Lineage for d4g3yc_ (4g3y C:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2777171Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2777172Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2777173Family b.22.1.1: TNF-like [49843] (15 proteins)
  6. 2777391Protein Tumor necrosis factor (TNF) [49848] (3 species)
  7. 2777392Species Human (Homo sapiens) [TaxId:9606] [49849] (33 PDB entries)
  8. 2777405Domain d4g3yc_: 4g3y C: [196713]
    Other proteins in same PDB: d4g3yh_, d4g3yl1, d4g3yl2
    automated match to d1a8ma_

Details for d4g3yc_

PDB Entry: 4g3y (more details), 2.6 Å

PDB Description: Crystal structure of TNF-alpha in complex with Infliximab Fab fragment
PDB Compounds: (C:) Tumor necrosis factor

SCOPe Domain Sequences for d4g3yc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4g3yc_ b.22.1.1 (C:) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}
dkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkgqgc
psthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfqlekg
drlsaeinrpdyldfaesgqvyfgiial

SCOPe Domain Coordinates for d4g3yc_:

Click to download the PDB-style file with coordinates for d4g3yc_.
(The format of our PDB-style files is described here.)

Timeline for d4g3yc_: