Lineage for Species: Human (Homo sapiens) [TaxId: 9606]

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2983145Protein Tyrosine-protein kinase SYK [118131] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 2983146Species Human (Homo sapiens) [TaxId:9606] [118132] (73 PDB entries)
    Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)

PDB entries in Species: Human (Homo sapiens) [TaxId: 9606]:

  1. Domain(s) for 1xba:
  2. Domain(s) for 1xbb:
  3. Domain(s) for 1xbc:
  4. Domain(s) for 3emg:
  5. Domain(s) for 3fqe:
  6. Domain(s) for 3fqh:
    1. 2983210Domain d3fqha_: 3fqh A: [175977]
      automated match to d1xbba_
      complexed with 057
    2. 2983211Domain d3fqhb_: 3fqh B: [175978]
      automated match to d1xbba_
      complexed with 057
  7. Domain(s) for 3fqs:
  8. Domain(s) for 3srv:
    1. 2983157Domain d3srva_: 3srv A: [185500]
      automated match to d1xbaa_
      complexed with gol, s19
    2. 2983158Domain d3srvb_: 3srv B: [185501]
      automated match to d1xbaa_
      complexed with gol, s19
  9. Domain(s) for 3tub:
  10. Domain(s) for 3tuc:
  11. Domain(s) for 3tud:
  12. Domain(s) for 3vf8:
  13. Domain(s) for 3vf9:
  14. Domain(s) for 4dfl:
  15. Domain(s) for 4dfn:
  16. Domain(s) for 4f4p:
  17. Domain(s) for 4fl1:
  18. Domain(s) for 4fyn:
  19. Domain(s) for 4fyo:
  20. Domain(s) for 4fz6:
  21. Domain(s) for 4fz7:
  22. Domain(s) for 4gfg:
  23. Domain(s) for 4i0r:
  24. Domain(s) for 4i0s:
  25. Domain(s) for 4i0t:
  26. Domain(s) for 4puz:
    1. 2983196Domain d4puza_: 4puz A: [257562]
      automated match to d1xbba_
      complexed with cg9
    2. 2983197Domain d4puzb_: 4puz B: [257563]
      automated match to d1xbba_
      complexed with cg9
  27. Domain(s) for 4pv0:
  28. Domain(s) for 4rss:
  29. Domain(s) for 4rx7:
  30. Domain(s) for 4rx8:
  31. Domain(s) for 4rx9:
  32. Domain(s) for 4wnm:
  33. Domain(s) for 4xg2:
  34. Domain(s) for 4xg3:
    1. 2983213Domain d4xg3a_: 4xg3 A: [280185]
      automated match to d3tuca_
      complexed with x3g
    2. 2983214Domain d4xg3b_: 4xg3 B: [280189]
      automated match to d3tuca_
      complexed with x3g
  35. Domain(s) for 4xg4:
  36. Domain(s) for 4xg6:
  37. Domain(s) for 4xg7:
  38. Domain(s) for 4xg8:
    1. 2983220Domain d4xg8a_: 4xg8 A: [280183]
      automated match to d3tuca_
      complexed with x8g
    2. 2983221Domain d4xg8c_: 4xg8 C: [280187]
      automated match to d3tuca_
      complexed with x8g
  39. Domain(s) for 4xg9:
    1. 2983227Domain d4xg9a_: 4xg9 A: [280191]
      automated match to d3tuca_
      complexed with x9g
    2. 2983228Domain d4xg9b_: 4xg9 B: [280184]
      automated match to d3tuca_
      complexed with x9g
  40. Domain(s) for 4yjo:
  41. Domain(s) for 4yjp:
  42. Domain(s) for 4yjq:
  43. Domain(s) for 4yjr:
  44. Domain(s) for 4yjs:
  45. Domain(s) for 4yjt:
  46. Domain(s) for 4yju:
  47. Domain(s) for 4yjv:
  48. Domain(s) for 5c26:
  49. Domain(s) for 5c27:
  50. Domain(s) for 5cxh:
  51. Domain(s) for 5cxz:
  52. Domain(s) for 5cy3:
  53. Domain(s) for 5ghv:
    1. 2983225Domain d5ghva_: 5ghv A: [319342]
      automated match to d3tuca_
      complexed with x5g
    2. 2983226Domain d5ghvb_: 5ghv B: [319441]
      automated match to d3tuca_
      complexed with x5g
  54. Domain(s) for 5lma:
  55. Domain(s) for 5lmb:
    1. 2983188Domain d5lmba_: 5lmb A: [322857]
      automated match to d3tuca_
      complexed with 6zf, gol
    2. 2983189Domain d5lmbb_: 5lmb B: [322835]
      automated match to d3tuca_
      complexed with 6zf, gol
  56. Domain(s) for 5t68:
    1. 2983229Domain d5t68a1: 5t68 A:363-635 [324581]
      Other proteins in same PDB: d5t68a2
      automated match to d3tuca_
      complexed with 77v
    2. 2983230Domain d5t68b_: 5t68 B: [324571]
      Other proteins in same PDB: d5t68a2
      automated match to d3tuca_
      complexed with 77v
  57. Domain(s) for 5tiu:
  58. Domain(s) for 5tr6:
  59. Domain(s) for 5tt7:
  60. Domain(s) for 5y5t:
  61. Domain(s) for 5y5u:
    1. 2983205Domain d5y5ua_: 5y5u A: [354128]
      automated match to d3tuca_
      complexed with 8ou
    2. 2983206Domain d5y5ub_: 5y5u B: [354111]
      automated match to d3tuca_
      complexed with 8ou
  62. Domain(s) for 6hm6:
  63. Domain(s) for 6hm7:
  64. Domain(s) for 6ssb:
  65. Domain(s) for 6vov:
    1. 2983190Domain d6vova_: 6vov A: [382206]
      automated match to d3fqha_
      complexed with r6d
    2. 2983191Domain d6vovb_: 6vov B: [382224]
      automated match to d3fqha_
      complexed with r6d
  66. Domain(s) for 6zc0:
  67. Domain(s) for 6zcp:
  68. Domain(s) for 6zcq:
  69. Domain(s) for 6zcr:
  70. Domain(s) for 6zcs:
  71. Domain(s) for 6zcu:
  72. Domain(s) for 6zcx:
  73. Domain(s) for 6zcy:

More info for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK

Timeline for Species Human (Homo sapiens) [TaxId:9606] from d.144.1.7 Tyrosine-protein kinase SYK: