [27475]
      2. 2064411Domain d1awvb_: 1awv B: [27476]
      3. 2064412Domain d1awvc_: 1awv C: [27477]
      4. 2064413Domain d1awvd_: 1awv D: [27478]
      5. 2064414Domain d1awve_: 1awv E: [27479]
      6. 2064415Domain d1awvf_: 1awv F: [27480]
    8. Domain for 1bck:
    9. Domain for 1cwa:
    10. Domain for 1cwb:
    11. Domain for 1cwc:
    12. Domain for 1cwf:
    13. Domain for 1cwh:
    14. Domain for 1cwi:
    15. Domain for 1cwj:
    16. Domain for 1cwk:
    17. Domain for 1cwl:
    18. Domain for 1cwm:
    19. Domain for 1cwo:
    20. Domain for 1fgl:
    21. Domains for 1m63:
      1. 2064407Domain d1m63c_: 1m63 C: [78679]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
        complexed with calcineurin and cyclosporin (chain D and H)
        complexed with ca, fe, zn
      2. 2064408Domain d1m63g_: 1m63 G: [78682]
        Other proteins in same PDB: d1m63a_, d1m63b_, d1m63e_, d1m63f_
        complexed with calcineurin and cyclosporin (chain D and H)
        complexed with ca, fe, zn
    22. Domains for 1m9c:
      1. 2064371Domain d1m9ca_: 1m9c A: [84886]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
      2. 2064372Domain d1m9cb_: 1m9c B: [84887]
        Other proteins in same PDB: d1m9cc_, d1m9cd_
    23. Domains for 1m9d:
      1. 2064335Domain d1m9da_: 1m9d A: [84890]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
      2. 2064336Domain d1m9db_: 1m9d B: [84891]
        Other proteins in same PDB: d1m9dc_, d1m9dd_
    24. Domains for 1m9e:
      1. 2064315Domain d1m9ea_: 1m9e A: [84894]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
      2. 2064316Domain d1m9eb_: 1m9e B: [84895]
        Other proteins in same PDB: d1m9ec_, d1m9ed_
    25. Domains for 1m9f:
      1. 2064306Domain d1m9fa_: 1m9f A: [84898]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
      2. 2064307Domain d1m9fb_: 1m9f B: [84899]
        Other proteins in same PDB: d1m9fc_, d1m9fd_
    26. Domains for 1m9x:
      1. 2064308Domain d1m9xa_: 1m9x A: [84905]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      2. 2064309Domain d1m9xb_: 1m9x B: [84906]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      3. 2064310Domain d1m9xe_: 1m9x E: [84909]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
      4. 2064311Domain d1m9xf_: 1m9x F: [84910]
        Other proteins in same PDB: d1m9xc_, d1m9xd_, d1m9xg_, d1m9xh_
    27. Domains for 1m9y:
      1. 2064330Domain d1m9ya_: 1m9y A: [84913]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      2. 2064331Domain d1m9yb_: 1m9y B: [84914]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      3. 2064332Domain d1m9ye_: 1m9y E: [84917]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
      4. 2064333Domain d1m9yf_: 1m9y F: [84918]
        Other proteins in same PDB: d1m9yc_, d1m9yd_, d1m9yg_, d1m9yh_
    28. Domain for 1mf8:
    29. Domain for 1mik:
    30. Domains for 1nmk:
      1. 2064342Domain d1nmka_: 1nmk A: [85875]
        complexed with sfm
      2. 2064343Domain d1nmkb_: 1nmk B: [85876]
        complexed with sfm
    31. Domain for 1oca:
    32. Domains for 1rmh:
      1. 2064394Domain d1rmha_: 1rmh A: [27470]
      2. 2064395Domain d1rmhb_: 1rmh B: [27471]
    33. Domain for 1vbs:
    34. Domains for 1vbt:
