PDB entry 6zcy

View 6zcy on RCSB PDB site
Description: SYK Kinase domain in complex with diamine inhibitor 16
Class: transferase
Keywords: SYK Kinase TRANSFERASE INHIBITOR, TRANSFERASE
Deposited on 2020-06-12, released 2021-06-23
The last revision prior to the SCOPe 2.08 freeze date was dated 2021-06-23, with a file datestamp of 2021-06-18.
Experiment type: XRAY
Resolution: 1.81 Å
R-factor: N/A
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tyrosine-protein kinase SYK
    Species: Homo sapiens [TaxId:9606]
    Gene: SYK
    Database cross-references and differences (RAF-indexed):
    • Uniprot P43405 (Start-292)
      • expression tag (293-294)
    Domains in SCOPe 2.08: d6zcya1, d6zcya2
  • Heterogens: QF8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6zcyA (A:)
mdtevyespyadpeeirpkevyldrklltledkelgsgnfgtvkkgyyqmkkvvktvavk
ilkneandpalkdellaeanvmqqldnpyivrmigiceaeswmlvmemaelgplnkylqq
nrhvkdkniielvhqvsmgmkyleesnfvhrdlaarnvllvtqhyakisdfglskalrad
enyykaqthgkwpvkwyapecinyykfssksdvwsfgvlmweafsygqkpyrgmkgsevt
amlekgermgcpagcpremydlmnlcwtydvenrpgfaavelrlrnyyydvvnhhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >6zcyA (A:)
vyldrklltledkelgsfgtvkkgyyqmkkvvktvavkilklkdellaeanvmqqldnpy
ivrmigiceaeswmlvmemaelgplnkylqqnrhvkdkniielvhqvsmgmkyleesnfv
hrdlaarnvllvtqhyakisdfglskalradenyykaqthkwpvkwyapecinyykfssk
sdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcpagcpremydlmnlcwtyd
venrpgfaavelrlrnyyydvvnhh