Lineage for Protein: Serine hydroxymethyltransferase

  1. Root: SCOPe 2.08
  2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
    main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest
  4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families) (S)
  5. Family c.67.1.4: GABA-aminotransferase-like [53417] (17 proteins)
    formerly omega-Aminoacid:pyruvate aminotransferase-like
  6. Protein Serine hydroxymethyltransferase [53429] (7 species)

Species:

  1. Bacillus stearothermophilus [TaxId:1422] [75272] (39 PDB entries)
    1. Domain for 1kkj:
    2. Domain for 1kkp:
    3. Domain for 1kl1:
    4. Domains for 1kl2:
      1. Domain d1kl2a_: 1kl2 A: [72664]
        complexed with fon, gly, plp
      2. Domain d1kl2b_: 1kl2 B: [72665]
        complexed with fon, gly, plp
    5. Domain for 1yjs:
    6. Domain for 1yjy:
    7. Domain for 1yjz:
    8. Domain for 2vgs:
    9. Domain for 2vgt:
    10. Domain for 2vgu:
    11. Domain for 2vgv:
    12. Domain for 2vgw:
    13. Domain for 2vi8:
    14. Domain for 2vi9:
    15. Domain for 2via:
    16. Domain for 2vib:
    17. Domain for 2vmn:
    18. Domain for 2vmo:
    19. Domain for 2vmp:
    20. Domain for 2vmq:
    21. Domain for 2vmr:
    22. Domain for 2vms:
    23. Domain for 2vmt:
    24. Domain for 2vmu:
    25. Domain for 2vmv:
    26. Domain for 2vmw:
    27. Domain for 2vmx:
    28. Domains for 2vmy:
      1. Domain d2vmya_: 2vmy A: [168725]
        automated match to d1kkja_
        complexed with ffo, gly, mrd, plp
      2. Domain d2vmyb_: 2vmy B: [168726]
        automated match to d1kkja_
        complexed with ffo, gly, mrd, plp
    29. Domain for 2vmz:
    30. Domain for 2w7d:
    31. Domain for 2w7e:
    32. Domain for 2w7f:
    33. Domain for 2w7g:
    34. Domain for 2w7h:
    35. Domain for 2w7i:
    36. Domain for 2w7j:
    37. Domain for 2w7k:
    38. Domain for 2w7l:
    39. Domain for 2w7m:
  2. Escherichia coli [TaxId:562] [53433] (2 PDB entries)
    1. Domains for 1dfo:
      1. Domain d1dfoa_: 1dfo A: [34480]
        complexed with ffo, plg
      2. Domain d1dfob_: 1dfo B: [34481]
        complexed with ffo, plg
      3. Domain d1dfoc_: 1dfo C: [34482]
        complexed with ffo, plg
      4. Domain d1dfod_: 1dfo D: [34483]
        complexed with ffo, plg
    2. Domains for 1eqb:
      1. Domain d1eqba_: 1eqb A: [34484]
        complexed with ffo, gly, plp; mutant
      2. Domain d1eqbb_: 1eqb B: [34485]
        complexed with ffo, gly, plp; mutant
      3. Domain d1eqbc_: 1eqb C: [34486]
        complexed with ffo, gly, plp; mutant
      4. Domain d1eqbd_: 1eqb D: [34487]
        complexed with ffo, gly, plp; mutant
  3. Soybean (Glycine max) [TaxId:3847] [380557] (5 PDB entries)
    1. Domains for 6uxh:
      1. Domain d6uxha1: 6uxh A:1-470 [380591]
        Other proteins in same PDB: d6uxha2, d6uxhb2
        automated match to d5v7ia_
        complexed with edo
      2. Domain d6uxhb1: 6uxh B:1-470 [380558]
        Other proteins in same PDB: d6uxha2, d6uxhb2
        automated match to d5v7ia_
        complexed with edo
    2. Domains for 6uxi:
      1. Domain d6uxia1: 6uxi A:1-470 [380562]
        Other proteins in same PDB: d6uxia2, d6uxib2
        automated match to d5v7ia_
        complexed with edo, plg
      2. Domain d6uxib1: 6uxi B:1-471 [380585]
        Other proteins in same PDB: d6uxia2, d6uxib2
        automated match to d5v7ia_
        complexed with edo, plg
    3. Domains for 6uxj:
      1. Domain d6uxja1: 6uxj A:1-470 [380595]
        Other proteins in same PDB: d6uxja2, d6uxjb2, d6uxjc2, d6uxjd2
        automated match to d5v7ia_
        complexed with edo, ffo, plg
      2. Domain d6uxjb1: 6uxj B:1-471 [380614]
        Other proteins in same PDB: d6uxja2, d6uxjb2, d6uxjc2, d6uxjd2
        automated match to d5v7ia_
        complexed with edo, ffo, plg
      3. Domain d6uxjc1: 6uxj C:1-470 [380619]
        Other proteins in same PDB: d6uxja2, d6uxjb2, d6uxjc2, d6uxjd2
        automated match to d5v7ia_
        complexed with edo, ffo, plg
      4. Domain d6uxjd1: 6uxj D:1-471 [380609]
        Other proteins in same PDB: d6uxja2, d6uxjb2, d6uxjc2, d6uxjd2
        automated match to d5v7ia_
        complexed with edo, ffo, plg
    4. Domains for 6uxk:
      1. Domain d6uxka1: 6uxk A:1-470 [380602]
        Other proteins in same PDB: d6uxka2, d6uxkb2
        automated match to d5v7ia_
        complexed with edo
      2. Domain d6uxkb1: 6uxk B:1-470 [380617]
        Other proteins in same PDB: d6uxka2, d6uxkb2
        automated match to d5v7ia_
        complexed with edo
    5. Domains for 6uxl:
      1. Domain d6uxla1: 6uxl A:1-470 [380600]
        Other proteins in same PDB: d6uxla2, d6uxlb2
        automated match to d5v7ia_
        complexed with plg
      2. Domain d6uxlb1: 6uxl B:1-470 [380578]
        Other proteins in same PDB: d6uxla2, d6uxlb2
        automated match to d5v7ia_
        complexed with plg
  4. Human (Homo sapiens) [TaxId:9606] [53432] (2 PDB entries)
    1. Domain for 1bj4:
    2. Domain for 6m5w:
  5. Human (Homo sapiens), mitochondrial [TaxId:9606] [142671] (8 PDB entries)
    Uniprot P34897 42-504
    1. Domain for 2a7v:
    2. Domains for 4pvf:
      1. Domain d4pvfa_: 4pvf A: [268595]
        automated match to d3ou5a_
        complexed with gol, peg
      2. Domain d4pvfb_: 4pvf B: [268596]
        automated match to d3ou5a_
        complexed with gol, peg
    3. Domains for 5v7i:
      1. Domain d5v7ia_: 5v7i A: [340128]
        automated match to d3ou5a_
        complexed with 8z1, gly, gol, peg
      2. Domain d5v7ib_: 5v7i B: [340115]
        automated match to d3ou5a_
        complexed with 8z1, gly, gol, peg
    4. Domains for 5x3v:
      1. Domain d5x3va_: 5x3v A: [348376]
        automated match to d3ou5a_
        complexed with so4; mutant
      2. Domain d5x3vb_: 5x3v B: [348315]
        automated match to d3ou5a_
        complexed with so4; mutant
    5. Domain for 6dk3:
    6. Domains for 6m5o:
      1. Domain d6m5oa_: 6m5o A: [399986]
        automated match to d3ou5a_
        complexed with dxc, gly
      2. Domain d6m5ob_: 6m5o B: [400001]
        automated match to d3ou5a_
        complexed with dxc, gly
    7. Domains for 6qvg:
      1. Domain d6qvga_: 6qvg A: [373763]
        automated match to d3ou5a_
        complexed with act, ddf, gly, gol, na, peg, plp
      2. Domain d6qvgb_: 6qvg B: [373759]
        automated match to d3ou5a_
        complexed with act, ddf, gly, gol, na, peg, plp
    8. Domains for 6qvl:
      1. Domain d6qvla_: 6qvl A: [373774]
        automated match to d3ou5a_
        complexed with 4dw, ca, gol, peg, plp
      2. Domain d6qvlb_: 6qvl B: [373772]
        automated match to d3ou5a_
        complexed with 4dw, ca, gol, peg, plp
  6. Mouse (Mus musculus) [TaxId:10090] [53431] (1 PDB entry)
  7. Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53430] (6 PDB entries)
    Uniprot P07511
    1. Domains for 1cj0:
      1. Domain d1cj0a_: 1cj0 A: [34473]
        complexed with plp
      2. Domain d1cj0b_: 1cj0 B: [34474]
        complexed with plp
    2. Domains for 1ls3:
      1. Domain d1ls3a_: 1ls3 A: [78172]
        complexed with gly, gol, plp, tgf
      2. Domain d1ls3b_: 1ls3 B: [78173]
        complexed with gly, gol, plp, tgf
      3. Domain d1ls3c_: 1ls3 C: [78174]
        complexed with gly, gol, plp, tgf
      4. Domain d1ls3d_: 1ls3 D: [78175]
        complexed with gly, gol, plp, tgf
    3. Domains for 1rv3:
      1. Domain d1rv3a_: 1rv3 A: [105101]
        complexed with gly, plp, po4; mutant
      2. Domain d1rv3b_: 1rv3 B: [105102]
        complexed with gly, plp, po4; mutant
    4. Domains for 1rv4:
      1. Domain d1rv4a_: 1rv4 A: [105103]
        complexed with plp, po4; mutant
      2. Domain d1rv4b_: 1rv4 B: [105104]
        complexed with plp, po4; mutant
    5. Domains for 1rvu:
      1. Domain d1rvua_: 1rvu A: [105106]
        complexed with plp, po4; mutant
      2. Domain d1rvub_: 1rvu B: [105107]
        complexed with plp, po4; mutant
    6. Domains for 1rvy:
      1. Domain d1rvya_: 1rvy A: [105108]
        complexed with plg, plp, po4; mutant
      2. Domain d1rvyb_: 1rvy B: [105109]
        complexed with plg, plp, po4; mutant

More info for Protein Serine hydroxymethyltransferase from c.67.1.4: GABA-aminotransferase-like

Timeline for Protein Serine hydroxymethyltransferase from c.67.1.4: GABA-aminotransferase-like: