PDB entry 6ooy

View 6ooy on RCSB PDB site
Description: Asymmetric hTNF-alpha
Class: cytokine
Keywords: Tumour necrosis factor alpha, TNF, asymmetric, protein-protein interaction inhibitor, rheumatoid arthritis, CYTOKINE
Deposited on 2019-04-23, released 2019-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ooya_
  • Chain 'B':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ooyb_
  • Chain 'C':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6ooyc_
  • Heterogens: A7M, MRD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6ooyA (A:)
vrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6ooyA (A:)
tpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkg
qgcpshvllthtisriavsyqtkvnllsaikspckpwyepiylggvfqlekgdrlsaein
rpdyldfaesgqvyfgiial

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6ooyB (B:)
vrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6ooyB (B:)
psdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkgq
gcpshvllthtisriavsyqtkvnllsaikspcakpwyepiylggvfqlekgdrlsaein
rpdyldfaesgqvyfgiial

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6ooyC (C:)
vrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliys
qvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiyl
ggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6ooyC (C:)
kpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkgqgch
vllthtisriavsyqtkvnllsaikspckpwyepiylggvfqlekgdrlsaeinrpdyld
faesgqvyfgiial