SCOPe 2.08: Domain d3wgwa2: 3wgw A:127-255

Lineage for d3wgwa2 (3wgw A:127-255)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.131: DNA clamp [55978] (1 superfamily)
   contains two helices and two beta sheets
   duplication: fold has internal pseudo two-fold symmetry

4. Superfamily d.131.1: DNA clamp [55979] (3 families)

5. Family d.131.1.2: DNA polymerase processivity factor [55983] (5 proteins)
   duplication: consists of two domains of this fold

6. Protein Proliferating cell nuclear antigen (PCNA) [55989] (8 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55991] (10 PDB entries)
   Uniprot P12004

8. Domain d3wgwa2: 3wgw A:127-255 [236662]
   automated match to d1u7ba2
   protein/DNA complex; complexed with so4, t2b

Details for d3wgwa2

PDB Entry: 3wgw, 2.8 Å

PDB Description: structure of pcna bound to a small molecule inhibitor

PDB Compounds: (A:) Proliferating Cell Nuclear Antigen

SCOPe Domain Sequences for d3wgwa2:

Sequence, based on SEQRES records:

>d3wgwa2 d.131.1.2 (A:127-255) Proliferating cell nuclear antigen (PCNA) {Human (Homo sapiens) [TaxId: 9606]}
gipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgngniklsqts
nvdkeeeavtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvveykiadmgh
lkyylapki

Sequence, based on observed residues (ATOM records):

>d3wgwa2 d.131.1.2 (A:127-255) Proliferating cell nuclear antigen (PCNA) {Human (Homo sapiens) [TaxId: 9606]}
gipeqeyscvvkmpsgefaricrdlshigdavviscakdgvkfsasgelgngniklsqte
avtiemnepvqltfalrylnfftkatplsstvtlsmsadvplvveykiadmghlkyylap
ki

Timeline for d3wgwa2:

• d3wgwa2 first appeared in SCOPe 2.03
  
• d3wgwa2 appears in SCOPe 2.07