Lineage for d5t9ud_ (5t9u D:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2806645Fold b.62: Cyclophilin-like [50890] (1 superfamily)
    barrel, closed; n=8, S=10; complex topology
  4. 2806646Superfamily b.62.1: Cyclophilin-like [50891] (5 families) (S)
  5. 2806647Family b.62.1.1: Cyclophilin (peptidylprolyl isomerase) [50892] (13 proteins)
    automatically mapped to Pfam PF00160
  6. 2806648Protein Cyclophilin (eukaryotic) [50893] (13 species)
  7. 2806663Species Human (Homo sapiens), variant A [TaxId:9606] [50894] (136 PDB entries)
    Uniprot P05092
  8. 2806826Domain d5t9ud_: 5t9u D: [329017]
    automated match to d1m9ea_
    complexed with 7hg

Details for d5t9ud_

PDB Entry: 5t9u (more details), 2.3 Å

PDB Description: discovery of a potent cyclophilin inhibitor (compound 3) based on structural simplification of sanglifehrin a
PDB Compounds: (D:) Peptidyl-prolyl cis-trans isomerase A

SCOPe Domain Sequences for d5t9ud_:

Sequence; same for both SEQRES and ATOM records: (download)

>d5t9ud_ b.62.1.1 (D:) Cyclophilin (eukaryotic) {Human (Homo sapiens), variant A [TaxId: 9606]}
mvnptvffdiavdgeplgrvsfelfadkvpktaenfralstgekgfgykgscfhriipgf
mcqggdftrhngtggksiygekfedenfilkhtgpgilsmanagpntngsqffictakte
wldgkhvvfgkvkegmniveamerfgsrngktskkitiadcgql

SCOPe Domain Coordinates for d5t9ud_:

Click to download the PDB-style file with coordinates for d5t9ud_.
(The format of our PDB-style files is described here.)

Timeline for d5t9ud_: