Lineage for Protein: Tumor necrosis factor (TNF)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2372079Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2372080Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2372081Family b.22.1.1: TNF-like [49843] (15 protein domains)
  6. 2372278Protein Tumor necrosis factor (TNF) [49848] (2 species)

Species:

  1. 2372279Human (Homo sapiens) [TaxId:9606] [49849] (20 PDB entries)
    1. Domains for 1a8m:
      1. 2372311Domain d1a8ma_: 1a8m A: [23868]
        mutant
      2. 2372312Domain d1a8mb_: 1a8m B: [23869]
        mutant
      3. 2372313Domain d1a8mc_: 1a8m C: [23870]
        mutant
    2. Domains for 1tnf:
      1. 2372326Domain d1tnfa_: 1tnf A: [23871]
      2. 2372327Domain d1tnfb_: 1tnf B: [23872]
      3. 2372328Domain d1tnfc_: 1tnf C: [23873]
    3. Domain for 1tnr:
    4. Domains for 2az5:
      1. 2372282Domain d2az5a_: 2az5 A: [127599]
        automated match to d1tnfa_
        complexed with 307
      2. 2372283Domain d2az5b_: 2az5 B: [127600]
        automated match to d1tnfa_
        complexed with 307
      3. 2372284Domain d2az5c_: 2az5 C: [127601]
        automated match to d1tnfa_
        complexed with 307
      4. 2372285Domain d2az5d_: 2az5 D: [127602]
        automated match to d1tnfa_
        complexed with 307
    5. Domains for 2tun:
      1. 2372332Domain d2tuna_: 2tun A: [23874]
        mutant
      2. 2372333Domain d2tunb_: 2tun B: [23875]
        mutant
      3. 2372334Domain d2tunc_: 2tun C: [23876]
        mutant
      4. 2372335Domain d2tund_: 2tun D: [23877]
        mutant
      5. 2372336Domain d2tune_: 2tun E: [23878]
        mutant
      6. 2372337Domain d2tunf_: 2tun F: [23879]
        mutant
    6. Domains for 2zjc:
      1. 2372290Domain d2zjca_: 2zjc A: [171243]
        automated match to d1a8ma_
        complexed with gol; mutant
      2. 2372291Domain d2zjcb_: 2zjc B: [171244]
        automated match to d1a8ma_
        complexed with gol; mutant
      3. 2372292Domain d2zjcc_: 2zjc C: [171245]
        automated match to d1a8ma_
        complexed with gol; mutant
    7. Domains for 2zpx:
      1. 2372329Domain d2zpxa_: 2zpx A: [171412]
        automated match to d1a8ma_
        mutant
      2. 2372330Domain d2zpxb_: 2zpx B: [171413]
        automated match to d1a8ma_
        mutant
      3. 2372331Domain d2zpxc_: 2zpx C: [171414]
        automated match to d1a8ma_
        mutant
    8. Domains for 3alq:
      1. 2372320Domain d3alqa_: 3alq A: [245160]
        automated match to d1a8ma_
        complexed with co
      2. 2372321Domain d3alqb_: 3alq B: [245161]
        automated match to d1a8ma_
        complexed with co
      3. 2372322Domain d3alqc_: 3alq C: [245162]
        automated match to d1a8ma_
        complexed with co
      4. 2372323Domain d3alqd_: 3alq D: [245163]
        automated match to d1a8ma_
        complexed with co
      5. 2372324Domain d3alqe_: 3alq E: [245164]
        automated match to d1a8ma_
        complexed with co
      6. 2372325Domain d3alqf_: 3alq F: [245165]
        automated match to d1a8ma_
        complexed with co
    9. Domain for 3l9j:
    10. Domain for 3wd5:
    11. Domain for 4g3y:
    12. Domain for 4tsv:
    13. Domains for 4tsw:
      1. 2372299Domain d4tswa_: 4tsw A: [309664]
        automated match to d5tswa_
        mutant
      2. 2372300Domain d4tswb_: 4tsw B: [309665]
        automated match to d5tswa_
        mutant
      3. 2372301Domain d4tswc_: 4tsw C: [309666]
        automated match to d5tswa_
        mutant
      4. 2372302Domain d4tswd_: 4tsw D: [309667]
        automated match to d5tswa_
        mutant
      5. 2372303Domain d4tswe_: 4tsw E: [309668]
        automated match to d5tswa_
        mutant
      6. 2372304Domain d4tswf_: 4tsw F: [309669]
        automated match to d5tswa_
        mutant
    14. Domains for 5m2i:
      1. 2372305Domain d5m2ia_: 5m2i A: [338539]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      2. 2372306Domain d5m2ib_: 5m2i B: [338554]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      3. 2372307Domain d5m2ic_: 5m2i C: [338538]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      4. 2372308Domain d5m2id_: 5m2i D: [338540]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      5. 2372309Domain d5m2ie_: 5m2i E: [338542]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
      6. 2372310Domain d5m2if_: 5m2i F: [338541]
        Other proteins in same PDB: d5m2ig_, d5m2ih_, d5m2ii_, d5m2ij_, d5m2ik_, d5m2il_
        automated match to d1a8ma_
    15. Domain for 5m2j:
    16. Domains for 5m2m:
      1. 2372314Domain d5m2ma_: 5m2m A: [338556]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
      2. 2372315Domain d5m2mb_: 5m2m B: [338555]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
      3. 2372316Domain d5m2mc_: 5m2m C: [338525]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
      4. 2372317Domain d5m2mg_: 5m2m G: [338616]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
      5. 2372318Domain d5m2mi_: 5m2m I: [338533]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
      6. 2372319Domain d5m2mm_: 5m2m M: [338552]
        Other proteins in same PDB: d5m2md1, d5m2md2, d5m2me1, d5m2me2, d5m2mf1, d5m2mf2, d5m2mh1, d5m2mh2, d5m2mj1, d5m2mj2, d5m2mn1, d5m2mn2
        automated match to d1a8ma_
    17. Domains for 5mu8:
      1. 2372338Domain d5mu8a_: 5mu8 A: [332502]
        automated match to d1a8ma_
        complexed with jni
      2. 2372339Domain d5mu8b_: 5mu8 B: [332482]
        automated match to d1a8ma_
        complexed with jni
      3. 2372340Domain d5mu8c_: 5mu8 C: [332470]
        automated match to d1a8ma_
        complexed with jni
      4. 2372341Domain d5mu8d_: 5mu8 D: [332413]
        automated match to d1a8ma_
        complexed with jni
      5. 2372342Domain d5mu8e_: 5mu8 e: [332515]
        automated match to d1a8ma_
        complexed with jni
      6. 2372343Domain d5mu8f_: 5mu8 F: [332415]
        automated match to d1a8ma_
        complexed with jni
      7. 2372344Domain d5mu8g_: 5mu8 G: [332520]
        automated match to d1a8ma_
        complexed with jni
      8. 2372345Domain d5mu8h_: 5mu8 H: [332513]
        automated match to d1a8ma_
        complexed with jni
      9. 2372346Domain d5mu8i_: 5mu8 I: [332417]
        automated match to d1a8ma_
        complexed with jni
      10. 2372347Domain d5mu8j_: 5mu8 J: [332469]
        automated match to d1a8ma_
        complexed with jni
      11. 2372348Domain d5mu8k_: 5mu8 K: [332516]
        automated match to d1a8ma_
        complexed with jni
      12. 2372349Domain d5mu8l_: 5mu8 L: [332481]
        automated match to d1a8ma_
        complexed with jni
      13. 2372350Domain d5mu8m_: 5mu8 M: [332512]
        automated match to d1a8ma_
        complexed with jni
      14. 2372351Domain d5mu8n_: 5mu8 N: [332479]
        automated match to d1a8ma_
        complexed with jni
      15. 2372352Domain d5mu8o_: 5mu8 O: [332426]
        automated match to d1a8ma_
        complexed with jni
      16. 2372353Domain d5mu8p_: 5mu8 P: [332514]
        automated match to d1a8ma_
        complexed with jni
      17. 2372354Domain d5mu8q_: 5mu8 Q: [332486]
        automated match to d1a8ma_
        complexed with jni
      18. 2372355Domain d5mu8r_: 5mu8 R: [332425]
        automated match to d1a8ma_
        complexed with jni
      19. 2372356Domain d5mu8s_: 5mu8 S: [332414]
        automated match to d1a8ma_
        complexed with jni
      20. 2372357Domain d5mu8t_: 5mu8 T: [332519]
        automated match to d1a8ma_
        complexed with jni
      21. 2372358Domain d5mu8u_: 5mu8 U: [332476]
        automated match to d1a8ma_
        complexed with jni
      22. 2372359Domain d5mu8v_: 5mu8 V: [332418]
        automated match to d1a8ma_
        complexed with jni
      23. 2372360Domain d5mu8w_: 5mu8 W: [332451]
        automated match to d1a8ma_
        complexed with jni
      24. 2372361Domain d5mu8x_: 5mu8 X: [332521]
        automated match to d1a8ma_
        complexed with jni
      25. 2372362Domain d5mu8y_: 5mu8 Y: [332466]
        automated match to d1a8ma_
        complexed with jni
      26. 2372363Domain d5mu8z_: 5mu8 Z: [332420]
        automated match to d1a8ma_
        complexed with jni
    18. Domains for 5tsw:
      1. 2372293Domain d5tswa_: 5tsw A: [23861]
        mutant
      2. 2372294Domain d5tswb_: 5tsw B: [23862]
        mutant
      3. 2372295Domain d5tswc_: 5tsw C: [23863]
        mutant
      4. 2372296Domain d5tswd_: 5tsw D: [23864]
        mutant
      5. 2372297Domain d5tswe_: 5tsw E: [23865]
        mutant
      6. 2372298Domain d5tswf_: 5tsw F: [23866]
        mutant
    19. Domain for 5uui:
    20. Domains for 5yoy:
      1. 3051892Domain d5yoyk1: 5yoy K:6-157 [351954]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
      2. 3051894Domain d5yoyl1: 5yoy L:6-157 [351956]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
      3. 3051896Domain d5yoyj1: 5yoy J:6-157 [351958]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
      4. 3051901Domain d5yoya1: 5yoy A:6-157 [351963]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
      5. 3051939Domain d5yoyc1: 5yoy C:6-157 [352001]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
      6. 3051956Domain d5yoyb1: 5yoy B:6-157 [352018]
        Other proteins in same PDB: d5yoya2, d5yoyb2, d5yoyc2, d5yoyd_, d5yoye_, d5yoyf_, d5yoyg_, d5yoyh_, d5yoyi_, d5yoyj2, d5yoyk2, d5yoyl2, d5yoym_, d5yoyn_, d5yoyo_, d5yoyp_, d5yoyq_, d5yoyr_
        automated match to d1a8ma_
  2. 2372365Mouse (Mus musculus) [TaxId:10090] [49850] (1 PDB entry)

More info for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like

Timeline for Protein Tumor necrosis factor (TNF) from b.22.1.1: TNF-like: