Class d: Alpha and beta proteins (a+b) [53931] (396 folds) |
Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily) consists of two alpha+beta domains, C-terminal domain is mostly alpha helical |
Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) shares functional and structural similarities with the ATP-grasp fold and PIPK |
Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins) members organized in the groups and subfamiles specified by the comments |
Protein Tyrosine-protein kinase SYK [118131] (1 species) PTK group; SYK/ZAP-70 subfamily; non-membrane spanning protein tyrosine kinase |
Human (Homo sapiens) [TaxId:9606] [118132] (73 PDB entries) Uniprot P43405 363-635 # structure of the SH2 domain tandem region (9-265) is also known (55576) |
Domain d1xbaa1: 1xba A:363-635 [115076] Other proteins in same PDB: d1xbaa2 Structural genomics target |
Domain d1xbba1: 1xbb A:363-637 [115077] Other proteins in same PDB: d1xbba2 Structural genomics target complexed with sti |
Domain d1xbca1: 1xbc A:363-635 [115078] Other proteins in same PDB: d1xbca2 Structural genomics target complexed with stu |
Domain d3emga_: 3emg A: [175086] automated match to d1xbaa_ complexed with 685 |
Domain d3fqea1: 3fqe A:363-635 [175975] Other proteins in same PDB: d3fqea2 automated match to d1xbba_ complexed with p5c |
Domain d3fqha_: 3fqh A: [175977] automated match to d1xbba_ complexed with 057 |
Domain d3fqhb_: 3fqh B: [175978] automated match to d1xbba_ complexed with 057 |
Domain d3fqsa1: 3fqs A:363-635 [175985] Other proteins in same PDB: d3fqsa2 automated match to d1xbba_ complexed with 585 |
Domain d3srva_: 3srv A: [185500] automated match to d1xbaa_ complexed with gol, s19 |
Domain d3srvb_: 3srv B: [185501] automated match to d1xbaa_ complexed with gol, s19 |
Domain d3tuba_: 3tub A: [217031] automated match to d1u59a_ complexed with fpu |
Domain d3tuca_: 3tuc A: [217032] automated match to d1u59a_ complexed with fpw |
Domain d3tuda1: 3tud A:363-635 [217033] Other proteins in same PDB: d3tuda2 automated match to d1u59a_ complexed with fpx |
Domain d3vf8a_: 3vf8 A: [217795] automated match to d1u59a_ complexed with 0je |
Domain d3vf9a_: 3vf9 A: [217796] automated match to d1u59a_ complexed with 477 |
Domain d4dfla1: 4dfl A:363-635 [195550] Other proteins in same PDB: d4dfla2 automated match to d1xbaa_ complexed with 0k0, edo, so4 |
Domain d4dfna1: 4dfn A:363-635 [219739] Other proteins in same PDB: d4dfna2 automated match to d4dfla_ complexed with 0k1 |
Domain d4f4pa1: 4f4p A:365-635 [194235] Other proteins in same PDB: d4f4pa2 automated match to d1xbba_ complexed with 0sb, so4 |
Domain d4fl1a_: 4fl1 A: [221264] automated match to d1xbba_ complexed with anp, mg |
Domain d4fyna1: 4fyn A:363-635 [221596] Other proteins in same PDB: d4fyna2 automated match to d1xbba_ complexed with 0ve |
Domain d4fyoa1: 4fyo A:363-635 [193271] Other proteins in same PDB: d4fyoa2 automated match to d1xbba_ complexed with 0vf |
Domain d4fz6a1: 4fz6 A:363-635 [221629] Other proteins in same PDB: d4fz6a2 automated match to d1xbba_ complexed with 0vg |
Domain d4fz7a1: 4fz7 A:363-635 [221630] Other proteins in same PDB: d4fz7a2 automated match to d1xbba_ complexed with 0vh |
Domain d4gfga1: 4gfg A:363-635 [221885] Other proteins in same PDB: d4gfga2 automated match to d1xbba_ complexed with 0xf |
Domain d4i0ra1: 4i0r A:363-635 [228655] Other proteins in same PDB: d4i0ra2 automated match to d1xbba_ complexed with 1b4 |
Domain d4i0sa1: 4i0s A:363-635 [228656] Other proteins in same PDB: d4i0sa2 automated match to d1xbba_ complexed with 1b5 |
Domain d4i0ta1: 4i0t A:363-635 [228654] Other proteins in same PDB: d4i0ta2 automated match to d1xbba_ complexed with 1b6 |
Domain d4puza_: 4puz A: [257562] automated match to d1xbba_ complexed with cg9 |
Domain d4puzb_: 4puz B: [257563] automated match to d1xbba_ complexed with cg9 |
Domain d4pv0a1: 4pv0 A:363-635 [257561] Other proteins in same PDB: d4pv0a2 automated match to d4fyoa_ complexed with cg4, cl |
Domain d4rssa_: 4rss A: [278423] automated match to d3tuca_ complexed with 4mg |
Domain d4rx7a1: 4rx7 A:363-635 [270468] Other proteins in same PDB: d4rx7a2 automated match to d3tuca_ complexed with 3yv, fmt, gol |
Domain d4rx8a1: 4rx8 A:364-635 [270474] Other proteins in same PDB: d4rx8a2 automated match to d3tuca_ complexed with 3yx, gol |
Domain d4rx9a1: 4rx9 A:363-635 [270482] Other proteins in same PDB: d4rx9a2 automated match to d3tuca_ complexed with 3yt, gol |
Domain d4wnma1: 4wnm A:363-635 [311578] Other proteins in same PDB: d4wnma2 automated match to d3tuca_ complexed with 3rt, so4 |
Domain d4xg2a1: 4xg2 A:364-635 [280193] Other proteins in same PDB: d4xg2a2 automated match to d3tuca_ |
Domain d4xg3a_: 4xg3 A: [280185] automated match to d3tuca_ complexed with x3g |
Domain d4xg3b_: 4xg3 B: [280189] automated match to d3tuca_ complexed with x3g |
Domain d4xg4a_: 4xg4 A: [280182] automated match to d3tuca_ complexed with x4g |
Domain d4xg6a1: 4xg6 A:363-635 [280186] Other proteins in same PDB: d4xg6a2 automated match to d3tuca_ complexed with x6g |
Domain d4xg7a1: 4xg7 A:364-635 [280188] Other proteins in same PDB: d4xg7a2 automated match to d3tuca_ complexed with x7g |
Domain d4xg8a_: 4xg8 A: [280183] automated match to d3tuca_ complexed with x8g |
Domain d4xg8c_: 4xg8 C: [280187] automated match to d3tuca_ complexed with x8g |
Domain d4xg9a_: 4xg9 A: [280191] automated match to d3tuca_ complexed with x9g |
Domain d4xg9b_: 4xg9 B: [280184] automated match to d3tuca_ complexed with x9g |
Domain d4yjoa_: 4yjo A: [277696] automated match to d3tuca_ complexed with 4df, gol |
Domain d4yjpa_: 4yjp A: [277685] automated match to d3tuca_ complexed with 4dl, dms |
Domain d4yjqa_: 4yjq A: [277688] automated match to d3tuca_ complexed with 4dk |
Domain d4yjra_: 4yjr A: [277689] automated match to d3tuca_ complexed with 4dj |
Domain d4yjsa_: 4yjs A: [277687] automated match to d3tuca_ complexed with 4dn |
Domain d4yjta_: 4yjt A: [277684] automated match to d3tuca_ complexed with 4dq, gol |
Domain d4yjua_: 4yju A: [277686] automated match to d3tuca_ complexed with 4do |
Domain d4yjva_: 4yjv A: [278232] automated match to d3tuca_ complexed with 4dt |
Domain d5c26a1: 5c26 A:363-635 [277851] Other proteins in same PDB: d5c26a2 automated match to d3tuca_ complexed with 50h |
Domain d5c27a1: 5c27 A:363-635 [277850] Other proteins in same PDB: d5c27a2 automated match to d3tuca_ complexed with 50j, gol |
Domain d5cxha1: 5cxh A:363-635 [277113] Other proteins in same PDB: d5cxha2 automated match to d3tuca_ complexed with 55m |
Domain d5cxza1: 5cxz A:363-635 [276972] Other proteins in same PDB: d5cxza2 automated match to d3tuca_ complexed with 55u, cl, gol |
Domain d5cy3a1: 5cy3 A:360-635 [277181] Other proteins in same PDB: d5cy3a2 automated match to d3tuca_ complexed with 55y |
Domain d5ghva_: 5ghv A: [319342] automated match to d3tuca_ complexed with x5g |
Domain d5ghvb_: 5ghv B: [319441] automated match to d3tuca_ complexed with x5g |
Domain d5lmaa_: 5lma A: [322851] automated match to d3tuca_ complexed with 6zg, dms, gol |
Domain d5lmba_: 5lmb A: [322857] automated match to d3tuca_ complexed with 6zf, gol |
Domain d5lmbb_: 5lmb B: [322835] automated match to d3tuca_ complexed with 6zf, gol |
Domain d5t68a1: 5t68 A:363-635 [324581] Other proteins in same PDB: d5t68a2 automated match to d3tuca_ complexed with 77v |
Domain d5t68b_: 5t68 B: [324571] Other proteins in same PDB: d5t68a2 automated match to d3tuca_ complexed with 77v |
Domain d5tiua1: 5tiu A:363-635 [328195] Other proteins in same PDB: d5tiua2 automated match to d3tuca_ complexed with 7cu |
Domain d5tr6a1: 5tr6 A:362-635 [326837] Other proteins in same PDB: d5tr6a2 automated match to d3tuca_ complexed with 7kg, edo |
Domain d5tt7a1: 5tt7 A:358-635 [326791] Other proteins in same PDB: d5tt7a2 automated match to d3tuca_ complexed with 7kf |
Domain d5y5ta_: 5y5t A: [354154] automated match to d3tuca_ complexed with 8or |
Domain d5y5ua_: 5y5u A: [354128] automated match to d3tuca_ complexed with 8ou |
Domain d5y5ub_: 5y5u B: [354111] automated match to d3tuca_ complexed with 8ou |
Domain d6hm6a_: 6hm6 A: [358747] automated match to d3tuca_ complexed with gdk, gol |
Domain d6hm7a_: 6hm7 A: [358642] automated match to d3tuca_ complexed with br, dms, gdh, gol |
Domain d6ssba1: 6ssb A:363-635 [391728] Other proteins in same PDB: d6ssba2 automated match to d3tuca_ complexed with lue |
Domain d6vova_: 6vov A: [382206] automated match to d3fqha_ complexed with r6d |
Domain d6vovb_: 6vov B: [382224] automated match to d3fqha_ complexed with r6d |
Domain d6zc0a1: 6zc0 A:363-635 [407523] Other proteins in same PDB: d6zc0a2 automated match to d3tuca_ complexed with qdz |
Domain d6zcpa1: 6zcp A:363-635 [407499] Other proteins in same PDB: d6zcpa2 automated match to d3tuca_ complexed with qfk |
Domain d6zcqa1: 6zcq A:363-635 [407597] Other proteins in same PDB: d6zcqa2 automated match to d3tuca_ complexed with qfb |
Domain d6zcra1: 6zcr A:363-635 [407533] Other proteins in same PDB: d6zcra2 automated match to d3tuca_ complexed with 5jg |
Domain d6zcsa1: 6zcs A:363-635 [407473] Other proteins in same PDB: d6zcsa2 automated match to d3tuca_ complexed with qfe |
Domain d6zcua1: 6zcu A:363-635 [407554] Other proteins in same PDB: d6zcua2 automated match to d3tuca_ complexed with 5jg |
Domain d6zcxa1: 6zcx A:363-635 [407552] Other proteins in same PDB: d6zcxa2 automated match to d3tuca_ complexed with qfq |
Domain d6zcya1: 6zcy A:363-635 [407463] Other proteins in same PDB: d6zcya2 automated match to d3tuca_ complexed with qf8 |
Timeline for Protein Tyrosine-protein kinase SYK from d.144.1.7: Protein kinases, catalytic subunit: