SCOPe 2.08: Domain d8aqlb_: 8aql B:

Lineage for d8aqlb_ (8aql B:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.67: PLP-dependent transferase-like [53382] (3 superfamilies)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (10 families)

5. Family c.67.1.4: GABA-aminotransferase-like [53417] (17 proteins)
   formerly omega-Aminoacid:pyruvate aminotransferase-like

6. Protein Serine hydroxymethyltransferase [53429] (7 species)

7. Species Human (Homo sapiens), mitochondrial [TaxId:9606] [142671] (9 PDB entries)
   Uniprot P34897 42-504

8. Domain d8aqlb_: 8aql B: [423372]
   automated match to d6dk3a_
   complexed with edo, plg

Details for d8aqlb_

PDB Entry: 8aql, 1.23 Å

PDB Description: high-resolution crystal structure of human shmt2

PDB Compounds: (B:) Serine hydroxymethyltransferase, mitochondrial

SCOPe Domain Sequences for d8aqlb_:

Sequence, based on SEQRES records:

>d8aqlb_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
qtgeanrgwtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnn
kysegypgkryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytal
lqphdrimgldlpdgghlthgymsdvkrisatsiffesmpyklnpktglidynqlaltar
lfrprliiagtsayarlidyarmrevcdevkahlladmahisglvaakvipspfkhadiv
tttthktlrgarsglifyrkgvkavdpktgreipytfedrinfavfpslqggphnhaiaa
vavalkqactpmfreyslqvlknaramadallergyslvsggtdnhlvlvdlrpkgldga
raervlelvsitankntcpgdrsaitpgglrlgapaltsrqfreddfrrvvdfidegvni
glevksktaklqdfksfllkdsetsqrlanlrqrveqfarafpmpgfdeh

Sequence, based on observed residues (ATOM records):

>d8aqlb_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Human (Homo sapiens), mitochondrial [TaxId: 9606]}
qtgeanrgwtgqeslsdsdpemwellqrekdrqcrgleliasenfcsraalealgsclnn
kysegypgkryyggaevvdeiellcqrraleafdldpaqwgvnvqpysgspanlavytal
lqphdrimgldlpdgghlthgymsdvkrisatsiffesmpyklnpktglidynqlaltar
lfrprliiagtsayarlidyarmrevcdevkahlladmahisglvaakvipspfkhadiv
tttthktlrgarsglifyrkgvkipytfedrinfavfpslqggphnhaiaavavalkqac
tpmfreyslqvlknaramadallergyslvsggtdnhlvlvdlrpkgldgaraervlelv
sitankntcpgdrsaitpgglrlgapaltsrqfreddfrrvvdfidegvniglevkskta
klqdfksfllkdsetsqrlanlrqrveqfarafpmpgfdeh

Timeline for d8aqlb_:

• d8aqlb_ is new in SCOPe 2.08-stable