      1. 2064385Domain d1vbta_: 1vbt A: [27462]
      2. 2064386Domain d1vbtb_: 1vbt B: [27463]
    35. Domain for 1w8l:
    36. Domain for 1w8m:
    37. Domain for 1w8v:
    38. Domains for 1ynd:
      1. 2064299Domain d1ynda_: 1ynd A: [123721]
        automated match to d1ak4a_
        complexed with sfa
      2. 2064300Domain d1yndb_: 1ynd B: [123722]
        automated match to d1ak4a_
        complexed with sfa
    39. Domains for 1zkf:
      1. 2064383Domain d1zkfa_: 1zkf A: [125192]
        automated match to d1ak4a_
      2. 2064384Domain d1zkfb_: 1zkf B: [125193]
        automated match to d1ak4a_
    40. Domain for 2alf:
    41. Domain for 2cpl:
    42. Domain for 2cyh:
    43. Domain for 2ms4:
    44. Domain for 2mzu:
    45. Domain for 2n0t:
    46. Domains for 2rma:
      1. 2064348Domain d2rmaa_: 2rma A: [27435]
      2. 2064349Domain d2rmac_: 2rma C: [27436]
      3. 2064350Domain d2rmae_: 2rma E: [27437]
      4. 2064351Domain d2rmag_: 2rma G: [27438]
      5. 2064352Domain d2rmai_: 2rma I: [27439]
      6. 2064353Domain d2rmak_: 2rma K: [27440]
      7. 2064354Domain d2rmam_: 2rma M: [27441]
      8. 2064355Domain d2rmao_: 2rma O: [27442]
      9. 2064356Domain d2rmaq_: 2rma Q: [27443]
      10. 2064357Domain d2rmas_: 2rma S: [27444]
    47. Domains for 2rmb:
      1. 2064359Domain d2rmba_: 2rmb A: [27446]
      2. 2064360Domain d2rmbc_: 2rmb C: [27447]
      3. 2064361Domain d2rmbe_: 2rmb E: [27448]
      4. 2064362Domain d2rmbg_: 2rmb G: [27449]
      5. 2064363Domain d2rmbi_: 2rmb I: [27450]
      6. 2064364Domain d2rmbk_: 2rmb K: [27451]
      7. 2064365Domain d2rmbm_: 2rmb M: [27452]
      8. 2064366Domain d2rmbo_: 2rmb O: [27453]
      9. 2064367Domain d2rmbq_: 2rmb Q: [27454]
      10. 2064368Domain d2rmbs_: 2rmb S: [27455]
    48. Domains for 2x2a:
      1. 2064292Domain d2x2aa_: 2x2a A: [169818]
        automated match to d1ak4a_
        complexed with gol, so4
      2. 2064293Domain d2x2ab_: 2x2a B: [169819]
        automated match to d1ak4a_
        complexed with gol, so4
    49. Domains for 2x2d:
      1. 2064345Domain d2x2db_: 2x2d B: [169821]
        Other proteins in same PDB: d2x2dd_, d2x2de_
        automated match to d1ak4a_
      2. 2064346Domain d2x2dc_: 2x2d C: [169822]
        Other proteins in same PDB: d2x2dd_, d2x2de_
        automated match to d1ak4a_
    50. Domain for 3cyh:
    51. Domain for 3cys:
    52. Domain for 3k0m:
    53. Domain for 3k0n:
    54. Domain for 3k0o:
    55. Domain for 3k0p:
    56. Domain for 3k0q:
    57. Domain for 3k0r:
    58. Domain for 3rdd:
    59. Domain for 4cyh:
    60. Domain for 4ipz:
    61. Domain for 4n1m:
    62. Domain for 4n1n:
    63. Domain for 4n1o:
    64. Domain for 4n1p:
    65. Domain for 4n1q:
    66. Domain for 4n1r:
    67. Domain for 4n1s:
    68. Domain for 4yug:
    69. Domain for 4yuh:
    70. Domain for 4yui:
    71. Domain for 4yuj:
    72. Domain for 4yuk:
    73. Domain for 4yul:
    74. Domain for 4yum:
    75. Domain for 4yun:
    76. Domain for 4yuo:
    77. Domain for 4yup:
    78. Domain for 5cyh:
    79. Domain for 5f66:
    80. Domain for 5kul:
    81. Domain for 5kun:
    82. Domain for 5kuo:
    83. Domain for 5kuq:
    84. Domain for 5kur:
    85. Domain for 5kus:
    86. Domain for 5kuu:
    87. Domain for 5kuv:
    88. Domain for 5kuw:
    89. Domain for 5kuz:
    90. Domain for 5kv0:
    91. Domain for 5kv1:
    92. Domain for 5kv2:
    93. Domain for 5kv3:
    94. Domain for 5kv4:
    95. Domain for 5kv5:
    96. Domain for 5kv6:
    97. Domain for 5kv7:
    98. Domain for 5lud:
    99. Domain for 5noq:
    100. Domain for 5nor:
    101. Domain for 5nos:
    102. Domain for 5not:
    103. Domain for 5nou:
    104. Domain for 5nov:
    105. Domain for 5now:
    106. Domain for 5nox:
    107. Domain for 5noy:
    108. Domain for 5noz:
    109. Domains for 5t9u:
      1. 2285695Domain d5t9ub_: 5t9u B: [328996]
        automated match to d1m9ea_
        complexed with 7hg
      2. 2285701Domain d5t9ua_: 5t9u A: [329002]
        automated match to d1m9ea_
        complexed with 7hg
      3. 2285716Domain d5t9ud_: 5t9u D: [329017]
        automated match to d1m9ea_
        complexed with 7hg
      4. 2285723Domain d5t9uc_: 5t9u C: [329024]
        automated match to d1m9ea_
        complexed with 7hg
    110. Domain for 5t9w:
    111. Domain for 5t9z:
    112. Domain for 5ta2:
    113. Domain for 5ta4:
  7. 2064421Human (Homo sapiens), variant B [TaxId:9606] [50895] (1 PDB entry)
  8. 2064423Human (Homo sapiens), variant C [TaxId:9606] [141498] (1 PDB entry)
    Uniprot P45877 32-212
  9. 2064430Malaria parasite (Plasmodium falciparum) [TaxId:5833] [50900] (2 PDB entries)
    1. Domain for 1qng:
    2. Domains for 1qnh:
      1. 2064431Domain d1qnha_: 1qnh A: [27508]
        mutant
      2. 2064432Domain d1qnhb_: 1qnh B: [27509]
        mutant
  10. 2064434Mouse (Mus musculus), variant C [TaxId:10090] [50897] (1 PDB entry)
  11. 2064439Nematode (Brugia malayi) [TaxId:6279] [50898] (3 PDB entries)
    1. Domain for 1a33:
    2. Domain for 1a58:
    3. Domains for 1c5f:
      1. 2064442Domain d1c5fa_: 1c5f A: [27497]
      2. 2064443Domain d1c5fc_: 1c5f C: [27498]
      3. 2064444Domain d1c5fe_: 1c5f E: [27499]
      4. 2064445Domain d1c5fg_: 1c5f G: [27500]
      5. 2064446Domain d1c5fi_: 1c5f I: [27501]
      6. 2064447Domain d1c5fk_: 1c5f K: [27502]
      7. 2064448Domain d1c5fm_: 1c5f M: [27503]
      8. 2064449Domain d1c5fo_: 1c5f O: [27504]
  12. 2064450Plasmodium yoelii [TaxId:5861] [141500] (1 PDB entry)
    Uniprot Q7RSH5 25-210
  13. 2064452Trypanosoma cruzi [TaxId:5693] [117269] (2 PDB entries)
    Uniprot Q4DPB9 30-194
    1. Domains for 1xo7:
      1. 2064453Domain d1xo7a_: 1xo7 A: [115694]
        Structural genomics target
      2. 2064454Domain d1xo7b_: 1xo7 B: [115695]
        Structural genomics target
      3. 2064455Domain d1xo7c_: 1xo7 C: [115696]
        Structural genomics target
      4. 2064456Domain d1xo7d_: 1xo7 D: [115697]
        Structural genomics target
    2. Domains for 1xq7:
      1. 2064457Domain d1xq7a_: 1xq7 A: [115831]
        Structural genomics target
      2. 2064458Domain d1xq7b_: 1xq7 B: [115832]
        Structural genomics target
      3. 2064459Domain d1xq7c_: 1xq7 C: [115833]
        Structural genomics target

More info for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase)

Timeline for Protein Cyclophilin (eukaryotic) from b.62.1.1: Cyclophilin (peptidylprolyl isomerase):