Lineage for Protein: Proliferating cell nuclear antigen (PCNA)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2539893Fold d.131: DNA clamp [55978] (1 superfamily)
    contains two helices and two beta sheets
    duplication: fold has internal pseudo two-fold symmetry
  4. 2539894Superfamily d.131.1: DNA clamp [55979] (3 families) (S)
  5. 2540079Family d.131.1.2: DNA polymerase processivity factor [55983] (5 proteins)
    duplication: consists of two domains of this fold
  6. 2540101Protein Proliferating cell nuclear antigen (PCNA) [55989] (8 species)

Species:

  1. 2540102Archaeoglobus fulgidus [TaxId:2234] [103254] (3 PDB entries)
    1. Domains for 1rwz:
      1. 2540103Domain d1rwza1: 1rwz A:1-122 [98005]
      2. 2540104Domain d1rwza2: 1rwz A:123-244 [98006]
    2. Domains for 1rxm:
      1. 2540107Domain d1rxma1: 1rxm A:1-122 [98035]
        complexed with a FEN-1 peptide, chain B
      2. 2540108Domain d1rxma2: 1rxm A:123-245 [98036]
        complexed with a FEN-1 peptide, chain B
    3. Domains for 1rxz:
      1. 2540105Domain d1rxza1: 1rxz A:1-122 [98067]
        complexed with a FEN-1 peptide, chain B
        protein/DNA complex
      2. 2540106Domain d1rxza2: 1rxz A:123-245 [98068]
        complexed with a FEN-1 peptide, chain B
        protein/DNA complex
  2. 2540109Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [55990] (6 PDB entries)
    Uniprot P15873
    1. Domains for 1plq:
      1. 2540110Domain d1plqa1: 1plq A:1-126 [41388]
        CASP1
        complexed with hg
      2. 2540111Domain d1plqa2: 1plq A:127-258 [41389]
        CASP1
        complexed with hg
    2. Domains for 1plr:
      1. 2540114Domain d1plra1: 1plr A:1-126 [41390]
      2. 2540115Domain d1plra2: 1plr A:127-258 [41391]
    3. Domains for 1sxj:
      1. 2540116Domain d1sxjf1: 1sxj F:1-126 [106091]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
      2. 2540117Domain d1sxjf2: 1sxj F:127-256 [106092]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
      3. 2540118Domain d1sxjg1: 1sxj G:1-126 [106093]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
      4. 2540119Domain d1sxjg2: 1sxj G:127-255 [106094]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
      5. 2540120Domain d1sxjh1: 1sxj H:1-126 [106095]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
      6. 2540121Domain d1sxjh2: 1sxj H:127-254 [106096]
        Other proteins in same PDB: d1sxja1, d1sxja2, d1sxjb1, d1sxjb2, d1sxjc1, d1sxjc2, d1sxjd1, d1sxjd2, d1sxje1, d1sxje2, d1sxjf3, d1sxjg3, d1sxjh3
        complexed with adp, ags, mg
    4. Domains for 2od8:
      1. 2540122Domain d2od8a1: 2od8 A:1-126 [139024]
        automatically matched to d1plq_1
      2. 2540123Domain d2od8a2: 2od8 A:127-255 [139025]
        automatically matched to d1plq_2
    5. Domains for 3f1w:
      1. 2540112Domain d3f1wa1: 3f1w A:1-126 [232134]
        automated match to d1plqa1
        mutant
      2. 2540113Domain d3f1wa2: 3f1w A:127-254 [232135]
        automated match to d1plqa2
        mutant
    6. Domains for 3k4x:
      1. 2540124Domain d3k4xa1: 3k4x A:2-126 [247107]
        automated match to d1plqa1
        protein/DNA complex
      2. 2540125Domain d3k4xa2: 3k4x A:127-253 [247108]
        automated match to d1plqa2
        protein/DNA complex
      3. 2540126Domain d3k4xa3: 3k4x A:269-393 [247109]
        automated match to d1plqa1
        protein/DNA complex
      4. 2540127Domain d3k4xa4: 3k4x A:394-522 [247110]
        automated match to d1plqa2
        protein/DNA complex
      5. 2540128Domain d3k4xa5: 3k4x A:536-660 [247111]
        automated match to d1plqa1
        protein/DNA complex
      6. 2540129Domain d3k4xa6: 3k4x A:661-787 [247112]
        automated match to d1plqa2
        protein/DNA complex
  3. 2540130Baker's yeast (Saccharomyces cerevisiae) [TaxId:559292] [270905] (9 PDB entries)
    1. Domains for 4yhr:
      1. 2540135Domain d4yhra1: 4yhr A:1-126 [270906]
        automated match to d1plqa1
      2. 2540136Domain d4yhra2: 4yhr A:127-256 [270907]
        automated match to d1plqa2
    2. Domains for 5jne:
      1. 2540131Domain d5jned1: 5jne D:1-126 [321089]
        Other proteins in same PDB: d5jneb1, d5jneb2, d5jnec_, d5jnef_, d5jneg_
        automated match to d1plqa1
        complexed with 6ln, gol, zn
      2. 2540132Domain d5jned2: 5jne D:127-254 [321090]
        Other proteins in same PDB: d5jneb1, d5jneb2, d5jnec_, d5jnef_, d5jneg_
        automated match to d1plqa2
        complexed with 6ln, gol, zn
      3. 2540133Domain d5jneh1: 5jne H:1-126 [321085]
        Other proteins in same PDB: d5jneb1, d5jneb2, d5jnec_, d5jnef_, d5jneg_
        automated match to d1plqa1
        complexed with 6ln, gol, zn
      4. 2540134Domain d5jneh2: 5jne H:127-256 [321086]
        Other proteins in same PDB: d5jneb1, d5jneb2, d5jnec_, d5jnef_, d5jneg_
        automated match to d1plqa2
        complexed with 6ln, gol, zn
    3. Domains for 5v7k:
      1. 3047805Domain d5v7ka1: 5v7k A:1-126 [347867]
        automated match to d1plqa1
        mutant
      2. 3047806Domain d5v7ka2: 5v7k A:127-255 [347868]
        automated match to d1plqa2
        mutant
    4. Domains for 5v7m:
      1. 3047789Domain d5v7ma1: 5v7m A:1-126 [347851]
        Other proteins in same PDB: d5v7ma3
        automated match to d1plqa1
        complexed with mg; mutant
      2. 3047790Domain d5v7ma2: 5v7m A:127-254 [347852]
        Other proteins in same PDB: d5v7ma3
        automated match to d1plqa2
        complexed with mg; mutant
    5. Domains for 5zut:
      1. 3053024Domain d5zuta1: 5zut A:1-126 [353086]
        automated match to d1plqa1
      2. 3053025Domain d5zuta2: 5zut A:127-255 [353087]
        automated match to d1plqa2
    6. Domains for 6cx2:
      1. 3050927Domain d6cx2a1: 6cx2 A:1-126 [350989]
        automated match to d1plqa1
        mutant
      2. 3050928Domain d6cx2a2: 6cx2 A:127-254 [350990]
        automated match to d1plqa2
        mutant
    7. Domains for 6cx3:
      1. 3050881Domain d6cx3a1: 6cx3 A:1-126 [350943]
        automated match to d1plqa1
        mutant
      2. 3050882Domain d6cx3a2: 6cx3 A:127-255 [350944]
        automated match to d1plqa2
        mutant
    8. Domains for 6cx4:
      1. 3050756Domain d6cx4a1: 6cx4 A:1-126 [350816]
        Other proteins in same PDB: d6cx4a3
        automated match to d1plqa1
        mutant
      2. 3050761Domain d6cx4a2: 6cx4 A:127-254 [350823]
        Other proteins in same PDB: d6cx4a3
        automated match to d1plqa2
        mutant
    9. Domains for 6e49:
      1. 3056319Domain d6e49b1: 6e49 B:1-126 [356381]
        automated match to d1plqa1
        protein/DNA complex
      2. 3056320Domain d6e49b2: 6e49 B:127-255 [356382]
        automated match to d1plqa2
        protein/DNA complex
      3. 3056324Domain d6e49c1: 6e49 C:1-126 [356386]
        automated match to d1plqa1
        protein/DNA complex
      4. 3056325Domain d6e49c2: 6e49 C:127-254 [356387]
        automated match to d1plqa2
        protein/DNA complex
      5. 3056600Domain d6e49a1: 6e49 A:1-126 [356662]
        automated match to d1plqa1
        protein/DNA complex
      6. 3056601Domain d6e49a2: 6e49 A:127-255 [356663]
        automated match to d1plqa2
        protein/DNA complex
  4. 2540137Haloferax volcanii [TaxId:2246] [225733] (1 PDB entry)
  5. 2540144Human (Homo sapiens) [TaxId:9606] [55991] (9 PDB entries)
    Uniprot P12004
    1. Domains for 1axc:
      1. 2540155Domain d1axca1: 1axc A:1-126 [41392]
        protein/DNA complex
      2. 2540156Domain d1axca2: 1axc A:127-255 [41393]
        protein/DNA complex
      3. 2540157Domain d1axcc1: 1axc C:1-126 [41394]
        protein/DNA complex
      4. 2540158Domain d1axcc2: 1axc C:127-255 [41395]
        protein/DNA complex
      5. 2540159Domain d1axce1: 1axc E:1-126 [41396]
        protein/DNA complex
      6. 2540160Domain d1axce2: 1axc E:127-255 [41397]
        protein/DNA complex
    2. Domains for 1u76:
      1. 2540173Domain d1u76a1: 1u76 A:1-126 [113077]
        complexed with a target peptide
      2. 2540174Domain d1u76a2: 1u76 A:127-255 [113078]
        complexed with a target peptide
      3. 2540175Domain d1u76c1: 1u76 C:1-126 [113079]
        complexed with a target peptide
      4. 2540176Domain d1u76c2: 1u76 C:127-255 [113080]
        complexed with a target peptide
      5. 2540177Domain d1u76e1: 1u76 E:1-126 [113081]
        complexed with a target peptide
      6. 2540178Domain d1u76e2: 1u76 E:127-255 [113082]
        complexed with a target peptide
    3. Domains for 1u7b:
      1. 2540145Domain d1u7ba1: 1u7b A:1-126 [113083]
        complexed with a target peptide
      2. 2540146Domain d1u7ba2: 1u7b A:127-255 [113084]
        complexed with a target peptide
    4. Domains for 1ul1:
      1. 2540185Domain d1ul1a1: 1ul1 A:1-126 [119684]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba1
        protein/DNA complex; complexed with mg
      2. 2540186Domain d1ul1a2: 1ul1 A:127-259 [119685]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba2
        protein/DNA complex; complexed with mg
      3. 2540187Domain d1ul1b1: 1ul1 B:1-126 [119686]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba1
        protein/DNA complex; complexed with mg
      4. 2540188Domain d1ul1b2: 1ul1 B:127-258 [119687]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba2
        protein/DNA complex; complexed with mg
      5. 2540189Domain d1ul1c1: 1ul1 C:1-126 [119688]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba1
        protein/DNA complex; complexed with mg
      6. 2540190Domain d1ul1c2: 1ul1 C:127-255 [119689]
        Other proteins in same PDB: d1ul1x1, d1ul1x2, d1ul1y1, d1ul1y2, d1ul1z1, d1ul1z2
        automated match to d1u7ba2
        protein/DNA complex; complexed with mg
    5. Domains for 1vyj:
      1. 2540161Domain d1vyja1: 1vyj A:1-126 [120530]
        automated match to d1u7ba1
        protein/DNA complex
      2. 2540162Domain d1vyja2: 1vyj A:127-257 [120531]
        automated match to d1u7ba2
        protein/DNA complex
      3. 2540163Domain d1vyjc1: 1vyj C:1-126 [120532]
        automated match to d1u7ba1
        protein/DNA complex
      4. 2540164Domain d1vyjc2: 1vyj C:127-257 [120533]
        automated match to d1u7ba2
        protein/DNA complex
      5. 2540165Domain d1vyje1: 1vyj E:1-126 [120534]
        automated match to d1u7ba1
        protein/DNA complex
      6. 2540166Domain d1vyje2: 1vyj E:127-257 [120535]
        automated match to d1u7ba2
        protein/DNA complex
      7. 2540167Domain d1vyjg1: 1vyj G:1-126 [120536]
        automated match to d1u7ba1
        protein/DNA complex
      8. 2540168Domain d1vyjg2: 1vyj G:127-260 [120537]
        automated match to d1u7ba2
        protein/DNA complex
      9. 2540169Domain d1vyji1: 1vyj I:1-126 [120538]
        automated match to d1u7ba1
        protein/DNA complex
      10. 2540170Domain d1vyji2: 1vyj I:127-257 [120539]
        automated match to d1u7ba2
        protein/DNA complex
      11. 2540171Domain d1vyjk1: 1vyj K:1-126 [120540]
        automated match to d1u7ba1
        protein/DNA complex
      12. 2540172Domain d1vyjk2: 1vyj K:127-257 [120541]
        automated match to d1u7ba2
        protein/DNA complex
    6. Domains for 1vym:
      1. 2540149Domain d1vyma1: 1vym A:1-126 [120542]
        automated match to d1u7ba1
      2. 2540150Domain d1vyma2: 1vym A:127-256 [120543]
        automated match to d1u7ba2
      3. 2540151Domain d1vymb1: 1vym B:1-126 [120544]
        automated match to d1u7ba1
      4. 2540152Domain d1vymb2: 1vym B:127-256 [120545]
        automated match to d1u7ba2
      5. 2540153Domain d1vymc1: 1vym C:1-126 [120546]
        automated match to d1u7ba1
      6. 2540154Domain d1vymc2: 1vym C:127-256 [120547]
        automated match to d1u7ba2
    7. Domains for 3tbl:
      1. 2540179Domain d3tbla1: 3tbl A:1-126 [216722]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba1
      2. 2540180Domain d3tbla2: 3tbl A:127-256 [216723]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba2
      3. 2540181Domain d3tblb1: 3tbl B:1-126 [216724]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba1
      4. 2540182Domain d3tblb2: 3tbl B:127-256 [216725]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba2
      5. 2540183Domain d3tblc1: 3tbl C:1-126 [216726]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba1
      6. 2540184Domain d3tblc2: 3tbl C:127-258 [216727]
        Other proteins in same PDB: d3tbld_, d3tble_
        automated match to d1u7ba2
    8. Domains for 3vkx:
      1. 2540147Domain d3vkxa1: 3vkx A:1-126 [217905]
        automated match to d1u7ba1
        complexed with cl, so4, t3
      2. 2540148Domain d3vkxa2: 3vkx A:127-255 [217906]
        automated match to d1u7ba2
        complexed with cl, so4, t3
    9. Domains for 3wgw:
      1. 2540191Domain d3wgwa1: 3wgw A:1-126 [236661]
        automated match to d1u7ba1
        protein/DNA complex; complexed with so4, t2b
      2. 2540192Domain d3wgwa2: 3wgw A:127-255 [236662]
        automated match to d1u7ba2
        protein/DNA complex; complexed with so4, t2b
      3. 2540193Domain d3wgwb1: 3wgw B:1-126 [236659]
        automated match to d1u7ba1
        protein/DNA complex; complexed with so4, t2b
      4. 2540194Domain d3wgwb2: 3wgw B:127-255 [236660]
        automated match to d1u7ba2
        protein/DNA complex; complexed with so4, t2b
  6. 2540195Pyrococcus furiosus [TaxId:186497] [316219] (1 PDB entry)
  7. 2540198Pyrococcus furiosus [TaxId:2261] [55992] (5 PDB entries)
    1. Domains for 1ge8:
      1. 2540203Domain d1ge8a1: 1ge8 A:2-117 [41398]
      2. 2540204Domain d1ge8a2: 1ge8 A:126-247 [41399]
    2. Domains for 1isq:
      1. 2540205Domain d1isqa1: 1isq A:2-119 [76779]
        protein/DNA complex
      2. 2540206Domain d1isqa2: 1isq A:126-247 [76780]
        protein/DNA complex
    3. Domains for 1iz4:
      1. 2540207Domain d1iz4a1: 1iz4 A:2-120 [83832]
        mutant
      2. 2540208Domain d1iz4a2: 1iz4 A:126-247 [83833]
        mutant
    4. Domains for 1iz5:
      1. 2540199Domain d1iz5a1: 1iz5 A:2-120 [83834]
        mutant
      2. 2540200Domain d1iz5a2: 1iz5 A:126-246 [83835]
        mutant
      3. 2540201Domain d1iz5b1: 1iz5 B:2-120 [83836]
        mutant
      4. 2540202Domain d1iz5b2: 1iz5 B:126-246 [83837]
        mutant
    5. Domains for 3a2f:
      1. 2540209Domain d3a2fb1: 3a2f B:2-117 [208098]
        Other proteins in same PDB: d3a2fa1, d3a2fa2
        automated match to d1ge8a1
        protein/DNA complex; mutant
      2. 2540210Domain d3a2fb2: 3a2f B:118-248 [208099]
        Other proteins in same PDB: d3a2fa1, d3a2fa2
        automated match to d1ge8a2
        protein/DNA complex; mutant
  8. 2540211Sulfolobus tokodaii [TaxId:111955] [111175] (1 PDB entry)
    Uniprot Q975N2

More info for Protein Proliferating cell nuclear antigen (PCNA) from d.131.1.2: DNA polymerase processivity factor

Timeline for Protein Proliferating cell nuclear antigen (PCNA) from d.131.1.2: DNA polymerase processivity factor: