PDB entry 2vgu

View 2vgu on RCSB PDB site
Description: crystal structure of e53qbsshmt with l-serine
Class: transferase
Keywords: plp-dependent enzymes, shmt, e53q, transferase, enzyme memory, pyridoxal phosphate, one-carbon metabolism
Deposited on 2007-11-15, released 2007-12-04
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.168
AEROSPACI score: 0.53 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: serine hydroxymethyltransferase
    Species: BACILLUS STEAROTHERMOPHILUS [TaxId:1422]
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q7SIB6 (0-404)
      • engineered mutation (52)
    • PDB 2VGU (405-End)
    Domains in SCOPe 2.08: d2vgua_
  • Heterogens: SER, PLP, MPD, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >2vguA (A:)
mkylpqqdpqvfaaieqerkrqhakieliasenfvsravmeaqgsvltnkyaqgypgrry
yggceyvdiveelarerakqlfgaehanvqphsgaqanmavyftvlehgdtvlgmnlshg
ghlthgspvnfsgvqynfvaygvdpethvidyddvrekarlhrpklivaaasaypriidf
akfreiadevgaylmvdmahiaglvaaglhpnpvpyahfvtttthktlrgprggmilcqe
qfakqidkaifpgiqggplmhviaakavafgealqddfkayakrvvdnakrlasalqneg
ftlvsggtdnhlllvdlrpqqltgktaekvldevgitvnkntipydpespfvtsgirigt
aavttrgfgleemdeiaaiiglvlknvgseqaleearqrvaaltdgg

    Sequence, based on observed residues (ATOM records): (download) 
    >2vguA (A:)
mkylpqqdpqvfaaieqerkrqhakieliasenfvsravmeaqgsvltnkyaqgypgrry
yggceyvdiveelarerakqlfgaehanvqphsgaqanmavyftvlehgdtvlgmnlshg
ghlthgspvnfsgvqynfvaygvdpethvidyddvrekarlhrpklivaaasaypriidf
akfreiadevgaylmvdmahiaglvaaglhpnpvpyahfvtttthktlrgprggmilcqe
qfakqidkaifpgiqggplmhviaakavafgealqddfkayakrvvdnakrlasalqneg
ftlvsggtdnhlllvdlrpqqltgktaekvldevgitvnkntipydpespfvtsgirigt
aavttrgfgleemdeiaaiiglvlknvgseqaleearqrvaaltdg