Lineage for d6x85b_ (6x85 B:)

  1. Root: SCOPe 2.08
  2. 2739516Class b: All beta proteins [48724] (180 folds)
  3. 2777171Fold b.22: TNF-like [49841] (1 superfamily)
    sandwich, 10 strands in 2 sheets; jelly-roll
  4. 2777172Superfamily b.22.1: TNF-like [49842] (2 families) (S)
  5. 2777173Family b.22.1.1: TNF-like [49843] (15 proteins)
  6. 2777391Protein Tumor necrosis factor (TNF) [49848] (3 species)
  7. 2777392Species Human (Homo sapiens) [TaxId:9606] [49849] (33 PDB entries)
  8. 2777455Domain d6x85b_: 6x85 B: [401032]
    automated match to d1a8ma_
    complexed with utv

Details for d6x85b_

PDB Entry: 6x85 (more details), 2.85 Å

PDB Description: crystal structure of tnfalpha with indolinone compound 9
PDB Compounds: (B:) Tumor necrosis factor

SCOPe Domain Sequences for d6x85b_:

Sequence, based on SEQRES records: (download)

>d6x85b_ b.22.1.1 (B:) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}
kpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkgqgcp
sthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiylggvfqlekgd
rlsaeinrpdyldfaesgqvyfgiial

Sequence, based on observed residues (ATOM records): (download)

>d6x85b_ b.22.1.1 (B:) Tumor necrosis factor (TNF) {Human (Homo sapiens) [TaxId: 9606]}
kpvahvvanpqaegqlqwlnrgvelrdnqlvvpseglyliysqvlfkgqgcpsthvllth
tisriavsyqtkvnllsaikspcqkpwyepiylggvfqlekgdrlsaeinrpdyldfaes
gqvyfgiial

SCOPe Domain Coordinates for d6x85b_:

Click to download the PDB-style file with coordinates for d6x85b_.
(The format of our PDB-style files is described here.)

Timeline for d6x85b_: