PDB entry 6op0

View 6op0 on RCSB PDB site
Description: Asymmetric hTNF-alpha
Class: cytokine
Keywords: Tumour necrosis factor alpha, TNF, asymmetric, protein-protein interaction inhibitor, rheumatoid arthritis, CYTOKINE
Deposited on 2019-04-23, released 2019-12-25
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-01-01, with a file datestamp of 2019-12-27.
Experiment type: XRAY
Resolution: 2.55 Å
R-factor: N/A
AEROSPACI score: 0.2 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6op0a_
  • Chain 'B':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6op0b_
  • Chain 'C':
    Compound: Tumor necrosis factor
    Species: Homo sapiens [TaxId:9606]
    Gene: TNF, TNFA, TNFSF2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d6op0c_
  • Heterogens: A7A, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >6op0A (A:)
svrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliy
sqvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiy
lggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6op0A (A:)
tpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkg
qgcpsthvllthtisriavsyqtkvnllsaikspcqretpakpwyepiylggvfqlekgd
rlsaeinrpdyldfaesgqvyfgiial

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >6op0B (B:)
svrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliy
sqvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiy
lggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6op0B (B:)
tpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliysqvlfkg
qgcphvllthtisriavsyqtkvnllsaikspceakpwyepiylggvfqlekgdrlsaei
nrpdyldfaesgqvyfgiial

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >6op0C (C:)
svrsssrtpsdkpvahvvanpqaegqlqwlnrranallangvelrdnqlvvpseglyliy
sqvlfkgqgcpsthvllthtisriavsyqtkvnllsaikspcqretpegaeakpwyepiy
lggvfqlekgdrlsaeinrpdyldfaesgqvyfgiial

    Sequence, based on observed residues (ATOM records): (download) 
    >6op0C (C:)
kpvahvvanegqlqwlngvelrdnqlvvpseglyliysqvlfkgqgcpsthvllthtisr
iavqtkvnllsaikspckpwyepiylggvfqlekgdrlsaeinrpdyldgqvyfgiial