PDB entry 1ynd
View 1ynd on RCSB PDB site
Description: Structure of human cyclophilin A in complex with the novel immunosuppressant sanglifehrin A at 1.6A resolution
Class: isomerase
Keywords: beta sandwich, cyclophilin-ligand complex, cyclosporin, isomerase, rotamase
Deposited on
2005-01-24, released
2005-04-05
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.164
AEROSPACI score: 0.61
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Peptidyl-prolyl cis-trans isomerase A
Species: Homo sapiens [TaxId:9606]
Gene: PPIA, CYPA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1ynda_ - Chain 'B':
Compound: Peptidyl-prolyl cis-trans isomerase A
Species: Homo sapiens [TaxId:9606]
Gene: PPIA, CYPA
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1yndb_ - Heterogens: SFA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1yndA (A:)
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgqle
Sequence, based on observed residues (ATOM records): (download)
>1yndA (A:)
vnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgfm
cqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictaktew
ldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgqle
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1yndB (B:)
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgqle
Sequence, based on observed residues (ATOM records): (download)
>1yndB (B:)
vnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgfm
cqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictaktew
ldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgqle