Lineage for d1xbca1 (1xbc A:363-635)

  1. Root: SCOPe 2.08
  2. 2923792Class d: Alpha and beta proteins (a+b) [53931] (396 folds)
  3. 2979545Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2979546Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2979693Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2983145Protein Tyrosine-protein kinase SYK [118131] (1 species)
    PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase
  7. 2983146Species Human (Homo sapiens) [TaxId:9606] [118132] (73 PDB entries)
    Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576)
  8. 2983179Domain d1xbca1: 1xbc A:363-635 [115078]
    Other proteins in same PDB: d1xbca2
    Structural genomics target
    complexed with stu

Details for d1xbca1

PDB Entry: 1xbc (more details), 2 Å

PDB Description: crystal structure of the syk tyrosine kinase domain with staurosporin
PDB Compounds: (A:) Tyrosine-protein kinase SYK

SCOPe Domain Sequences for d1xbca1:

Sequence, based on SEQRES records: (download)

>d1xbca1 d.144.1.7 (A:363-635) Tyrosine-protein kinase SYK {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d1xbca1 d.144.1.7 (A:363-635) Tyrosine-protein kinase SYK {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1xbca1:

Click to download the PDB-style file with coordinates for d1xbca1.
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Timeline for d1xbca1:

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