SCOPe 2.08: Domain d6x4qa1: 6x4q A:1-164

Lineage for d6x4qa1 (6x4q A:1-164)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.62: Cyclophilin-like [50890] (1 superfamily)
   barrel, closed; n=8, S=10; complex topology

4. Superfamily b.62.1: Cyclophilin-like [50891] (5 families)

5. Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (13 proteins)
   automatically mapped to Pfam PF00160

6. Protein Cyclophilin (eukaryotic) [50893] (13 species)

7. Species Human (Homo sapiens), variant A [TaxId:9606] [50894] (136 PDB entries)
   Uniprot P05092

8. Domain d6x4qa1: 6x4q A:1-164 [388369]
   Other proteins in same PDB: d6x4qa2
   automated match to d3icha_
   complexed with uoj

Details for d6x4qa1

PDB Entry: 6x4q, 1.8 Å

PDB Description: human cyclophilin a bound to a series of acylcic and macrocyclic inhibitors: (2r,5s,11s,14s,18e)-14-cyclobutyl-2,11,17,17-tetramethyl- 15-oxa-3,9,12,26,29-pentaazatetracyclo[18.5.3.1~5,9~.0~23, 27~]nonacosa-1(25),18,20(28),21,23,26-hexaene-4,10,13,16-tetrone (compound 33)

PDB Compounds: (A:) Peptidyl-prolyl cis-trans isomerase A

SCOPe Domain Sequences for d6x4qa1:

Sequence; same for both SEQRES and ATOM records:

>d6x4qa1 b.62.1.1 (A:1-164) Cyclophilin (eukaryotic) {Human (Homo sapiens), variant A [TaxId: 9606]}
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgql

Timeline for d6x4qa1:

• d6x4qa1 first appeared in SCOPe 2.07