PDB entry 2tnf
View 2tnf on RCSB PDB site
Description: 1.4 a resolution structure of mouse tumor necrosis factor, towards modulation of its selectivity and trimerisation
Class: cytokine
Keywords: lymphokine, cytokine, cytotoxin, transmembrane, glycoprotein, signal-anchor
Deposited on
1998-10-12, released
1999-10-12
The last revision prior to the SCOPe 2.08 freeze date was dated
2017-10-11, with a file datestamp of
2017-10-06.
Experiment type: XRAY
Resolution: 1.4 Å
R-factor: N/A
AEROSPACI score: 0.52
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: protein (tumor necrosis factor alpha)
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2tnfa_ - Chain 'B':
Compound: protein (tumor necrosis factor alpha)
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2tnfb_ - Chain 'C':
Compound: protein (tumor necrosis factor alpha)
Species: Mus musculus [TaxId:10090]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d2tnfc_ - Heterogens: TRS, IPA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>2tnfA (A:)
lrsssqnssdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvys
qvlfkgqgcpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylg
gvfqlekgdqlsaevnlpkyldfaesgqvyfgvial
Sequence, based on observed residues (ATOM records): (download)
>2tnfA (A:)
sdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvysqvlfkgqg
cpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylggvfqlekg
dqlsaevnlpkyldfaesgqvyfgvial
- Chain 'B':
Sequence, based on SEQRES records: (download)
>2tnfB (B:)
lrsssqnssdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvys
qvlfkgqgcpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylg
gvfqlekgdqlsaevnlpkyldfaesgqvyfgvial
Sequence, based on observed residues (ATOM records): (download)
>2tnfB (B:)
sdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvysqvlfkgqg
cpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylggvfqlekg
dqlsaevnlpkyldfaesgqvyfgvial
- Chain 'C':
Sequence, based on SEQRES records: (download)
>2tnfC (C:)
lrsssqnssdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvys
qvlfkgqgcpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylg
gvfqlekgdqlsaevnlpkyldfaesgqvyfgvial
Sequence, based on observed residues (ATOM records): (download)
>2tnfC (C:)
sdkpvahvvanhqveeqlewlsqranallangmdlkdnqlvvpadglylvysqvlfkgqg
cpdyvllthtvsrfaisyqekvnllsavkspcpkdtpegaelkpwyepiylggvfqlekg
dqlsaevnlpkyldfaesgqvyfgvial